|
Fly 105 RKEEKQAAKEKESASSGM-----------PSVEDVCSAFSVCNVE-----------IEYSEEELQ 147
:|:|||.:|.:....|.| ||..| ||.....|:| :..:|||..
Mouse 6 QKKEKQLSKLRALNHSPMSDASVNFDYKSPSPFD-CSPDQGENIEEAANHCLPHKNLYTTEEEAD 69
Fly 148 SLTTYKAFMHH-----------VRPILQKENPKIAAPKLVMLVAAKWREFCESNPHIQQEGGAAG 201
:|.:.|...|: |:...:|:.|. :|||....
Mouse 70 TLFSRKLTSHNGMEDSGGRGTGVKKKRKKKEPG------------------------EQEGTKGS 110
Fly 202 SGGSAGQARSVTGDEPEEPRSSRSSRNEKPDDIYEEAVEEEEEEEEEEKKPRRKRSGRGKKGRRP 266
........|.....||:|||.::..:..|. .:|.::::..||||:.|...|.|.
Mouse 111 KDREPKPKRKREPKEPKEPRRAKEPKRAKE--------PKETKQKDGVKKPRKHREASGTKE--- 164
Fly 267 SGKVPTLKIKLLGKRKRDSSDEEQDASGASERDSDLEFERMLQKSDDSADEKEAPVSSKADNSAP 331
||.||..:| ......|..
Mouse 165 ------------GKEKRSCTD-----------------------------------YGSRTKSKK 182
Fly 332 AAQDDGSGAPVVRKKAKTKIGNKFKKKNKLKKTKNFPEGEDGEHEHQDYCEVCQQGGEIILCDTC 396
|:::.|. .||.||| |.|:||:... |..|.:| :.
Mouse 183 ASREQGP-TPVERKK-------KGKRKNETTV-------ESLELDH-----------------SL 215
Fly 397 PRAYHLVCLEPELDEPPEGKWSCPHCEAD------GGAAEEEDDDEHQEFCRVCKDGGELLCCDS 455
| .|.|..|.| |...|| |...:....:|..:| :|..|.||.:....
Mouse 216 P--------NPSLQSPEE-----PSESADSQKRRSGRQVKRRKYNEDLDF-KVVDDDGETIAVLG 266
Fly 456 C--PSAYHTFCLNPPLDTIPDGDWRCPRCSCPPLTGKAEKIITWRWAQRSNDDGPSTSKGSKNSN 518
. .||.....|....:..|:.| ....|||:..:..|..:...|...
Mouse 267 AGRTSALSASTLAWQAEEPPEDD-----------ANIIEKILASKTVQEVHPGEPPFD------- 313
Fly 519 SRVREYFIKWHNMSYWHCEWVPEVQLDVHHPLMIRSFQRKYDMEEPPKFEESLDEADTRYKRIQR 583
:..:::|:.|.||.||:|....:| |:.|:..: :|:|
Mouse 314 --LELFYVKYRNFSYLHCKWATMEEL-----------------EKDPRIAQ----------KIKR 349
Fly 584 HKDKVGMKANDDAEVLEERFYKNGVKPEWLIVQRVINHRTARDGS-----TMYLVKWRELPYDKS 643
.::|.....:...|..|:.| .|:::.:.|::.....:|.. |.|||||..|||::|
Mouse 350 FRNKQAQMKHIFTEPDEDLF-----NPDYIEIDRILEVAHTKDAETGEEVTHYLVKWCSLPYEES 409
Fly 644 TWEEEGDDIQGLRQAIDYYQDLRAVCTSETTQSRSKKSKKGRKSKLKVEDDEDRPVKHYTPPPEK 708
|||.|.| :| ..|.|:....::..| |||. |:
Mouse 410 TWELEED--------VD-----------------PAKVKEFESLQILPE------VKHV----ER 439
Fly 709 PTTDLKKKYEDQPAFLEGTGMQLHPYQIEGINWLRYSWGQGIDTILADEMGLGKTIQTVTFLYSL 773
|.:|..:|.|....:.... :|..||:||:|||.::|....:.|||||||||||||::.||..:
Mouse 440 PASDAWQKLETSREYRNSN--RLREYQLEGMNWLLFNWYNRKNCILADEMGLGKTIQSIAFLSEI 502
