Protein Alignment Clc and cltb

DIOPT Version :10

• Sequence 1: NP_524178.2
• Gene: Clc / 40221
• FlyBaseID: FBgn0024814
• Length: 219
• Species: Drosophila melanogaster
• Sequence 2: XP_012814356.1
• Gene: cltb / 496489
• XenbaseID: XB-GENE-954481
• Length: 223
• Species: Xenopus tropicalis
• Alignment Length: 234
• Identity: 80/234 - (34%)
• Similarity: 123/234 - (52%)
• Gaps: 40/234 - (17%)

  Fly     5 DDF-------AAKEDVDPAAEFLAREQSALGDLEAEITGGSASAPPAASTDEGLGELLGGT-ASE 61
            |||       |.:.:.||||.|||:::|.:..:|               .|||.|.:.|.: ..|
 Frog     3 DDFGFFETGAAGETEEDPAAAFLAQQESEIAGIE---------------NDEGFGVVQGDSPEEE 52

  Fly    62 GDLLSAGGTGGLESSTGSFEVIGGESNEPVGISGPPPSREEPEKIRKWREEQKQRLEEKDIEEER 126
            .:::.....|.:..:...::.....|:....|:......:|||.:||||||||.||||.|...:.
 Frog    53 PEMVDFNDFGTIPMNGELYQETSDYSDGYAAIAQADRLTQEPESLRKWREEQKTRLEELDAASKV 117

  Fly   127 KKEELRQQSKKELDDWLRQIGESISKTKLASRNAEK-----------------QAATLENGTIEP 174
            .::|.|:::||:||:|.::..|.|.|.|:::|.|:|                 :|...:....|.
 Frog   118 TEQEWREKAKKDLDEWYQRQSEQIEKNKVSNRIADKAFYQQPNAEVIGYVASDEAMASDTKEEET 182

  Fly   175 GTEWERIAKLCDFNPKVNKAGKDVSRMRSIYLHLKQNPI 213
            ||||||:|:|||||||.:|..|||||:||:.:.|||.|:
 Frog   183 GTEWERVARLCDFNPKSSKQSKDVSRLRSVLISLKQTPL 221

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Clc	NP_524178.2	Clathrin_lg_ch	11..211	CDD:460056	74/217 (34%)
cltb	XP_012814356.1	Clathrin_lg_ch	3..219	CDD:460056	78/230 (34%)