|
Fly 124 SVEDVCSAFSVCNVEIEYSEEELQSLTTYKAFMHHVRPILQKENPKIAAP-----KLVMLVAAKW 183
::.:...|..:.:||.|| ...|..||:....:..:..|:::.:|:.|.. ||..:...|:
Human 116 AIHEASRASQLVDVEKEY-RSVLDDLTSCTTSLRQINKIIEQLSPQAATSRDINRKLDSVKRQKY 179
Fly 184 ------REFCESNPHIQQEGGAAGSGGSAGQARSVTGDEPEEPRSSRSSRNEKPDDIYEEAVEE- 241
::......|:|...|.|........| |:..|....|.|..|......:..:||.:..
Human 180 NKEQQLKKITAKQKHLQAILGGAEVKIELDHA-SLEEDAEPGPSSLGSMLMPVQETAWEELIRTG 243
Fly 242 ------EEEEEEEEKKPRRKRSGRGKKGRRPSGKVPTLKIKLLGKRKRDSSDEEQDASGASERDS 300
.:..:::||||| ||.| .:|||..:..:
Human 244 QMTPFGTQIPQKQEKKPR--------------------KIML------------NEASGFEKYLA 276
Fly 301 D---LEFERMLQKSDDSADEK-EAPVSSKADNSAPAAQDDGSGAPVVRKKAKTKIGNKFKKKNKL 361
| |.|||..|..:..|..| .|||: |.|.......| .|||:. ..||:.:|
Human 277 DQAKLSFERKKQGCNKRAARKAPAPVT-------PPAPVQNKNKP--NKKARV----LSKKEERL 328
Fly 362 KKTKNFPEGEDGEHEHQDYCEVCQQGGEIILCDTCPRAYHLVCLEP-ELDEPPEGKWSCPHCEAD 425
|| |..:......|..|::.| |:| ..| |.|..||.:......|::
Human 329 KK-----------HIKKLQKRALQFQGKVGL----PKA-----RRPWESDMRPEAEGDSEGEESE 373
Fly 426 GGAAEEEDDDEHQEFCRVCKDGGELLCCDSCPSAYHTFCLNPPLDTIPDG-DWRCPRCSCPPLTG 489
....|||:::|..|. :|.| .|...|| |:..... |..|
Human 374 YFPTEEEEEEEDDEV-----EGAE-------------------ADLSGDGTDYELKPL---PKGG 411
Fly 490 KAEKIITWRWAQRSNDDGPSTSKGSKNSNSRVREYFIKWHNMSYWHCEWVPEVQLDVHHPLMIRS 554
|.:|.:. .|..:|| :|
Human 412 KRQKKVP---VQEIDDD-----------------FF----------------------------- 427
Fly 555 FQRKYDMEEPPKFEE----SLDEADTRYKRIQRHKDKVGMKANDDAEVLEERFYKNGVKPEWLIV 615
|...|| |:.|.....:::.|::|
Human 428 ---------PSSGEEAEAASVGEGGGGGRKVGRYRD----------------------------- 454
Fly 616 QRVINHRTARDGSTMYLVKWRELPYDKSTWEEEGDDIQGLRQAIDYYQDLRAVCTSETTQSRSKK 680
:||: |||: :..:..:|.
Human 455 --------------------------------DGDE--------DYYK--------QRLRRWNKL 471
Fly 681 SKKGRKSKLKVEDDEDRPVKHYTPPPEKPTTDLKKKYEDQPAFLEGTGMQLHPYQIEGINWLRYS 745
..:.::.:||:|||. |:...:..:.:: .|.|| ..:|..||..|:.||...
Human 472 RLQDKEKRLKLEDDS-----------EESDAEFDEGFK-VPGFL---FKKLFKYQQTGVRWLWEL 521
Fly 746 WGQGIDTILADEMGLGKTIQTVTFLYSL-YKEGHCR---------GPFLVAVPLSTLVNWEREFE 800
..|....||.||||||||||.:.||..| |.:...| ||.::..|.:.:..|.:||.
Human 522 HCQQAGGILGDEMGLGKTIQIIAFLAGLSYSKIRTRGSNYRFEGLGPTVIVCPTTVMHQWVKEFH 586
Fly 801 LWAPDFYCITYIGDKDSRAVIRENELSFEEGAIRGSKVSRLRTTQYKFNVLLTSYELISMDAACL 865
.|.|.| |..|.. |.|:....|...:|...:...:|:|||..|.:....:
Human 587 TWWPPF-----------RVAILH-----ETGSYTHKKEKLIRDVAHCHGILITSYSYIRLMQDDI 635
Fly 866 GSIDWAVLVVDEAHRLKSNQSKFFRILNSYTIAYKLLLTGTPLQNNLEELFHLLNFLSRDKFNDL 930
...||..:::||.|::::..:........:...::::|:|:|:||||.||:.|.:|:...|...|
Human 636 SRYDWHYVILDEGHKIRNPNAAVTLACKQFRTPHRIILSGSPMQNNLRELWSLFDFIFPGKLGTL 700
Fly 931 QAFQGEFA--------DVSKEEQVKR-------LHEMLGPHMLRRLKTDVLK--NMPSKSEFIVR 978
..|..:|: ..:...|||. |.:.:.|::|||:|:||.. ::|.|:|.::.
