Protein Alignment Mi-2 and RAD54

DIOPT Version :10

• Sequence 1: NP_001014591.1
• Gene: Mi-2 / 40170
• FlyBaseID: FBgn0262519
• Length: 1983
• Species: Drosophila melanogaster
• Sequence 2: NP_188552.3
• Gene: RAD54 / 821455
• AraportID: AT3G19210
• Length: 910
• Species: Arabidopsis thaliana
• Alignment Length: 1000
• Identity: 253/1000 - (25%)
• Similarity: 396/1000 - (39%)
• Gaps: 298/1000 - (29%)

  Fly   561 MEEPPKFEESL-----DEADTRYKRIQRHKDKVGMKANDDAEVL--------EERFYKNGVKPEW 612
            |||  :.||.|     |::...||  ...:|..|...|.:.|.|        .:|..|| ||...
plant     1 MEE--EDEEILSSSDCDDSSDSYK--DDSQDSEGENDNPECEDLAVVSLSSDADRKSKN-VKDLL 60

  Fly   613 ---LIVQRVINHRTARDGSTMYLVKWRELPYDKSTWEEEGDDIQGLRQAIDYYQDLRAVC----- 669
               |:|||                                   |.|...:....|..|||
plant    61 RGNLVVQR-----------------------------------QPLLPRVLSVSDGAAVCRKPFK 90

  Fly   670 --TSETTQSRSKKSKKGRKSKLKVEDDEDRPVKHYTPPPEKPTTDLKKKYEDQPAFL-------- 724
              .|....|..:.|::....|..|......||....|...:.:|::::..|::...|
plant    91 PPCSHGYDSTGQLSRRLSARKRFVPWGSSTPVVVALPTKLEASTNIERDEEEEVVCLPPDIEPLV 155

  Fly   725 ----EGTGMQ--------------LHPYQIEGINWLRYSWGQGI-------DTILADEMGLGKTI 764
                |..||.              |.|:|.||:.:: :....|:       ..||||:||||||:
plant   156 LWQSEEDGMSNVTTIMVHSVLVKFLRPHQREGVQFM-FDCVSGLHGSANINGCILADDMGLGKTL 219

  Fly   765 QTVTFLYSLYKEGHCRGPF----LVAVPLSTLVNWEREFELWAPDFYCITYIGDKDSRAVIRENE 825
            |::|.||:|..:|....|.    ::..|.|.:.|||.|.:.|         :||:.....:.|
plant   220 QSITLLYTLLCQGFDGTPMVKKAIIVTPTSLVSNWEAEIKKW---------VGDRIQLIALCE-- 273

  Fly   826 LSFEEGAIRG-SKVSRLRTTQYKFNVLLTSYELISMDAA--CLG-SIDWAVLVVDEAHRLKSNQS 886
             |..:..:.| ...:|.|:.   ..||:.|||...|.::  |.. |.|  :|:.|||||||::|:
plant   274 -STRDDVLSGIDSFTRPRSA---LQVLIISYETFRMHSSKFCQSESCD--LLICDEAHRLKNDQT 332

  Fly   887 KFFRILNSYTIAYKLLLTGTPLQNNLEELFHLLNFLSRDKFNDLQAFQ---------GEFADVSK 942
            ...|.|.|.|...::||:|||:||:|||.|.::||.:.....|...|:         |.....::
plant   333 LTNRALASLTCKRRVLLSGTPMQNDLEEFFAMVNFTNPGSLGDAAHFRHYYEAPIICGREPTATE 397

  Fly   943 EE------QVKRLHEMLGPHMLRRLKTDVLKNMPSKSEFIVRVELSAMQKKFYK-FILTKNYE-- 998
            ||      :...|...:...:|||....:..::|.|...:|..:::.:|...|. ||.:||.:
plant   398 EEKNLAADRSAELSSKVNQFILRRTNALLSNHLPPKIIEVVCCKMTTLQSTLYNHFISSKNLKRA 462

