Protein Alignment Rab8 and RAB12

DIOPT Version :10

• Sequence 1: NP_524172.1
• Gene: Rab8 / 40168
• FlyBaseID: FBgn0262518
• Length: 207
• Species: Drosophila melanogaster
• Sequence 2: NP_001020471.3
• Gene: RAB12 / 201475
• HGNCID: 31332
• Length: 340
• Species: Homo sapiens
• Alignment Length: 168
• Identity: 82/168 - (48%)
• Similarity: 125/168 - (74%)
• Gaps: 1/168 - (0%)

  Fly     6 DYLFKLLLIGDSGVGKTCILFRFSEDAFNTTFISTIGIDFKIRTIELDNKKIKLQIWDTAGQERF 70
            |:..::::||..|||||.::.||::|.|.....||:|:||||:|:||..|||:||||||||||||
Human   136 DFKLQVIIIGSRGVGKTSLMERFTDDTFCEACKSTVGVDFKIKTVELRGKKIRLQIWDTAGQERF 200

  Fly    71 RTITTAYYRGAMGIMLVYDITQEKSFENIKNWIRNIEENASADVEKMLLGNKCELTDKRQVSKER 135
            .:||:||||.|.||:||||||::::|:::..|::.|::.||.|.|.:|:|||.:....|::::::
Human   201 NSITSAYYRSAKGIILVYDITKKETFDDLPKWMKMIDKYASEDAELLLVGNKLDCETDREITRQQ 265

  Fly   136 GEQLAIEY-GIKFMETSAKASINVEEAFLTLASDIKAK 172
            ||:.|.:. |::|.|.|||.:.||:|.||.|..||..|
Human   266 GEKFAQQITGMRFCEASAKDNFNVDEIFLKLVDDILKK 303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab8	NP_524172.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	81/166 (49%)
RAB12	NP_001020471.3	Rab12	139..340	CDD:206699	81/165 (49%)