Protein Alignment Su(Tpl) and ell

DIOPT Version :10

• Sequence 1: NP_649155.3
• Gene: Su(Tpl) / 40171
• FlyBaseID: FBgn0014037
• Length: 1059
• Species: Drosophila melanogaster
• Sequence 2: XP_002940254.2
• Gene: ell / 100380194
• XenbaseID: XB-GENE-1013705
• Length: 626
• Species: Xenopus tropicalis
• Alignment Length: 958
• Identity: 201/958 - (20%)
• Similarity: 316/958 - (32%)
• Gaps: 410/958 - (42%)

  Fly    15 LSTGNYG--MSQSHRYTDDSKEYIIVKLTDSAFRAIEEYQRDDNAKRLQPGQRAKIQFVGNTGVI 77
            ||.|..|  :|..|           |||||||.||.|.||....:..|:|.    |:|.|:.|.|
 Frog    36 LSCGRVGGRVSVFH-----------VKLTDSALRAFESYQNSRASLNLKPA----IRFQGSQGQI 85

  Fly    78 QFPRP--ATDANGIPNANGNGSDATGAGGGGGRKFGFTINNM-----EGTLECVQQQQRS----- 130
            ..|:|  .|:.                     |.|.|.::|:     :|:.:|:||..:|
 Frog    86 TIPQPECPTEV---------------------RTFTFYLSNVGRDSPQGSFDCIQQYIQSNGNVK 129

  Fly   131 LGVLGAVTLRMRIHANEDVYDSTRTKMAIAEETEKSKCIREIKPNQSDIGRK---VKKP----PS 188
            |..||::..::.:.|.:|.|...|..||.|||..||:....||.. |..|.|   |:||    |.
 Frog   130 LDCLGSIQDKITVCATDDSYQKARQSMAQAEEENKSRGAIVIKMG-SRYGVKKVQVRKPAPGVPD 193

  Fly   189 AIQSSASTASAFSSNSSNSGLTTTAFHHHSNSNNSGNNNNRSSSSSNSFNSNNHSRKLGSSPFNG 253
            |:.|
 Frog   194 AVPS------------------------------------------------------------- 197

  Fly   254 LGVGSSSSSSAFASRSPNPSTLGAIGTVNGSGVVGGRYGGGAASSLASTFANGISQGYHNLSGSS 318
                         .:.|.|..|.
 Frog   198 -------------RKHPTPVNLA------------------------------------------ 207

  Fly   319 PRDSMTAGTSSATASSVISSRNKMPSGGLTSSNSNSSSSSRSANSKSSGGNKMSDVSRRNIRERL 383
                                                     ||..|:|.|     :|.|..::|:
 Frog   208 -----------------------------------------SAIKKTSTG-----LSLRPFKDRV 226

  Fly   384 IHLLALKAFKKPELFARLKNEGIRDRERNQITNILMDISTMSHN--TYNLRRQMWNDVDENWPFF 446
            :||||||.:|||||..||:.:|:..:|::.:..:|..::.:|..  ||.|:..::.:|.::||.:
 Frog   227 VHLLALKPYKKPELILRLQKDGLSVQEKDLLDGLLQQVANLSAKDCTYTLKDCLYKEVQKDWPGY 291

  Fly   447 SEQEVQQLKRRKPQNLTPPMSSDAGSSTSGQSPTSTHTGSPPPPSSNGGPGGVGSGAGGTSMKRT 511
            ||.:.|.|||...:.|           ...|:| ||..|...|
 Frog   292 SEGDQQLLKRILARKL-----------LQQQNP-STQPGDTAP---------------------- 322

  Fly   512 SLEYDETMFSTVQPKKQRISHYKKDTPPSGTSYSSAGVSMSLGSSGSSSRSRYTPPQRQPGPLDD 576
                       :.|.|:.::                              |....||::| |.:.
 Frog   323 -----------LSPPKENVN------------------------------SNSPLPQKRP-PQNS 345

  Fly   577 HSTTDLSYNVLDNIVEFMSSTAAATQQSMEQQQHPRSNSSNNRRGSSSLAGTSNGGNNKDKRNST 641
            ..|..||..:  .|..|               :|....:.|.:..||         |.||...:|
 Frog   346 DFTDPLSKKL--RISRF---------------KHHSQPTFNGKLSSS---------NGKDSLAAT 384

  Fly   642 GSNSSSSSGYETQQDRQRSTTPMSSNRSSASSSTTPPKLAASFVPAATSGSASGTSKQRMPPQQS 706
            .|...||.                            |.:::|.:||:                 .
 Frog   385 PSQIPSSD----------------------------PVISSSHLPAS-----------------H 404

  Fly   707 DYNSYNSNNAQH---VASNSKKRMGSVGPSGGSNGQRQRSASGSNSGYQQVPPPSSNSRSSIQQQ 768
            |..|.:|.:.||   |:..:.:|:|                        ..|...|::...:...
 Frog   405 DPLSDSSTDTQHRDCVSQEASERLG------------------------HPPQTDSHAEGKLNCN 445

  Fly   769 NQHQKQQVQQKQAPSQQQQQQQQQYHQQAKHPSPS---------QQLAAAAHAYAHATADTDSSA 824
            :||.|.:.:.|:...:::.:::.|..|.......|         |.......|.::::..|.:|.
 Frog   446 SQHAKPKKKSKKHKEKERSKEKLQEKQNCTPVKNSGVTGGTGTVQDTIDLNGACSNSSVPTSTSE 510

  Fly   825 TPRYDFSQYVPIQTLEVRRRYKTEFESDYDEYRKLLTRVEDVRNRFQDLSERLESARRCDNGYGD 889
            .|.| ..:|..|.:.|:|:.||.:|.::|.|||.|..|:|.:..||..|..:|:  :.| .|..:
 Frog   511 MPDY-LLKYAAISSQELRQSYKNDFNAEYSEYRDLHARIERITRRFTQLDSQLK--QLC-QGSEE 571

  Fly   890 YDHIKRQIVCEYERI-NNDRTIGEDKERFDYLHAKLAHIKQLVMDYDK 936
            |..|..||:.||.:| ..:....|:|.|.:|||.||||||:|:..||:
 Frog   572 YKTIHDQILQEYRKIKKTNPNYSEEKNRCEYLHNKLAHIKKLIAQYDQ 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(Tpl)	NP_649155.3	ELL	16..462	CDD:463068	101/468 (22%)
		Occludin_ELL	833..936	CDD:462140	41/103 (40%)
ell	XP_002940254.2	ELL	30..307	CDD:463068	102/469 (22%)
		Occludin_ELL	518..619	CDD:462140	41/103 (40%)