Protein Alignment Su(Tpl) and Ell2l1

DIOPT Version :10

• Sequence 1: NP_649155.3
• Gene: Su(Tpl) / 40171
• FlyBaseID: FBgn0014037
• Length: 1059
• Species: Drosophila melanogaster
• Sequence 2: XP_017457910.1
• Gene: Ell2l1 / 689396
• RGDID: 1593468
• Length: 634
• Species: Rattus norvegicus
• Alignment Length: 887
• Identity: 177/887 - (19%)
• Similarity: 292/887 - (32%)
• Gaps: 300/887 - (33%)

  Fly    98 DATGAGGGGGRKFGFTINNMEGTLECVQQQQRSLGVLGAVTLRMRIHANEDVYDSTRTKMAIAEE 162
            |...|.||.|..   .|.:.||.:...:......|::....|.|.|
  Rat     5 DYVAAFGGKGTG---KIMHPEGQMPVTEADNIDPGLVNVSRLPMGI------------------- 47

  Fly   163 TEKSKCIREIKP-NQSDIGRKVKKPPSAIQSSASTASAFSSNSSNSGLTTTAFHHHSNSNNSGNN 226
               |:.|.:..| .||:     |.|      |.|..|.|......:.:|.|    ||:::....|
  Rat    48 ---SRSIFQASPLYQSN-----KHP------SPSQVSQFQGFQQLNKITPT----HSSTDIKAFN 94

  Fly   227 NNRSSSSSNSFNSNNHSRKLGS---------SPFNGLGVGSSSSSSAFASRS-------PNPSTL 275
            ...||.|::|     ...|:|:         .|||.|   .|.......|||       |...|
  Rat    95 FQLSSMSNDS-----QQEKIGNPQPNISNSRPPFNCL---QSIQDKTTVSRSGMSVQMTPERMT- 150

  Fly   276 GAIGTVNGSGVVGGRYGGGAASSLASTFANGISQGY-----------HNLSGSSPRDSMTAGTSS 329
                              .|....::|:.| |.:.|           |.:...:|....|:..:.
  Rat   151 ------------------EAEEKSSNTWKN-IRKSYVQKKVSAQKVPHFVPDQAPERKKTSPLNP 196

  Fly   330 ATASSVISSRNKMPSGGLTSSNSNSSSSSRSANSKSSGGNKMSDVSRRNIRERLIHLLALKAFKK 394
            |.|    ..:::|.:|                            :..|:.|:|:|||||||.:||
  Rat   197 AYA----IRKSRMING----------------------------IHMRSFRDRVIHLLALKDYKK 229

  Fly   395 PELFARLKNEGIRDRERNQITNILMDISTMSHNT--YNLRRQMWNDVDENWPFFSEQEVQQLKRR 457
            .||..:|:.:||:..:.|.:..||:.::.::..|  |.|:..::.:|..:||.:::::.|.|...
  Rat   230 SELLVQLQKDGIKINDSNFLGKILLQVANLNATTLSYTLKDSIFKEVQRDWPGYNKEDKQSLDLV 294

  Fly   458 KPQNLTPPMSSDAGSSTSGQSPTSTHTGSPPPPSSNGGPGGVGSGAGGTSMKRTSL--EYDETMF 520
            ..:.|.|                 .|..:..                 |..|.||:  :.|:|..
  Rat   295 LSRKLHP-----------------FHNATEV-----------------THSKETSVISKTDDTSS 325

  Fly   521 STVQPKKQRISHYKK-DT---PPSGTSYSSAGVSMSLGSSGSSSRSRYTPPQRQPGPLDDHSTTD 581
            |     |....|... ||   ...|.....:.|.::.....||.:|...|
  Rat   326 S-----KDHFLHLSDIDTLIKNKGGLCSPKSAVQLASNGYVSSEKSMILP--------------- 370

  Fly   582 LSYNVLDNIVEFMSSTAAATQQ---SMEQQQHPRSNSSNNRRGSSSLAGTSNGGNNKDKRNSTGS 643
                          .:||.|:.   .:.....|.||        |.|...||.       |.:.:
  Rat   371 --------------CSAAPTKYVTLPLPNSHLPISN--------SPLLIKSNS-------NISCA 406

  Fly   644 NSSSSSGYETQQ-DRQRSTTPMSSNRSSASSSTTPPKLAASFVPAATSGSASGTSKQRMPPQQSD 707
            ...|.|.|.... ....||.....|:.::|.               ||..||...|..||
  Rat   407 PERSESQYTCDSIHHDGSTIEREMNKCTSSE---------------TSSCASVQKKHSMP----- 451

  Fly   708 YNSYNSNNAQHVASNSKKRMGSVGPSGGSNGQRQRSASGSNSGYQQVPPPSSNSRSSIQQQNQHQ 772
                  |..||......|         .:..:|:.:.....:..:::|....|.:..|.:.|.::
  Rat   452 ------NEMQHFMPEKFK---------CAFAKRKTTIPNYITSMKEIPKIDFNKQDEIMESNSNK 501

  Fly   773 KQQVQQKQAPSQQQQQQQQQYHQQAKHPSPSQQLAAAAHAYAHATADTDSSATPRYDFSQYVPIQ 837
            :                                   ...|:|.:.....:..||.| .|.|..|.
  Rat   502 E-----------------------------------VKKAFADSGKFVTTCGTPEY-LSNYSIIV 530

  Fly   838 TLEVRRRYKTEFESDYDEYRKLLTRVEDVRNRFQDL-SERLESARRCDNGYGDYDHIKRQIVCEY 901
            :.:.|:.|:.||.:||.||:.:..:::.......|| |||    :....|..:|..|.::|..||
  Rat   531 SSDQRQYYEDEFRADYSEYQAMYDKIQISCTPIIDLDSER----KGFSPGSKEYQDITKKISIEY 591

  Fly   902 ERINN-DRTIGEDKERFDYLHAKLAHIKQLVMDYDKTLMSAT 942
            :::.. :....|:|.:..:|:.||.|||:|:.|:|...:.:|
  Rat   592 QKMRQLNPKFCEEKNKCVFLYNKLIHIKKLINDFDNQKVKST 633

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(Tpl)	NP_649155.3	ELL	16..462	CDD:463068	84/393 (21%)
		Occludin_ELL	833..936	CDD:462140	31/104 (30%)
Ell2l1	XP_017457910.1	ELL	58..299	CDD:463068	69/315 (22%)
		Occludin_ELL	526..627	CDD:462140	31/104 (30%)