Protein Alignment Mi-2 and CHR40

DIOPT Version :10

• Sequence 1: NP_001014591.1
• Gene: Mi-2 / 40170
• FlyBaseID: FBgn0262519
• Length: 1983
• Species: Drosophila melanogaster
• Sequence 2: NP_189077.1
• Gene: CHR40 / 822023
• AraportID: AT3G24340
• Length: 1132
• Species: Arabidopsis thaliana
• Alignment Length: 1191
• Identity: 262/1191 - (21%)
• Similarity: 430/1191 - (36%)
• Gaps: 366/1191 - (30%)

  Fly   208 QARSVTGDEPEEPRSSRSSRNEKPDDIYEEAVEEEEEEEEEEKKPRRKRSGRGK---------KG 263
            :::.::|:|.::.....:||.||......:|.         ...||:|:..|.|         :.
plant    25 KSKGISGEEEDQSLGCVNSRTEKRRVNMRDAC---------SPSPRKKKRRRRKDDDDDVVFVRT 80

  Fly   264 RRPSGKVPTLKIKLLGKRKRDSSDEEQDASGASERDSDLEF-ERMLQKSDDSADEKEAPVSSKAD 327
            ..|.|             |||  ||...::..:.:....:| :|:   .|..||::......||.
plant    81 EYPEG-------------KRD--DENVGSTSGNLQSKSFDFGDRV---CDFDADDRNLGCEEKAS 127

  Fly   328 NSAPAAQDD---------------------GSGAPVVRKKA------KTKIGNKFKKKNKLKKTK 365
            |..|...||                     || |.|:..:.      ..|:..   |:|.|.
plant   128 NFNPIDDDDDVVFVGTVQRENDHVEDDDNVGS-ASVISPRVCDFDEDDAKVSG---KENPLS--- 185

  Fly   366 NFPEGED---------GEHEH-QDY---CEVCQQGGEIILCDTCPRAYHLVCLEPEL-------- 409
              |:.:|         ||::| :|.   .|||    :|:|.|...|......:..|:
plant   186 --PDDDDDVVFLGTIAGENQHVEDVNAGSEVC----DILLDDANLRGEEKTYVSDEVVSLSSSSD 244

  Fly   410 -DEPP------EGKWSCPHCEADGGAA---EEEDDDEHQEFCRVCKDGGELLCCDSCPSAYHTFC 464
             :|.|      :.:......:.|.|.:   |:.:|.:..::.....|..::...||
plant   245 DEEDPLEELGTDSREEVSGEDRDSGESDMDEDANDSDSSDYVGESSDSSDVESSDS--------- 300

  Fly   465 LNPPLDTIPDGDWRCPRCSCPPLTGKAEKIITWRWAQRSNDDGPSTSKGSKNSNSRVREYFIKWH 529
                       |:.|                       |.|:...|...:.
plant   301 -----------DFVC-----------------------SEDEEGGTRDDAT-------------- 317

  Fly   530 NMSYWHCEWVPEVQLDVHHPLMIRSFQRKYD-----------MEEPPKFEE------SLDEADTR 577
                  ||..|..:  |:|....|:|:||::           :|....|:|      .:.|.|:|
plant   318 ------CEKNPSEK--VYHHKKSRTFRRKHNFDVINLLAKSMLESKDVFKEDIFSWDKIAEVDSR 374

  Fly   578 YKRIQRHKDKVGMKANDDAEVLEERFY-----KNGVKPEWLI-------VQRVINHRTARDGSTM 630
            ...:.|  :....|.|:..:..|.|.:     ||.:..|...       .:..||:.| .|...:
plant   375 EDPVVR--ESSSEKVNEHGKPRERRSFHRVREKNHLNGESFYGGEKLCDGEETINYST-EDSPPL 436

  Fly   631 YLVKWRELP--YDKSTWEEEGDDIQGLRQAIDYYQDLRAVCTSETTQSRSKKSKKGRKSKLK--- 690
            .|....|.|  .:|:..|:|.|.:         ::|:....|.|...| |...|.|.....|
plant   437 NLRFGCEEPVLIEKTEEEKELDSL---------WEDMNVALTLEGMHS-STPDKNGDMLCSKGTH 491

  Fly   691 --VEDDE-----------DRPVKHYTPPPEK--PTTDLKKKYEDQ----------------PAF- 723
              |.|||           ...:|..:|..:|  |:.:..||..|:                .:|
plant   492 DFVLDDEIGLKCVHCAYVAVEIKDISPAMDKYRPSVNDNKKCSDRKGDPLPNRLEFDASDPSSFV 556

