|
Fly 406 EPELDEPPEGKWSCPHCEADGGAAEEEDDDEHQEFCRVCKDGGELLCCDSCPSAYHTFCLNPPLD 470
:|:|| |..|.:....|||:::...|.|. :|..|.|..| || ....|......
Human 10 DPDLD---------PDVELEDAEEEEEEEEVAVEECD--RDDEEDLLDD--PS-LEGMCGTEHAQ 60
Fly 471 TIPDGDWRCPRCSCPPLTGKAEKIITWRWAQRSN--DDGPSTSKGSKNSNSRVREYFIKWHNMSY 533
...||. :.|||: ...:.::|.....|..|..| .:.|...:..|.|:.|..
Human 61 LGEDGQ-QPPRCT-STTSSQSEPSEQLRRHQGKNLASEDPKKKRAQKPSHMRRN----------- 112
Fly 534 WHCEWVPEVQLDVHHPLMIRSFQRKYDMEEPPKFEESLDEADTRYKRIQRHKD------------ 586
||...|: |..||.......:|.:.|.:..|:.||
Human 113 ------------------IRKLLRE-DQLEPVTKAAQQEELERRKRLEQQRKDYAAPIPTVPLEF 158
Fly 587 ---KVGMKANDDAEVLEERFYKNGVKPEWLIVQRVI---------NHRTARDGSTMYLVKWRELP 639
::.::|:|..:: |..::.|.|| :.:::|| |:
Human 159 LPEEIALRASDGPQL-----------PPRVLAQEVICLDSSSGSEDEKSSRD----------EV- 201
Fly 640 YDKSTWEEEGDDIQGLRQAIDYYQDLRAVCTSETTQSRSKKSKKGR---KSKLKVEDDEDRPVKH 701
.:.|:.||: .|..|.:||:.....::.:||. ...|...|...|.:.:
Human 202 IELSSGEED---------------TLHIVDSSESVSEDDEEEEKGGTHVNDVLNQRDALGRVLVN 251
Fly 702 YTPPPEKPTTDLKKKYEDQPAFLEGTGMQLHPYQIEGINWL---------RYSWGQGIDTILADE 757
...|||:....|..: ....:.|:||.||.:| |:....|...|||..
Human 252 LNHPPEEENVFLAPQ----------LARAVKPHQIGGIRFLYDNLVESLERFKTSSGFGCILAHS 306
Fly 758 MGLGKTIQTVTFLYSLYKEGHCRGPFLVAVPLSTLVNWEREFELWAPD----------------F 806
||||||:|.::|:..|::....: ..|..||::||.||..||.:|.|. |
Human 307 MGLGKTLQVISFIDVLFRHTPAK-TVLAIVPVNTLQNWLAEFNMWLPPPEALPADNKPEEVQPRF 370
Fly 807 YCITYIGDKD----SRAVIRENELSFEEGAI--RGSKVSRLRTTQYKF------NVLLTSYE-LI 858
:.:..:.|:. |||.:..:.:| ||.: .|.::.||.|.:..| .....|:. :|
Human 371 FKVHILNDEHKTMASRAKVMADWVS--EGGVLLMGYEMYRLLTLKKSFATGRPKKTKKRSHPVII 433
Fly 859 SMD--------------AACLGSIDWAVLVVDEAHRLKSNQSKFFRILNSYTIAYKLLLTGTPLQ 909
.:| |.|....| |::.||.||:|:.|:...:.|.:.....:::|||.|||
Human 434 DLDEEDRQQEFRREFEKALCRPGPD--VVICDEGHRIKNCQASTSQALKNIRSRRRVVLTGYPLQ 496
Fly 910 NNLEELFHLLNFLSRDKFNDLQAF---------QGEFADVSKEE-QVKR-----LHEMLGPHMLR 959
|||.|.:.:::|:..|.....|.| .|:..|.:.:: ::.| ||.:|...:.|
Human 497 NNLIEYWCMVDFVRPDFLGTRQEFSNMFERPILNGQCIDSTPQDVRLMRYRSHVLHSLLEGFVQR 561
Fly 960 RLKTDVLKNMPSKSEFIVRVELSAMQKKFYKFILTKNYEALNSKSGGGSCSLINIMMDLKKCC-- 1022
|..|.:..::|:|.|.::.|.||.:|:..| |:..:........|...| |.:.....||
Human 562 RGHTVLKIHLPAKEENVILVRLSKIQRDLY----TQFMDRFRDCGSSGWLGL-NPLKAFCVCCKI 621
Fly 1023 -NHPYLFPSAAEEATTA------------AG-----------GLYEINSLTKAAG---------- 1053
|||.:...|.::.:.| || |..|.::|..:.|
Human 622 WNHPDVLYEALQKESLANEQDLDVEELGSAGTSARCPPQGTKGKGEDSTLASSMGEATNSKFLQG 686
Fly 1054 -----------------------------------KLVLLSKMLKQLKAQNHRVLIFSQMTKMLD 1083
|:|||..::::......::|:|||....|.