Fly 774 YKEGHCRGPFLVAVPLSTLVNWEREFELWAPDFYCITYIGDKDSRAVIRENELSFEEGAIRGSKV 838
:..| ..||||:..||||:.||||||..|. :...|.|.|.:.||.:|::.|:.:.:. :|:.:
Mouse 503 FVRG-IHGPFLIIAPLSTITNWEREFRTWT-EMNAIVYHGSQISRQMIQQYEMVYRDA--QGNPL 563
Fly 839 SRLRTTQYKFNVLLTSYELISMDAACLGSIDWAVLVVDEAHRLKSNQSKFFRILNSYTIAYKLLL 903
|.: :||:|::|::|:|..|...|..|.|:.:::|||||||:...|....|....:.:|:||
Mouse 564 SGV----FKFHVVITTFEMILADCPELKKIHWSCVIIDEAHRLKNRNCKLLEGLKLMALEHKVLL 624
Fly 904 TGTPLQNNLEELFHLLNFLSRDKFNDLQAFQGEFADVSKEEQVKRLHEMLGPHMLRRLKTDVLKN 968
|||||||::||||.|||||...:|....||..||.|:..|||||:|..:|.|.||||||.||.||
Mouse 625 TGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGDLKTEEQVKKLQSILKPMMLRRLKDDVEKN 689
Fly 969 MPSKSEFIVRVELSAMQKKFYKFILTKNYEALNSKSGGGSC-SLINIMMDLKKCCNHPYLFPSAA 1032
:..|.|.|:.|||:.:|||:|:.||.||:..|...:...:. :|||.||:|:||||||||...|.
Mouse 690 LAPKQETIIEVELTNIQKKYYRAILEKNFSFLTKGANQHNMPNLINTMMELRKCCNHPYLINGAE 754
Fly 1033 E-------EATTAAGGLYEINSLTKAAGKLVLLSKMLKQLKAQNHRVLIFSQMTKMLDILEDFLE 1090
| :|.::....:::.::.:|||||||:.|:|.:|.|..|:|||||||.:.||||||:|.
Mouse 755 EKILEDFRKAHSSEASDFQLQAMIQAAGKLVLIDKLLPKLIAGGHKVLIFSQMVRCLDILEDYLI 819
Fly 1091 GEQYKYERIDGGITGTLRQEAIDRFNAPGAQQFVFLLSTRAGGLGINLATADTVIIYDSDWNPHN 1155
..:|.||||||.:.|.|||.|||||..|.:.:|||||.||||||||||..|||.||:||||||.|
Mouse 820 QRRYTYERIDGRVRGNLRQAAIDRFCKPDSDRFVFLLCTRAGGLGINLTAADTCIIFDSDWNPQN 884
Fly 1156 DIQAFSRAHRIGQANKVMIYRFVTRNSVEERVTQVAKRKMMLTHLVV----RPGMGGKGANFTKQ 1216
|:||.:|.|||||:..|.:||.:||||.|..:...|..|:.|...:: |.|........:|.
Mouse 885 DLQAQARCHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAILQDINRKGSTNGVQQLSKM 949
Fly 1217 ELDDILRFGTEDLFKEDDKEEAIHYDDKAVAELLDRTNRGIEEKESWANEYLSSFKVASYATKEE 1281
|::|:||.|...... |:::|...:.::.:.::|.|....|..:..... |:|..||:.....
Mouse 950 EVEDLLRKGAYGALM-DEEDEGSKFCEEDIDQILQRRTHTITIQSEGKG---STFAKASFVASGN 1010
Fly 1282 EEEEETEIIKQDAENSDPAY---WVKLLRHHYEQHQEDVGRSLGKGKRVRKQVNYTDGGVVAADT 1343
:.|....||.: |.|:.....|.:.|.....:.: .||||| |
Mouse 1011 ---------RTDISLDDPNFWQKWAKIAELDTEANNEKESLVIDR-PRVRKQ------------T 1053
Fly 1344 TRDDSNWQDNGSEYNSEYSAGSDEDGGDDDFDDQNGAERKAKRRLERRDDRPLPPLLARVGGNIE 1408
...:|..:|...|: ||..:.||| .....|||..|..|.|.....||..|:.
