Protein Alignment Deaf1 and Gmeb2

DIOPT Version :10

• Sequence 1: NP_524169.1
• Gene: Deaf1 / 40164
• FlyBaseID: FBgn0013799
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_937812.1
• Gene: Gmeb2 / 229004
• MGIID: 2652836
• Length: 530
• Species: Mus musculus
• Alignment Length: 387
• Identity: 77/387 - (19%)
• Similarity: 142/387 - (36%)
• Gaps: 102/387 - (26%)

  Fly   135 KTIVIQQQQTQPGGGGGGANNAGTNTTATNTIGLNHDGSGSNNSHDSLATLEHAAGGASGVGGGG 199
            :.:|:....|...|       :|.....|..:..|....|.:.:.|::.| |:||..|:.
Mouse    12 EVVVVTTPDTAVDG-------SGVEEVKTVLVTTNLAPHGGDLTEDNMET-ENAAAAAAA----- 63

  Fly   200 GGTGGGSSGWSENPSTQHNE-----------------VFQIRCKTTCAEL-YRSKLGSGGRGRCV 246
                      :...|:|..|                 |:.|.|..:.|.| :|..:..|...:||
Mouse    64 ----------AFTASSQLKEAVLVKMAEEGENLEAEIVYPITCGDSRANLIWRKFVCPGINVKCV 118

  Fly   247 KYKDKWHTPSEFEHVCGRGSSKDWKRSIKYGGKSLQSLIDEGTLTPHATNCSCTVCCDDEAGESA 311
            :|.:...:|.||.|:.|:.:.|||||:|:..|..|:.::|.|.|..:..:..|:..|.....:.:
Mouse   119 QYDEHVISPKEFVHLAGKSTLKDWKRAIRMNGIMLRKIMDSGELDFYQHDKVCSNTCRSTKIDLS 183

  Fly   312 SGPVRLFTPYKRRKRNQTDLDMESGPKRKRNTHHSNNNNSNTNNNNTSGSGANNCVDVTAAVAAA 376
            ...|.|.:|                    .:|.:.....:..:.|   ||.|...::........
Mouse   184 GARVSLSSP--------------------TSTEYIPLTPAAADVN---GSPATITIETCEDPGDW 225

  Fly   377 TASVVDENNMFLSEENITSKDEPWAALNDS--LDTSTELVD--QSQMGNTYE------------- 424
            |.::.|:...|            |..|.|:  ||   |::.  |.::..|.:
Mouse   226 TTTIGDDTFAF------------WRGLKDAGLLD---EVIQEFQQELEETMKGLQQRVQDPPLQL 275

  Fly   425 RETFVVNINDGSSIAVLDTSQSMKNIEHVYCTMVKATNDFKRMLNDMKQSFE---RRIEVLQ 483
            |:..::| |...:..:||..:  |.:....|.|.::...:.|.|..::|..:   ||.:.|:
Mouse   276 RDAVLLN-NIVQNFGMLDLVK--KVLASHKCQMDRSREQYARDLAALEQQCDEHRRRAKELK 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Deaf1	NP_524169.1	SAND	219..291	CDD:128554	26/89 (29%)
		zf-MYND	521..557	CDD:460312
Gmeb2	NP_937812.1	SAND	90..163	CDD:128554	25/72 (35%)