DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Deaf1 and gmeb2

DIOPT Version :9

Sequence 1:	NP_001262069.1	Gene:	Deaf1 / 40164	FlyBaseID:	FBgn0013799	Length:	576	Species:	Drosophila melanogaster
Sequence 2:	XP_009295385.1	Gene:	gmeb2 / 568906	ZFINID:	ZDB-GENE-090313-149	Length:	501	Species:	Danio rerio

Alignment Length:	290	Identity:	57/290 - (19%)
Similarity:	116/290 - (40%)	Gaps:	59/290 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   210 SENPSTQHNEVFQIRCKTTCAELYRSKLGSGGRG-RCVKYKDKWHTPSEFEHVCGRGSSKDWKRS 273
            |::...:.:.::.|.|..:.|.|...|....|.. :||:..:...:|.||.::.|:.:.|||||:
Zfish    75 SDDTDVEGDILYPITCGDSKANLVWKKFVCPGINIKCVQLNEHLISPKEFVYIAGKSTLKDWKRA 139

  Fly   274 IKYGGKSLQSLIDEGTLT--PHATNCSCTVCCDDEAGESASGPVRLFTPYKRRKRNQTDLDM--- 333
            |:..|..|:.::|.|.|.  .|:..||.|  |                       ..|.:|:
Zfish   140 IRLNGTMLRKIMDSGELDFYQHSRLCSNT--C-----------------------RSTKIDLVGS 179

  Fly   334 ESGPKRKRNTHHSNNNNSNTNNNNTSGSGANNCVDVTAAVAAATASVVDENNMFLSEENITSKDE 398
            ......:::|..:....::|:.|.:|.|.:.:..|.|..|.|            :.|:.:|.
Zfish   180 RGSLSSQQSTETAPATPASTDVNGSSSSFSTDVEDSTEWVTA------------IGEDTMTF--- 229

  Fly   399 PWAALNDS---LDTSTELVDQSQ--MGNTYER-ETFVVNINDGSSIAVLDTSQSMKNIEHVYCTM 457
             |..|.|:   .|...:|..:.|  :....|| :...:.:.|.:.:..:..:..|.::      :
Zfish   230 -WRGLKDAGMLEDVMEDLQKEIQEILKGLEERIQDPPLQVKDAALLNNIVQNFGMLDL------V 287

  Fly   458 VKATNDFKRMLNDMKQSFERRIEVLQKERD 487
            .|.....|..::..::.:.|.:..|:::.|
Zfish   288 KKVLASHKSQMDRCREQYTRSLVALEQQCD 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Deaf1	NP_001262069.1	SAND	219..291	CDD:128554	22/72 (31%)
Deaf1	NP_001262069.1	zf-MYND	521..557	CDD:280009
gmeb2	XP_009295385.1	SAND	81..156	CDD:279658	22/74 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4333
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900