Protein Alignment verm and ChLD3

DIOPT Version :10

• Sequence 1: NP_001163469.1
• Gene: verm / 40149
• FlyBaseID: FBgn0261341
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: XP_061516705.1
• Gene: ChLD3 / 1277832
• VectorBaseID: AGAMI1_003509
• Length: 525
• Species: Anopheles gambiae
• Alignment Length: 557
• Identity: 243/557 - (43%)
• Similarity: 330/557 - (59%)
• Gaps: 52/557 - (9%)

  Fly     8 LSVVCLCLAV-------DGLYVKNSFEPAIDQDPSRRYQRKPHGQDKLEGVDVEEVCADRPADEY 65
            |....|.|||       .|..||.|.:..:......|:.|.|                |||.
Mosquito     5 LCYTLLTLAVTFTGNAHGGNLVKRSLKNTVLCLEDGRFYRNP----------------DRPE--- 50

  Fly    66 FRLETDGDCREVYRCDSAGEDGTWRLAPIRCAGGLAFDVLRQLCDWKSNVKSCDVLEKPRKAKPI 130
            .::.|:.:|.:.|.|    .||  .:...:|:.||.|||.||:||:|.||.:|||..:.|..||:
Mosquito    51 HKMWTNAECAKYYLC----LDG--EVFEFKCSVGLLFDVSRQICDFKQNVDNCDVTAEKRVPKPL 109

  Fly   131 LKTDEPICPE-GKLSCGDGECLDKELFCNGKSDCKDESDENACSVDEDPNRAPECDPTQCALPDC 194
            |:..:  |.| .:|.||||.||..|.||:|..||:|.|||..|.|:.|||.|..||.:.|.||||
Mosquito   110 LENAK--CEERSQLGCGDGTCLPNEYFCDGSVDCEDGSDEGWCDVENDPNAADPCDLSVCELPDC 172

  Fly   195 FCSADGTRIPGGIEPQQVPQMITITFNGAVNVDNIDLY-EDIFNGQRQNPNGCSIKGTFFVSHKY 258
            |||.|||.|||.:|....|||:.:||:.|:|.:|.:|| |.||...|:|||||.|:.|||:||:|
Mosquito   173 FCSKDGTVIPGRLERYHTPQMVLLTFDDAINFENWELYTEKIFTPGRKNPNGCPIRATFFISHQY 237

  Fly   259 TNYSAVQDLHRRGHEISVFSLTHKDDPNYWT-GGSYDDWLAEMAGSRLIVERFANITDGSIIGMR 322
            |||:.||.....||||:|.|:||:....:|: ..:.:||..||.|...|:.||:|:....:.|||
Mosquito   238 TNYAQVQRAWNDGHEIAVHSITHRGPEEWWSRNATIEDWFDEMVGQANIINRFSNVRMEELRGMR 302

  Fly   323 APYLRVGGNKQFEMMADQFFVYDASITASLGRVPIWPYTLYFRMPHKCNGNAHNCPSRSHP-VWE 386
            .|:||||.|:||.||.:..||||:|:.|.....|:|||||.::|||.||||...|||||:| :||
Mosquito   303 VPFLRVGWNRQFLMMKEFGFVYDSSMVAPFSNPPLWPYTLDYKMPHACNGNNQYCPSRSYPGIWE 367

  Fly   387 MVMNELDRRDDPTFDESLPGCHMVDSCSNVASGDQFARLLRHNFNRHYNSNRAPLGLHFHASWLK 451
            :|||:|:..:..        |.|||:|....:|:...|:..|||.|||:||||||||:||::|.:
Mosquito   368 LVMNQLEAGEYT--------CGMVDTCPPHMNGEDVYRMFVHNFKRHYHSNRAPLGLYFHSTWFR 424

  Fly   452 SKKEYRDELIKFIEEMLGRNDVFFVTNLQVIQWMQNPTELNSLRDFQEWK---EKCDVKGQPYCS 513
             |:||.|..::|:::|....||:||||.|.|:||:|||..|.|..|:.|:   ::.|.:.|. |:
Mosquito   425 -KQEYLDAFLRFLDDMAKYPDVYFVTNHQAIEWMRNPTTSNQLGHFEPWQCRPKQLDPQEQA-CN 487

  Fly   514 LPNACPLTTRELPGETLRLFTCMECPNNYPWILDPTG 550
            ||..|.|.:|.|..:.. |.||.|||..||||.:..|
Mosquito   488 LPRTCKLHSRVLQQDRY-LSTCNECPAQYPWIRNEFG 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
verm	NP_001163469.1	CBM_14	57..118	CDD:426342	22/60 (37%)
		LDLa	138..172	CDD:238060	19/34 (56%)
		CE4_CDA_like_1	213..488	CDD:200596	133/277 (48%)
ChLD3	XP_061516705.1	None