  Fly   999 -ALNSKSGGGSCSLINIMMDLKKCCNHPYL---------------------FP----SAAEEATT 1037
             |.|:|    ...::..:..|||.||||.|                     ||    |....|.|
plant   463 LADNAK----QTKVLAYITALKKLCNHPKLIYDTIKSGNPGTVGFENCLEFFPAEMFSGRSGAWT 523

  Fly  1038 AAGGLYEINSLTKAAGKLVLLSKMLKQLKAQ-NHRVLIFSQMTKMLDILEDFLEGEQYKYERIDG 1101
            ...|.:     .:.:||:.:||::|..|:.: :.|:::.|..|:.||:........:|.:.|:||
plant   524 GGDGAW-----VELSGKMHVLSRLLANLRRKTDDRIVLVSNYTQTLDLFAQLCRERRYPFLRLDG 583

  Fly  1102 GITGTLRQEAIDRFNAPGAQQFVFLLSTRAGGLGINLATADTVIIYDSDWNPHNDIQAFSRAHRI 1166
            ..|.:.||:.::|.|.|...:|.||||::|||.|:||..|:.::::|.||||.||.||.:|..|.
plant   584 STTISKRQKLVNRLNDPTKDEFAFLLSSKAGGCGLNLIGANRLVLFDPDWNPANDKQAAARVWRD 648

  Fly  1167 GQANKVMIYRFVTRNSVEERVTQVAKRKMMLTHLVVRPGMGGKGANFTKQELDDILRFG----TE 1227
            ||..:|.:|||::..::||:|.|....|..|..::            ..::.|:..|.|    ||
plant   649 GQKKRVYVYRFLSTGTIEEKVYQRQMSKEGLQKVI------------QHEQTDNSTRQGNLLSTE 701

  Fly  1228 DL-----FKEDDKEEAIHYDDKAVAELLDRTNRGIEEKESWANEYLSSFKVASYATKEEEEEEET 1287
            ||     |..|.:.|                   |.||.|              .::.:.:...|
plant   702 DLRDLFSFHGDVRSE-------------------IHEKMS--------------CSRCQNDASGT 733

  Fly  1288 EIIKQDAENS--DPAYWVKLLRHHYEQHQEDVGRSLGKGKRVRKQVNYTDGGV----------VA 1340
            |.|::..||:  |.|..:         .|||:|   |..|         |.|.          |.
plant   734 ENIEEGNENNVDDNACQI---------DQEDIG---GFAK---------DAGCFNLLKNSERQVG 777

  Fly  1341 ADTTRDDSNWQDNGSEYNS--------EYSAGSDE---------DG--------------GDDDF 1374
            .....|..:|   |..:.|        :.||| ||         ||              ..::.
plant   778 TPLEEDLGSW---GHHFTSKSVPDAILQASAG-DEVTFVFTNQVDGKLVPIESNVSPKTVESEEH 838

  Fly  1375 DDQNGAERKAKRRLERRDDRPLPPL 1399
            :......::|..:.::|...||.||
plant   839 NRNQPVNKRAFNKPQQRPREPLQPL 863

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mi-2	NP_001014591.1	CHDNT	138..191	CDD:462357
		TNG2	<282..422	CDD:227367
		PHD1_CHD_II	380..422	CDD:277006
		PHD2_CHD_II	440..482	CDD:277007
		CD1_tandem_CHD3-4_like	487..557	CDD:349314
		CD2_tandem_CHD3-4_like	610..664	CDD:349309	6/56 (11%)
		PLN03142	720..>1234	CDD:215601	175/608 (29%)
		DUF1087	<1292..1334	CDD:461922	10/43 (23%)
		CHDII_SANT-like	1380..1517	CDD:461920	5/19 (26%)
		CHDCT2	1757..1902	CDD:462358
RAD54	NP_188552.3	HepA	<180..679	CDD:440319	162/525 (31%)
		DEXHc_RAD54	180..421	CDD:350762	79/258 (31%)