Protein Alignment Su(Tpl) and OCLN

DIOPT Version :10

• Sequence 1: NP_649155.3
• Gene: Su(Tpl) / 40171
• FlyBaseID: FBgn0014037
• Length: 1059
• Species: Drosophila melanogaster
• Sequence 2: NP_002529.1
• Gene: OCLN / 100506658
• HGNCID: 8104
• Length: 522
• Species: Homo sapiens
• Alignment Length: 264
• Identity: 56/264 - (21%)
• Similarity: 97/264 - (36%)
• Gaps: 66/264 - (25%)

  Fly   693 ASGTSKQRMPPQQSDYNSYNSNNAQHVASNSKKRMGSVGPSG-GSNGQRQRSASGSNSGYQQVPP 756
            ::||  |.:|...|||               .:|:.|  |.. .|||:.........|.|:..|.
Human   302 SAGT--QDVPSPPSDY---------------VERVDS--PMAYSSNGKVNDKRFYPESSYKSTPV 347

  Fly   757 PSSNSRSSIQQQNQHQKQQVQQKQAPSQQQQQQQQQYHQQAKHPSPSQQLAAAAHAYAHATADTD 821
            |                :.||:....|.....:|.:|.......:||::..|...|......:.|
Human   348 P----------------EVVQELPLTSPVDDFRQPRYSSGGNFETPSKRAPAKGRAGRSKRTEQD 396

  Fly   822 SSATPRYDFS---------------QYVPIQTLEVRRRYKTEFESDYDEYRKLLTRVEDVRNRFQ 871
            ...|   |::               :|.||.:.:.|:.||..|::...||:.|.:.::::.....
Human   397 HYET---DYTTGGESCDELEEDWIREYPPITSDQQRQLYKRNFDTGLQEYKSLQSELDEINKELS 458

  Fly   872 DLSERLESARRCDNGY----GDYDHIKRQIVCEYERINNDRTIGEDKERFDYLHAKLAHIKQLVM 932
            .|.:.|:..|.....|    .:|:.:|        ::.........|.....|.:||:|||::|.
Human   459 RLDKELDDYREESEEYMAAADEYNRLK--------QVKGSADYKSKKNHCKQLKSKLSHIKKMVG 515

  Fly   933 DYDK 936
            |||:
Human   516 DYDR 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(Tpl)	NP_649155.3	ELL	16..462	CDD:463068
		Occludin_ELL	833..936	CDD:462140	26/106 (25%)
OCLN	NP_002529.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20
		MARVEL	57..263	CDD:366555
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	360..407		9/49 (18%)
		Occludin_ELL	420..519	CDD:462140	26/106 (25%)