Protein Alignment Mi-2 and AT5G43530

DIOPT Version :10

• Sequence 1: NP_001014591.1
• Gene: Mi-2 / 40170
• FlyBaseID: FBgn0262519
• Length: 1983
• Species: Drosophila melanogaster
• Sequence 2: NP_199166.1
• Gene: AT5G43530 / 834373
• AraportID: AT5G43530
• Length: 1277
• Species: Arabidopsis thaliana
• Alignment Length: 1388
• Identity: 280/1388 - (20%)
• Similarity: 462/1388 - (33%)
• Gaps: 488/1388 - (35%)

  Fly    79 ESEEDSDFVQHDEEVEYPSTSKRGRKRKEEKQAAKEKESASSGMPSVEDVCSAFS--VCNVEIEY 141
            |..|...|.:.:.|:..|......|         ||.....|...||.::.|:.|  .|||::|.
plant    86 EIVESDSFREQNLEIGEPDLDVENR---------KEAMIIDSIENSVVEIVSSASGDDCNVKVEV 141

  Fly   142 SEEEL--QSLTTYKAFMHHVRPILQKENPKIAAPKL----VMLVAAKWREFCESNPHIQQEGGAA 200
            .|.||  ::|            ::.||..::....:    |.:|:.  ...|:.|..::..
plant   142 VEPELLVENL------------VVAKEEEEMIVDSIEDSVVEIVST--ASGCDCNVKVEVV---- 188

  Fly   201 GSGGSAGQARSVTGDEPEEPRSSRSSRNEK---PDDIYEEAVEEEEEEEEEEKKPRRKRSGRGKK 262
                           :||....:.....|:   .|.|.|..||......:.|
plant   189 ---------------DPELCVDNLVVVKEEEMIADSIAESVVETVSRGLDYE------------- 225

  Fly   263 GRRPSGKVPTLKIKLLGKRKRDSSDEEQDASGASERDSDLEFERMLQKSD-------DSADEKEA 320
                   ...:|:|           ||.|.....|.||  .|..:|:|.|       |...|...
plant   226 -------CVDVKVK-----------EEPDLGTKLEEDS--VFPNVLEKKDEVIKVLEDQPSEINK 270

  Fly   321 PVSSKADNSAPAAQDDGSGAPVVRKKAKTKIGNKFKKKNKLKKTKNFPEGEDGEHEHQDYCEVCQ 385
            .:..:.|:...:...||:.|                |:.|::.....|.|.:.
plant   271 KLEQENDDLFSSGDSDGTSA----------------KRRKMEMESYAPVGVES------------ 307

  Fly   386 QGGEIILCDTCPRAYHLVCLEPE-LDEPP----EGKWSCPHC------EADGGAAEEEDDDEHQE 439
                   |...|....:|  :|| ||.|.    |.:.|..|.      |....|.:.....|..:
plant   308 -------CILAPTPLRVV--KPEKLDTPEVIDLESEKSYTHVKMEPVEEIKVEAVKMSSQVEDVK 363

  Fly   440 FCRVCKDGGELLCCDSCPSAYHTFCLNPPLDT----IPDGDWRCPRCSCPPLTGKAEKIITWRWA 500
            |.|..|.               .:....|:..    :.|||:            ..||  .|...
plant   364 FSREQKS---------------VYVKKEPVGARKVKVEDGDF------------PVEK--DWYLV 399

  Fly   501 QRSNDDGPSTSKGSKNSNSRVREY----FIKWH-----NMSYWHCEWVPEVQLDVHH--PLMIRS 554
            .||.....|||||.|..::.:..:    ..||.     ..|...|..:..:.::..:  ..::||
plant   400 GRSLVTATSTSKGRKLEDNEIVNFTFSSVAKWKVPNIVRFSTKRCGEIGRLPMEWSNWAVSLLRS 464

  Fly   555 FQRKY---DMEEPPKFEESLDEA---------DTRYKRIQRHKDKVGMKANDDAEVLEERFYKNG 607
            .:.|.   .:..|| |...:.|.         .:.:..:.:...::|...|     ||...:.
plant   465 GKVKMLGRCVAAPP-FLTMMQEIMLYVSFYIHSSIFTDVSKSTWRIGSSPN-----LESTLHP-- 521

  Fly   608 VKPEWLIVQRVINHRTARDGSTMYLVKWRELPYDKS--TWEEEGDDIQGLRQAIDYYQDLRAVCT 670
                   :.::..|.|.:             ||.|:  |.||.....:.|....||  |.||...
plant   522 -------LLQLFKHLTIK-------------PYQKAEFTPEELNSRKRSLNLEDDY--DERAALL 564

  Fly   671 SETTQSRSKKSKKGRKSKLKVEDDEDRPVKHYTPPPEKPTTDLKKKYEDQPAFLEGTGMQLHPYQ 735
            :      ..|.:||.:..|:...||:...:.|.............:..:.|:.|.   ..|.|||
plant   565 A------IAKRRKGCQQSLEQNKDEEEAPESYMNRVVGAADSYNLEEMEAPSTLT---CNLRPYQ 620