Human 687 VGFNPFQERGNNIVTYEWAKDLLTNYQTGVLENSPKMVLLFHLIEESVKLGDKILVFSQSLSTLA 751
Fly 1084 ILEDFL-----------EGE-------QYKYERIDGGITGTLRQEAIDRFNAP-GAQQFVFLLST 1129
::|:|| ||: ...|.|:||......|:..|::||.| ....::|||||
Human 752 LIEEFLGKREVPCPPGTEGQGAQKWVRNISYFRLDGSTPAFERERLINQFNDPSNLTTWLFLLST 816
Fly 1130 RAGGLGINLATADTVIIYDSDWNPHNDIQAFSRAHRIGQANKVMIYRFVTRNSVEERV--TQVAK 1192
|||.||:||..|:.|:::|:.|||.:|.||..|.:|.||.....|||.|...::|::: .|::|
Human 817 RAGCLGVNLIGANRVVVFDASWNPCHDAQAVCRVYRYGQKKPCYIYRLVADYTLEKKIYDRQISK 881
Fly 1193 RKMMLTHLVV---RPGMGGKGANFTKQELDDILRFGTEDLFKEDDKEEAIHYDDKAVAELLDRTN 1254
:.| :..|| .|.: |||::|::::| |:.:|..|..:....
Human 882 QGM--SDRVVDDLNPML-----NFTRKEVENLL-----------------HFVEKEPAPQVSLNV 922
Fly 1255 RGIEEKESWANEYLSSFKVASYATKEEEEEEETEIIKQD-----AENSDPAYWVKLLRHHYEQHQ 1314
:||:|... .|:..|.....|||..|.|...:.::| ||. |..:..||:.:
Human 923 KGIKESVL----QLACLKYPHLITKEPFEHESLLLNRKDHKLTKAEK-------KAAKKSYEEDK 976
Fly 1315 EDVGRSLGKGKRVRKQVNYTDGGVVAADTTRDDS----------NWQDNGSEYNSEYSAGSDEDG 1369
|..|.||...........|.| |||....
Human 977 -------------RTSVPYTRPSYAQYYPASDQSLTSIPAFSQRNWQPTLK-------------- 1014
Fly 1370 GDDDFDDQNGAERKAKRRLERRDDRPLPPLLARVGGNIEVLGFNARQRKSFLNAIMRYGMPPQDA 1434
||: :..|..|..:....|:.|....:||::.............:|.:.|.|:..|..
Human 1015 GDE--------KPVASVRPVQSTPIPMMPRHVPLGGSVSSASSTNPSMNFPINYLQRAGVLVQKV 1071
Fly 1435 FNSQWLV------------RDLRGKSERNFKAYVSLFMRHLCEPGADNAETF---ADGVPREGLS 1484
..:..:| |...|:|....:.....::| ..:...| |.|.|:
Human 1072 VTTTDIVIPGLNSSTDVQARINAGESIHIIRGTKGTYIR------TSDGRIFAVRATGKPK---- 1126
Fly 1485 RQHVLTRIGVMSLIRKKVQEFEHI-NGYYSM-------PELILKPCEP----VRSALKQ--DVAA 1535
:...|.|:....:....|.. ||.:|. ||.:.:|..| :.|.|:| ||||
Human 1127 ----VPEDGRMAASGSQGPSCESTSNGRHSASSPKAPDPEGLARPVSPDSPEIISELQQYADVAA 1187
Fly 1536 LEAPPTGGNVDKSATTSNSVTPATSAA-PSPAPA 1568
|..|...:|:|:|| |.| ||
Human 1188 -------------ARESRQSSPSTNAALPGP-PA 1207
| 
