Protein Alignment gogo and thsd1

DIOPT Version :10

• Sequence 1: NP_649200.2
• Gene: gogo / 40225
• FlyBaseID: FBgn0052227
• Length: 1272
• Species: Drosophila melanogaster
• Sequence 2: XP_002936776.3
• Gene: thsd1 / 100497491
• XenbaseID: XB-GENE-6044670
• Length: 848
• Species: Xenopus tropicalis
• Alignment Length: 878
• Identity: 179/878 - (20%)
• Similarity: 283/878 - (32%)
• Gaps: 233/878 - (26%)

  Fly   177 CQTFLIGGRYEMQVVSNLKSVN----RSEVTTTLVPAQDERLHQTLDVRWPSAEMIVSPVRLKTY 237
            |..|:..|.|:.|:|...|:.:    ||.:.....|.....|::|.::|.....:..:.....|:
 Frog    91 CFHFIAAGLYQFQIVFTEKNQSNIDWRSSILNVTWPRFHIDLNRTSNIRSFQIGVFSNEQFCLTF 155

  Fly   238 P-KHP-----VEVTLRFPEVNCNQSGSLAL----------PEFWLELIYCGKDRS---CNRNITP 283
            | |||     ||.|..|.|:....|....|          |..|:| ..|...|.   ...::.|
 Frog   156 PDKHPRVLLEVEHTHSFQELEGLSSDRFMLYKTYKEIPLSPSQWVE-FECASVRPETFITVSLKP 219

  Fly   284 TSVLFAEQIRGFPKNKSLHLGCELFGLAGNYAVQLRPMIPAQNVPTTRRLLSVDWSDEFVFNVYA 348
            |   |:|.:..|                         |.|...|.|.|..|        |.:...
 Frog   220 T---FSESLIAF-------------------------MGPVDLVKTFRYKL--------VTSAEQ 248

  Fly   349 RSIFPCDPHTGIGVLYEYPGCILEQGDRVRLYAR-LRADVASLKPPTSLHYVSEQRVVKSQHSLY 412
            |    ||....:.|:  .|.|....| :|.:|.. ||   .|.:..|:|   :|..:........
 Frog   249 R----CDASVNVNVI--PPPCNYADG-KVIVYKEVLR---GSAETSTTL---AENVLQTGDKVAQ 300

  Fly   413 FACEHFSEKYVEYCFVYVSQAISGAVADV--RMDCVPTLPVSDSDTGGWGPWSEWTPCSTNCLGG 475
            |.|..|.....:|||.:.  ..||.:...  ..:||......:|    ||.|..|:|||..|..|
 Frog   301 FNCTLFDIGRNKYCFEFF--IASGKIYSFLGAKECVGIRREIES----WGLWQSWSPCSVTCGDG 359

  Fly   476 TRNRYRFC---DSPPPRYGAKFCEGPSVETQKCGKSIADTWDCIYETSGTVITKENSTEVSQEIG 537
            .|.|:|.|   .|..|.     |.|.:.||..|......:......:..|..:|:..|..:..|.
 Frog   360 ERERFRECLTTSSEKPA-----CRGRAKETSLCSLEECTSISVKPSSKSTTHSKDTKTSNTVTIA 419

  Fly   538 PGCRCGCIV------------HLGSSKPKRIIAGATQSCPGR-------------SF----WLIQ 573
            ....|..|:            |........:...:|.|..||             ||    ..:.
 Frog   420 GISLCLTIIIITIVITVWRKFHKTQKCSSTVKHNSTHSGNGRKNSDEENIYQMRESFSDMGEGLH 484

  Fly   574 VDGEESISLALSFLRLPCATQYIKVRDGPSLSSTLLVELNGGGLILKGAGVPVVVDSTGGQLLVE 638
            .:.|:::.:.|::      .|.::|.:..|......::.|...||     .|:.......|.|.|
 Frog   485 ENVEDTVDIPLTY------RQSMRVAEEKSGQENDNLQSNVQKLI-----PPIFSYRLAQQQLKE 538

  Fly   639 ------------FSAGDGPAGNATQE---ASPACTGGFMANVQQR-------LATRSSNSSITLV 681
                        :.....|..:...:   |.|:.|.....|:..:       :..|:.:......
 Frog   539 MKQRGLTEATKLYHVSQNPMSDTVVDGALAPPSVTDNCDDNIANKFRLQSPFIEQRNLHPQCHGE 603

  Fly   682 AATRLSGKTRSVVHKSMSRLRFTLVHLSAMIFASIIIIISSLLGAQYVVRY--RKYHLAVARRQD 744
            .:|.||      .::|.|..: ||.||            |..:.....|||  |.||..:..|:.
 Frog   604 RSTPLS------PYQSTSPCQ-TLPHL------------SQFMNQDPKVRYIERPYHKNINFRRT 649

  Fly   745 EGSRLHTPR-------ASLSSLQGPPSRAMSTTTLLSEVIYMVKMRPKHHLRHSILRESVDAENL 802
              |..|..:       .|||:|.  |.:.|:.........|....|.||.    .:|.....|:.
 Frog   650 --SSFHETKHNKPFRERSLSTLS--PRQTMAYNPRTRTWQYATTDRSKHR----SIRAEKSPEHF 706

  Fly   803 TKETEFKESDSQGMLAKCAEIKELGSSASMVTLRNERSSPARSLDTGSIIGSPSSAEAELAAVHS 867
            .|...| .:|.....:|...:....|...:::.|:                    |.|:.:.:..
 Frog   707 AKSANF-TADPVDFSSKNLYMWSSESKHDLISSRH--------------------AAAKASKLER 750

  Fly   868 RSESKDSPSDEPIE---------PPSCKDS-ARDSESIISSGMSSLCNSPPMNSKRLSKYSDRYD 922
            ..:::......||:         .|:.||| .|:|....:......|.|.|.    .:.|| .||
 Frog   751 LEQNRVKKGSSPIDKSWNRVQDYSPTFKDSYERNSPFSPAQNRREKCQSFPW----AADYS-FYD 810

  Fly   923 AVTLKL---------LSSRLDESLQDASSLLSV 946
            ..:.:|         |......:.:|.:|.||:
 Frog   811 NSSFRLTEAEQQMIDLPGYFASNEEDETSTLSM 843

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gogo	NP_649200.2	TSP1	459..505	CDD:214559	19/48 (40%)
		CUB	<570..640	CDD:412131	12/81 (15%)
thsd1	XP_002936776.3	TSP1	343..392	CDD:214559	20/53 (38%)