  Fly   736 IEGINWLRYSWGQGIDT-----------------------------------------------I 753
            .:.:.|:..| .:|||.                                               |
plant   621 KQALYWMSES-EKGIDVEKAAETLHPCWEAYRICDERAPSIYLNIFSGEATIQFPTATQMARGGI 684

  Fly   754 LADEMGLGKTIQTVTFLYSL----------------------YKEGH-------CRGPFLVAVPL 789
            |||.||||||:.|:..:.:.                      .||.|       .:|..|:..|:
plant   685 LADAMGLGKTVMTIALILARPGRGNPENEDVLVADVNADKRNRKEIHMALTTVKAKGGTLIICPM 749

  Fly   790 STLVNWEREFELWA-PDFYCIT--YIGDK--DSRAVIRENELSFEEGAIRGSKVSRLRTTQYKFN 849
            :.|..|:.|.|..: ||...:.  |.||:  |::|:.                         ..:
plant   750 ALLSQWKDELETHSKPDTVSVLVYYGGDRTHDAKAIA-------------------------SHD 789

  Fly   850 VLLTSYELIS------MDAACLGSIDWAVLVVDEAHRLKSNQSKFFRILNSYTIAYKLLLTGTPL 908
            |:||:|.:::      |..:....|||..:|:||||.:||.:::..:.....:...:..||||||
plant   790 VVLTTYGVLTSAYKQDMANSIFHRIDWYRIVLDEAHTIKSWKTQAAKATFELSSHCRWCLTGTPL 854

  Fly   909 QNNLEELFHLLNFLSRDKFNDLQAFQGEFADVSKEEQ----------VKRLHEMLGPHMLRRLKT 963
            ||.||:|:.||.||..:.:.:       :|..||..|          :|.:..:|.|.||||.|.
plant   855 QNKLEDLYSLLCFLHVEPWCN-------WAWWSKLIQKPYENGDPRGLKLIKAILRPLMLRRTKE 912

  Fly   964 ------DVLKNMPSKSEFIVRVELSAMQKKFYKFILTKNYEALNSKSGGGS-----CSLINIMMD 1017
                  .::..:|.....::..|.|..::.||..:..::....:.....|.     .:::.:::.
plant   913 TRDKEGSLILELPPTDVQVIECEQSEAERDFYTALFKRSKVQFDQFVAQGKVLHNYANILELLLR 977

  Fly  1018 LKKCCNHPYLFPSAAEEATTAAGGLYEINSLT--------------------------------- 1049
            |::|||||:|..|.|:....|     :::||.
plant   978 LRQCCNHPFLVMSRADSQQYA-----DLDSLARRFLDNNPDSVSQNAPSRAYIEEVIQDLRDGNS 1037

  Fly  1050 ----------------------------------------------------------------- 1049
                                                                             
plant  1038 KECPICLESADDPVLTPCAHRMCRECLLTSWRSPSCGLCPICRTILKRTELISCPTDSIFRVDVV 1102

  Fly  1050 ---KAAGKLVLLSKMLKQLK--AQNHRVLIFSQMTKMLDILEDFLEGEQYKYERIDGGITGTLRQ 1109
               |.:.|:..|.|.|:::|  ....:.::|||.|..||:||..|....:::.|.||.:....|:
plant  1103 KNWKESSKVSELLKCLEKIKKSGSGEKSIVFSQWTSFLDLLEIPLRRRGFEFLRFDGKLAQKGRE 1167

  Fly  1110 EAIDRFNAPGAQQFVFLLSTRAGGLGINLATADTVIIYDSDWNPHNDIQAFSRAHRIGQANKVMI 1174
            :.:..||.. .|:.:.|:|.:|||:|:||..|.:|.:.|..|||..:.||..|.|||||...|.:
plant  1168 KVLKEFNET-KQKTILLMSLKAGGVGLNLTAASSVFLMDPWWNPAVEEQAIMRIHRIGQKRTVFV 1231

  Fly  1175 YRFVTRNSVEERVTQVAKRKMML 1197
            .||:.:::||||:.||..||..:
plant  1232 RRFIVKDTVEERMQQVQARKQRM 1254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mi-2	NP_001014591.1	CHDNT	138..191	CDD:462357	10/58 (17%)
		TNG2	<282..422	CDD:227367	30/151 (20%)
		PHD1_CHD_II	380..422	CDD:277006	10/46 (22%)
		PHD2_CHD_II	440..482	CDD:277007	7/45 (16%)
		CD1_tandem_CHD3-4_like	487..557	CDD:349314	17/80 (21%)
		CD2_tandem_CHD3-4_like	610..664	CDD:349309	11/55 (20%)
		PLN03142	720..>1234	CDD:215601	154/689 (22%)
		DUF1087	<1292..1334	CDD:461922
		CHDII_SANT-like	1380..1517	CDD:461920
		CHDCT2	1757..1902	CDD:462358
AT5G43530	NP_199166.1	HIRAN	402..490	CDD:214906	18/88 (20%)
		HepA	<542..1259	CDD:440319	169/763 (22%)
		RING-HC	1039..1079	CDD:438113	0/39 (0%)