Mouse 1054 KHYNSFEEDELMEF-SELDSDSDE-------------RPTRSRRLSDRARRYLRAECFRVEKNLL 1104
Fly 1409 VLGF----------------NARQRKSFLNAIMRYGM------------------PPQD------ 1433
:.|: |.:..:....|::.|.: |.:|
Mouse 1105 IFGWGRWKDILTHGRFKWPLNEKDMEMICRALLVYCVKHYKGDEKIKSFIWELITPSKDGQVQTL 1169
Fly 1434 ---AFNSQWLVRDLRGKSERNFKAYVSLFMRHLCEPGADNAETFA----------DGVPREGLSR 1485
:..|..:.|..:||..:| .|..|...||:..| ||..:. .:
Mouse 1170 QNHSGLSAPVPRGRKGKKTKN----------QLLLPELKNADWLATCNPEVVLHDDGYKKH--LK 1222
Fly 1486 QH---VLTRIGVMSLIRKKVQEFEHINGYYSMP----ELILKPCEPVR----------------- 1526
|| ||.|:.::..::.::........:...| :::|...:.|.
Mouse 1223 QHCNKVLLRVRMLYYLKAEILGEAADKAFEGTPARELDVLLPDIDYVEIPVDWWDAEADKSLLIG 1287
Fly 1527 ---------SALKQDVAALEAPPTGGNVDKSATTSNSVTPATSAAPSPAPASEKGEDKDKDSEKE 1582
:|::.|.|.......|...:||.:....||..||..| |:|....:||.::
Mouse 1288 VFKHGYERYNAMRADPALCFLEKVGMPDEKSLSAEQGVTDGTSDIP------ERGNIDKEDSAED 1346
Fly 1583 K----DKTSAEKS--------EVKQEQEAEEDKKPGDVKQENPVEEAAGDTKPSDAEVKTEVAKT 1635
| .|.:|..| |.|.:.:|.:|....| |...||..|. .|.::..|...
Mouse 1347 KLDGLQKQTASPSDGSDGIFGEKKDDSQAAQDGSDPD-KSPWPVSSAL------TARLRRLVTIY 1404
Fly 1636 E--PKEETKDPE----------VKEE--PKTEEKE------------KEKVDDKKPIPPTTVIDD 1674
: .::|...|| |:|| .:|.|.: :|:.|..:.:....|:.|
Mouse 1405 QRCNRKELCRPEILGPGNQGYWVQEEVFRRTSEMDLINKEAQKRWTRREQADFYRTVSSFGVVYD 1469
Fly 1675 DDDDVMIVKEDGELEKPSASSPKDQKAVAAATSAATGATGKGAEDSLEVLKRKFMF---NIA--- 1733
:::||.............|.:::|||.....|:. |:.
Mouse 1470 ----------------------QEKKAFDWTQFRIISRLDKKSDESLEHYFYSFVAMCRNVCRLP 1512
Fly 1734 ---DGG--FTELHTLWLNEEKAAV-----------------------------PGREYEIWHR-- 1762
|.| ...::...:.||:||. |.....:|..
Mouse 1513 AWKDDGPPDASIYVEPITEERAAKTLYRIELLRKVREQVLMCPQLHERLQLCRPSLYLPVWWECG 1577
Fly 1763 RHDYWLLAGIVTHGYGRWQDIQNDIRFAIINEPFKMDVGKGNFLEIKNKFLARRFKLLEQA---L 1824
:||..||.|...||..|.. :.|:|:| :.:||:....: |:..:...|| |
Mouse 1578 KHDRDLLIGTAKHGLNRTD-------YYIMNDP------QLSFLDAYRNY-AQHKRTDTQAPGSL 1628
Fly 1825 VIEEQLRRAAYLNLAQDP-SHPAMSLNARFAEVECLAESHQHLSKESLAGNKPANAVLHKVLNQL 1888
....|.....|.:|...| |..:.||.:....:..:.....||.... |..| :......::::
Mouse 1629 CCLYQSNSKLYESLTYTPVSRTSESLESEPENLMRMESRDDHLCLPE--GGLP-DITCENFVSKV 1690
Fly 1889 EELLSDMKSDVSRLPATL 1906
:|::| :..|.:.||.:|
Mouse 1691 QEVIS-LDHDENLLPESL 1707
| 
