Protein Alignment Rab8 and RAB8A

DIOPT Version :10

• Sequence 1: NP_524172.1
• Gene: Rab8 / 40168
• FlyBaseID: FBgn0262518
• Length: 207
• Species: Drosophila melanogaster
• Sequence 2: NP_005361.2
• Gene: RAB8A / 4218
• HGNCID: 7007
• Length: 207
• Species: Homo sapiens
• Alignment Length: 207
• Identity: 164/207 - (79%)
• Similarity: 183/207 - (88%)
• Gaps: 0/207 - (0%)

  Fly     1 MAKTYDYLFKLLLIGDSGVGKTCILFRFSEDAFNTTFISTIGIDFKIRTIELDNKKIKLQIWDTA 65
            |||||||||||||||||||||||:||||||||||:||||||||||||||||||.|:|||||||||
Human     1 MAKTYDYLFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQIWDTA 65

  Fly    66 GQERFRTITTAYYRGAMGIMLVYDITQEKSFENIKNWIRNIEENASADVEKMLLGNKCELTDKRQ 130
            ||||||||||||||||||||||||||.||||:||:||||||||:||||||||:|||||::.||||
Human    66 GQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMILGNKCDVNDKRQ 130

  Fly   131 VSKERGEQLAIEYGIKFMETSAKASINVEEAFLTLASDIKAKTEKRMEANNPPKGGHQLKPMDSR 195
            |||||||:||::||||||||||||:||||.||.|||.|||||.:|::|.|:|......:|....:
Human   131 VSKERGEKLALDYGIKFMETSAKANINVENAFFTLARDIKAKMDKKLEGNSPQGSNQGVKITPDQ 195

  Fly   196 TKDSWLSRCSLL 207
            .|.|...||.||
Human   196 QKRSSFFRCVLL 207

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab8	NP_524172.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	146/165 (88%)
RAB8A	NP_005361.2	Rab8_Rab10_Rab13_like	6..172	CDD:206659	146/165 (88%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P62820	31..45		12/13 (92%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P62820	63..80		16/16 (100%)