Human 701 PVFMEQFSVPITMGGYSNASPVQVKTAYKCACVLRDTINPYLLRRMKSDVKMSLSLPDKNEQVLF 765
Fly 979 VELSAMQKKFYK-FILTKN-YEALNSKSGGGSCSLINIMMDLKKCCNHPYLFPSAAEEATTAAGG 1041
..|:..|.|.|: |:.:|. |..|| |...:.:.::.|:|.||||.|| :||
Human 766 CRLTDEQHKVYQNFVDSKEVYRILN-----GEMQIFSGLIALRKICNHPDLF----------SGG 815
Fly 1042 LYEINSLT------------KAAGKLVLLSKMLKQLKAQNHRVLIFSQMTKMLDILEDFLEGEQY 1094
...:..|. |.:||::::..:||....|..|||:|||..:||||||.||..::|
Human 816 PKNLKGLPDDELEEDQFGYWKRSGKMIVVESLLKIWHKQGQRVLLFSQSRQMLDILEVFLRAQKY 880
Fly 1095 KYERIDGGITGTLRQEAIDRFNAPGAQQFVFLLSTRAGGLGINLATADTVIIYDSDWNPHNDIQA 1159
.|.::||..|...||..|.|:| .....|||||:||.||||:||..|:.|:|||.||||..|.||
Human 881 TYLKMDGTTTIASRQPLITRYN-EDTSIFVFLLTTRVGGLGVNLTGANRVVIYDPDWNPSTDTQA 944
Fly 1160 FSRAHRIGQANKVMIYRFVTRNSVEERVTQVAKRKMMLTHLVVRPGMGGKGANFTKQELDDILRF 1224
..||.||||..:|.:||.:|..::||::......|..||:.|::. .||. ||
Human 945 RERAWRIGQKKQVTVYRLLTAGTIEEKIYHRQIFKQFLTNRVLKD---------PKQR-----RF 995
Fly 1225 GTEDLFKEDDKEEAIHYDDKAVAELLDRTNRGIEEKESWANEYLSSFKVASYATKEEEEEEETEI 1289
||.:| .:::.:..:.:..:..||..
Human 996 -----FKSND-----------------------------------LYELFTLTSPDASQSTETSA 1020
Fly 1290 IKQDAENSDPAYWVKLLRHHYEQHQEDVGRSLGKGKRVRKQVNYTDGGVVAADTTRDDSNWQDNG 1354
|.. ...|| |:..:.|.::. :..:.|....|.|:..:....:...|.|..:...:..|
Human 1021 IFA-GTGSD----VQTPKCHLKRR---IQPAFGADHDVPKRKKFPASNISVNDATSSEEKSEAKG 1077
Fly 1355 SEYNSEYSAGSDEDGGDDDF------DDQNGAERKAKRRLERRDDRPLPPLLARVGGNIEVLGFN 1413
:|.|:..|..||....|... :|:.|.|..|... |..|:.:.||.|....:
Human 1078 AEVNAVTSNRSDPLKDDPHMSSNVTSNDRLGEETNAVSG---------PEELSVISGNGECSNSS 1133
Fly 1414 ARQRKSF----------LNAIMRYGMPPQDAFNSQWLVRDLRGKSERNFKAYVSLFMRHLCEPGA 1468
...:.|. |....:...|.|....:.|..:.: |.||..:.|....|
Human 1134 GTGKTSMPSGDESIDEKLGLSYKRERPSQAQTEAFWENKQM----ENNFYKHKSKTKHH------ 1188
Fly 1469 DNAETFADGVPREGLSRQHVL------------------TRIGVMSLIRK----------KVQEF 1505
.|..|....:|:. ||| ..|::| |.:..
Human 1189 --------SVAEEETLEKHLRPKQKPKNSKHCRDAKFEGTRI--PHLVKKRRYQKQDSENKSEAK 1243
Fly 1506 EHINGYYSMPELILKPCEPVRSALKQDVAALEAPPTGGNVDKSATTSNSVTP------------- 1557
|..|..|.: |.:.|....|.|.:|.|.....|.|....|:..| |.|..
Human 1244 EQSNDDYVL-EKLFKKSVGVHSVMKHDAIMDGASPDYVLVEAEA---NRVAQDALKALRLSRQRC 1304
Fly 1558 --ATSAAP--------SPAPASEKGEDKDKDSEKEKDKTSAEKSEVKQEQEAEED---KKPGDVK 1609
|.|..| |.|||.: |.:..:|.....|.:........|..:| ||.|
Human 1305 LGAVSGVPTWTGHRGISGAPAGK----KSRFGKKRNSNFSVQHPSSTSPTEKCQDGIMKKEG--- 1362
Fly 1610 QENPVEEAAGDTKPSDAE-----VKTEVAKTEPKEETKDPEVKEEPKTEEKEKEKVDDKKPIPPT 1669
::|..|..:|..:.:|:. ..:.:||...:.....|| ..|.|...:.:...:.||
Human 1363 KDNVPEHFSGRAEDADSSSGPLASSSLLAKMRARNHLILPE------RLESESGHLQEASALLPT 1421
Fly 1670 TVIDDDDDDVMI---------VKEDGELEKPSASSPKDQKAVAAATSAATGATGKGAEDSLEVLK 1725
| :.||::: ...||: ||:.:..:...:..||:.....: |:|:
Human 1422 T----EHDDLLVEMRNFIAFQAHTDGQ-----ASTREILQEFESKLSASQSCVFR------ELLR 1471
Fly 1726 RKFMFNIADGG 1736
....|:...||
Human 1472 NLCTFHRTSGG 1482
| 
