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Protein Alignment Mi-2 and BTAF1

DIOPT Version :10

Sequence 1:	NP_001014591.1	Gene:	Mi-2 / 40170	FlyBaseID:	FBgn0262519	Length:	1983	Species:	Drosophila melanogaster
Sequence 2:	NP_003963.1	Gene:	BTAF1 / 9044	HGNCID:	17307	Length:	1849	Species:	Homo sapiens

Alignment Length:	673	Identity:	190/673 - (28%)
Similarity:	296/673 - (43%)	Gaps:	145/673 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   698 PVKHYTPPPEKPTTDLKKKYEDQPAFLE---------------GTGMQLHPYQIEGINWLRYSWG 747
            |::...|.|...:.:|.:....:..|||               ....:|..||.:|:|||.:...
Human  1218 PLEAGIPDPPNMSAELIQLKAKERHFLEQLLDGKKLENYKIPVPINAELRKYQQDGVNWLAFLNK 1282

  Fly   748 QGIDTILADEMGLGKTIQTVTFL----------YSLYKEGHCRG-PFLVAVPLSTLVNWEREFEL 801
            ..:..||.|:||||||:|::..|          |:..|...|.. |.||..|.:...:|..|
Human  1283 YKLHGILCDDMGLGKTLQSICILAGDHCHRAQEYARSKLAECMPLPSLVVCPPTLTGHWVDE--- 1344

  Fly   802 WAPDFYCITYIGDKDSRAVIRENELSFEEGAIRGSKVSRLRTTQY--KFNVLLTSYELISMDAAC 864
                      :|...||..:  |.|.:     .|....|:|....  :.|:::.||:::..|...
Human  1345 ----------VGKFCSREYL--NPLHY-----TGPPTERIRLQHQVKRHNLIVASYDVVRNDIDF 1392

  Fly   865 LGSIDWAVLVVDEAHRLKSNQSKFFRILNSYTIAYKLLLTGTPLQNNLEELFHLLNFLSRDKFND 929
            ..:|.:...::||.|.:|:.::|..:.:...|..|:::|:|||:|||:.||:.|.:||.......
Human  1393 FRNIKFNYCILDEGHVIKNGKTKLSKAVKQLTANYRIILSGTPIQNNVLELWSLFDFLMPGFLGT 1457

  Fly   930 LQAFQGEF---------ADVSKEEQ------VKRLHEMLGPHMLRRLKTDVLKNMPSKSEFIVRV 979
            .:.|...:         |..|..||      :..||..:.|.:|||:|.|||:::|.|.......
Human  1458 ERQFAARYGKPILASRDARSSSREQEAGVLAMDALHRQVLPFLLRRMKEDVLQDLPPKIIQDYYC 1522

  Fly   980 ELSAMQKKFYK-----------------FILTKNYEALNSKSGGGSCSLINIMMDLKKCCNHPYL 1027
            .||.:|.:.|:                 ..|::..|....|:.|   .:...:..|:|.||||.|
Human  1523 TLSPLQVQLYEDFAKSRAKCDVDETVSSATLSEETEKPKLKATG---HVFQALQYLRKLCNHPAL 1584

  Fly  1028 --------FPSAAEEATTAAGGLYEINSLTKAAGKLVLLSKML---------------KQLKAQN 1069
                    |.:.||:.......|::|    :.|.||..|.::|               :.:.||
Human  1585 VLTPQHPEFKTTAEKLAVQNSSLHDI----QHAPKLSALKQLLLDCGLGNGSTSESGTESVVAQ- 1644

  Fly  1070 HRVLIFSQMTKMLDILE-DFLEGE--QYKYERIDGGITGTLRQEAIDRF-NAPGAQQFVFLLSTR 1130
            ||:|||.|:..||||:| |.|:..  ...|.|:||.|....|...:.|| |.|...  |.||:|.
Human  1645 HRILIFCQLKSMLDIVEHDLLKPHLPSVTYLRLDGSIPPGQRHSIVSRFNNDPSID--VLLLTTH 1707

  Fly  1131 AGGLGINLATADTVIIYDSDWNPHNDIQAFSRAHRIGQANKVMIYRFVTRNSVEERVTQVAKRKM 1195
            .||||:||..||||:..:.||||..|:||..|||||||...|.:||.:||.::||::..:.|.||
Human  1708 VGGLGLNLTGADTVVFVEHDWNPMRDLQAMDRAHRIGQKRVVNVYRLITRGTLEEKIMGLQKFKM 1772

  Fly  1196 MLTHLVVRPGMGGKGANFTKQELDDILRFGTE---DLFKEDDKEEAIHYDD--------KAVAEL 1249
            .:.:.|:            .||...:...||:   |||..|...:|...|.        |::.|.
Human  1773 NIANTVI------------SQENSSLQSMGTDQLLDLFTLDKDGKAEKADTSTSGKASMKSILEN 1825

  Fly  1250 LDRTNRGIEEKESWANEY-LSSF 1271
            |.    .:.::|.:.:|| |.:|
Human  1826 LS----DLWDQEQYDSEYSLENF 1844

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.