Protein Alignment Rab8 and Rab27b

DIOPT Version :10

• Sequence 1: NP_524172.1
• Gene: Rab8 / 40168
• FlyBaseID: FBgn0262518
• Length: 207
• Species: Drosophila melanogaster
• Sequence 2: NP_085031.3
• Gene: Rab27b / 80718
• MGIID: 1931295
• Length: 218
• Species: Mus musculus
• Alignment Length: 202
• Identity: 88/202 - (43%)
• Similarity: 135/202 - (66%)
• Gaps: 18/202 - (8%)

  Fly     5 YDYLFKLLLIGDSGVGKTCILFRFSEDAFNTTFISTIGIDFKIRTIELDNK----------KIKL 59
            ||||.|||.:||||||||..|:|::::.||..||:|:||||:.:.:..|.:          |:.|
Mouse     6 YDYLIKLLALGDSGVGKTTFLYRYTDNKFNPKFITTVGIDFREKRVVYDTQGADGASGKAFKVHL 70

  Fly    60 QIWDTAGQERFRTITTAYYRGAMGIMLVYDITQEKSFENIKNWIRNIEENA---SADVEKMLLGN 121
            |:||||||||||::|||::|.|||.:|::|:|.::||.|::||:..::.||   :.|:  :|:||
Mouse    71 QLWDTAGQERFRSLTTAFFRDAMGFLLMFDLTSQQSFLNVRNWMSQLQANAYCENPDI--VLIGN 133

  Fly   122 KCELTDKRQVSKERGEQLAIEYGIKFMETSAKASINVEEAFLTLASDIKAKTEKRMEANNPP--- 183
            |.:|.|:|:|::.:..:||.:|||.:.||||....|||::..||...|..:.||.:|....|
Mouse   134 KADLPDQREVNERQARELAEKYGIPYFETSAATGQNVEKSVETLLDLIMKRMEKCVEKTQVPDTV 198

  Fly   184 KGGHQLK 190
            .||:..|
Mouse   199 NGGNSGK 205

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab8	NP_524172.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	80/178 (45%)
Rab27b	NP_085031.3	Rab27A	6..185	CDD:206700	81/180 (45%)
		Effector region. /evidence=ECO:0000250	38..46		5/7 (71%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..218		4/12 (33%)