  Fly   724 -----LEGTGMQ--------LHPYQIEGINWLRYSW------------------GQGIDTILADE 757
                 :|||..|        |:|:|.||..::   |                  |.| ..|::.:
plant   557 APLDNIEGTVWQYVPGIKDTLYPHQQEGFEFI---WKNLAGTTKINELNSVGVKGSG-GCIISHK 617

  Fly   758 MGLGKTIQTVTFLYSLYKEGHCRGPFLVAVPLSTLVNWEREFELWAPD--FYCITYI---GDKDS 817
            .|.|||..||.||.|..|......|.::| |.:.:..||.|...|..:  ||.:..:   |.:|:
plant   618 AGTGKTRLTVVFLQSYLKRFPNSHPMVIA-PATLMRTWEDEVRKWNVNIPFYNMNSLQLSGYEDA 681

  Fly   818 RAVIRENELSFEEGAIRGSKVSRLRTTQY--KFNVLLTSYELISMDAACLGSIDWAV-------- 872
            .||.|      .||....:.:..::...:  :.::|..||.|....||...:....|
plant   682 EAVSR------LEGNRHHNSIRMVKLVSWWKQKSILGISYPLYEKLAANKNTEGMQVFRRMLVEL 740

  Fly   873 ---LVVDEAHRLKSNQSKFFRILNSYTIAYKLLLTGTPLQNNLEELFHLLNFLSR--------DK 926
               ||:||.|..::..|..:::|.......::.|:||..|||.:||.::| .|:|        .:
plant   741 PGLLVLDEGHTPRNQSSLIWKVLTEVRTEKRIFLSGTLFQNNFKELSNVL-CLARPADKDTISSR 804

  Fly   927 FNDLQ--AFQGEFADVSKEEQVKRLHEMLGPHMLRRLKTDVLKNMPSKSEFIVRVELSAMQKKFY 989
            .::|.  :.:||...|::|.::..|..|:...:.....|.:.:::|...:.:|.:.....|||
plant   805 IHELSKCSQEGEHGRVNEENRIVDLKAMIAHFVHVHEGTILQESLPGLRDCVVVLNPPFQQKK-- 867

  Fly   990 KFILTKNYEALNSKSGGGSCSLINIMMDLKKCCNHPYLFPSAAEEATTAAGGL---------YEI 1045
              ||.:...:.|:.......|.:::...|..|||     |:..|:.......|         ||.
plant   868 --ILDRIDTSQNTFEFEHKLSAVSVHPSLYLCCN-----PTKKEDLVIGPATLGTLKRLRLKYEE 925

  Fly  1046 NSLTKAAGKLVLLSKMLKQLKAQNHRVLIFSQMTKMLDILE-------DFLEGEQY-----KYER 1098
            ...||.....:.:|..:|:      :||::||....|.::.       |:.||||.     |.|:
plant   926 GVKTKFLIDFIRISGTVKE------KVLVYSQYIDTLKLIMEQLIAECDWTEGEQILLMHGKVEQ 984

  Fly  1099 IDGGITGTLRQEAIDRFNAPGAQQFVFLLSTRAGGLGINLATADTVIIYDSDWNPHNDIQAFSRA 1163
            .|       ||..||.||.|.:...|.|.||:|...||:|..|..|:|.|..|||..:.||.|||
plant   985 RD-------RQHMIDNFNKPDSGSKVLLASTKACSEGISLVGASRVVILDVVWNPSVESQAISRA 1042

  Fly  1164 HRIGQANKVMIYRFVTRNSVE 1184
            .||||...|.||..:.:::.|
plant  1043 FRIGQKRAVFIYHLMVKDTSE 1063

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mi-2	NP_001014591.1	CHDNT	138..191	CDD:462357
		TNG2	<282..422	CDD:227367	40/195 (21%)
		PHD1_CHD_II	380..422	CDD:277006	10/59 (17%)
		PHD2_CHD_II	440..482	CDD:277007	5/41 (12%)
		CD1_tandem_CHD3-4_like	487..557	CDD:349314	10/69 (14%)
		CD2_tandem_CHD3-4_like	610..664	CDD:349309	12/62 (19%)
		PLN03142	720..>1234	CDD:215601	143/562 (25%)
		DUF1087	<1292..1334	CDD:461922
		CHDII_SANT-like	1380..1517	CDD:461920
		CHDCT2	1757..1902	CDD:462358
CHR40	NP_189077.1	HepA	<571..1082	CDD:440319	138/527 (26%)
		DEXHc_ATRX-like	577..830	CDD:350765	65/264 (25%)