Protein Alignment Mi-2 and Lint-1

DIOPT Version :10

• Sequence 1: NP_001014591.1
• Gene: Mi-2 / 40170
• FlyBaseID: FBgn0262519
• Length: 1983
• Species: Drosophila melanogaster
• Sequence 2: NP_572692.1
• Gene: Lint-1 / 32055
• FlyBaseID: FBgn0030274
• Length: 602
• Species: Drosophila melanogaster
• Alignment Length: 520
• Identity: 113/520 - (21%)
• Similarity: 172/520 - (33%)
• Gaps: 141/520 - (27%)

  Fly    27 LSNDSDAPLKPNQNDEDDDYDPEDSRRKKKGKKRKTRKGEEKGRKKKKRKKNESEEDSDFVQHDE 91
            ||.|.|:.:.|.:..|.|:..|.......:|      .|::....|         .:.:::|.||
  Fly   151 LSQDDDSGMPPLKLSELDENIPLMLAPPVRG------LGQQIAAVK---------PEPEWLQGDE 200

  Fly    92 -EVEYP-----STSKRGRKRKEEKQAAKEKESASSGMPSVEDVCSAFSVCNVEIEYSEEELQSLT 150
             .|..|     |.||..:...:...|.:|..|.||..|                      |..:|
  Fly   201 ATVSVPPPPPQSKSKLMKGSLDSTPAKRENISRSSPPP----------------------LAPIT 243

  Fly   151 -TYKAFMHHVRPILQKENPKIAAPKLVMLVAAKWREFCESNPHIQQEGGAAGSGGSAGQARSVTG 214
             |..|.:..|.|..|.|:|.:           .:....:|..::||....|..  :..|.|....
  Fly   244 QTVVAELSQVPPSPQAESPPV-----------NFHVVAQSRKNLQQALRRARK--TKQQPRLFDD 295

  Fly   215 DEPEEPRSSRSSRNEK--------PDDIYEEAVEEEEEEEEEEKKPRRKRSGRGKKGR------- 264
            :|..|..|.::.||:.        |..:  |.......:..::..|:....|..|...
  Fly   296 EEDLEITSLQNDRNKNRTSDGKGTPPSL--EPTNAAANQAAKKTIPQMSSQGMAKNNTAKSKNTC 358

  Fly   265 RPSGKVPTLKIKLLGKRKRDSSDEEQDA---SGASERDSDLEFERMLQKSDDSADE-KEAPVSSK 325
            |.|...||            ||.:.|.|   ||:|: ||..|.::..|:...||.: ::.|..|:
  Fly   359 RKSSPTPT------------SSGQSQPAVSSSGSSD-DSSAELQQEQQRRVASAAQWRDEPRESR 410

  Fly   326 ADNSAPAAQDDGSG-----APVVRKKAKTKIGNKFKKKNKLKKTKN-----FPEGED-------- 372
            . ......|:...|     :|.|.||...:     ..|.|.:..:|     |..|:.
  Fly   411 T-QPEEYGQETFLGLFELYSPEVLKKLSQR-----HSKRKRRTVQNASGVDFHYGQQLNAVDALV 469

  Fly   373 ----GEHEHQDYCEVCQQGGEIILCDTCPRAYHLVCLEP-ELDEP--------PEGKWSCPHCE- 423
                |:.:.::..|......|..|.....|.|......| |:.|.        ..|..|...|:
  Fly   470 MGVRGQKKTKEKSEFLLSPTEKRLQANSKRTYTRKSKSPDEISEKSSAGGGSGASGTASSSACQH 534

  Fly   424 ADGGAAEEEDDDEHQEFCRVCKD--GGELLCCDSCPSAYHTFC----LNPPLDTIPDGDWRCPRC 482
            .||||::.....|    ||.||.  ..|.:.|..|...||..|    .|..|..:.:.  |||.|
  Fly   535 KDGGASKCRKCRE----CRECKRRVETEAMYCHLCSGLYHMDCHEFTKNRQLMQLQNS--RCPPC 593

  Fly   483  482
              Fly   594  593

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mi-2	NP_001014591.1	CHDNT	138..191	CDD:462357	10/53 (19%)
		TNG2	<282..422	CDD:227367	37/174 (21%)
		PHD1_CHD_II	380..422	CDD:277006	10/50 (20%)
		PHD2_CHD_II	440..482	CDD:277007	15/47 (32%)
		CD1_tandem_CHD3-4_like	487..557	CDD:349314
		CD2_tandem_CHD3-4_like	610..664	CDD:349309
		PLN03142	720..>1234	CDD:215601
		DUF1087	<1292..1334	CDD:461922
		CHDII_SANT-like	1380..1517	CDD:461920
		CHDCT2	1757..1902	CDD:462358
Lint-1	NP_572692.1	PHD	548..593	CDD:214584	15/46 (33%)