Protein Alignment Su(Tpl) and ELL3

DIOPT Version :10

• Sequence 1: NP_649155.3
• Gene: Su(Tpl) / 40171
• FlyBaseID: FBgn0014037
• Length: 1059
• Species: Drosophila melanogaster
• Sequence 2: NP_079441.1
• Gene: ELL3 / 80237
• HGNCID: 23113
• Length: 397
• Species: Homo sapiens
• Alignment Length: 309
• Identity: 70/309 - (22%)
• Similarity: 132/309 - (42%)
• Gaps: 57/309 - (18%)

  Fly   646 SSSSGYETQQDRQRSTTPMSSNRSSASSSTTPPKLAASFV----PAATSGSAS--GTSKQRMPPQ 704
            ||..|:...:|.:...:..::...|...:.:.|::|...|    |.|::...|  |:|::.|...
Human   123 SSVQGHNLTEDARHPESWQNTGGYSEGDAVSQPQMALEEVSVSDPLASNQGQSLPGSSREHMAQW 187

  Fly   705 Q--SDYNSYNSNNAQHVASN-SKKRMGSVGPSGGSNGQRQRSASGSNSGYQQ--------VPPPS 758
            :  |..:..|....|.:.|: |:||:           .::||...:....::        ||.|
Human   188 EVRSQTHVPNREPVQALPSSASRKRL-----------DKKRSVPVATVELEEKRFRTLPLVPSP- 240

  Fly   759 SNSRSSIQQQNQHQKQQVQQKQAPSQQQQQQQQQYHQQAKHPSPSQQLAAAAHAYAHATADTDSS 823
               ...:..|:..:.:..:|:......:.:......:.::.|||..
Human   241 ---LQGLTNQDLQEGEDWEQEDEDMDPRLEHSSSVQEDSESPSPED------------------- 283

  Fly   824 ATPRYDFSQYVPIQTLEVRRRYKTEFESDYDEYRKLLTRVEDVRNRFQDLSERLESARRCDNGYG 888
             .|.| ..||..|.:.|.:..|:.:||:||.|||.|..||.....||.:|...::..||   |..
Human   284 -IPDY-LLQYRAIHSAEQQHAYEQDFETDYAEYRILHARVGTASQRFIELGAEIKRVRR---GTP 343

  Fly   889 DYDHIKRQIVCEYERINND-RTIGEDKERFDYLHAKLAHIKQLVMDYDK 936
            :|..::.:|:.||::.... .:..|:|.|.:|||.||:|||.|::::::
Human   344 EYKVLEDKIIQEYKKFRKQYPSYREEKRRCEYLHQKLSHIKGLILEFEE 392

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(Tpl)	NP_649155.3	ELL	16..462	CDD:463068
		Occludin_ELL	833..936	CDD:462140	36/103 (35%)
ELL3	NP_079441.1	ELL	17..>118	CDD:463068
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	164..219		14/65 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	237..284		8/70 (11%)
		Occludin_ELL	291..391	CDD:462140	36/102 (35%)