Protein Alignment l(3)76BDm and TRS85

DIOPT Version :10

• Sequence 1: NP_649135.2
• Gene: l(3)76BDm / 40140
• FlyBaseID: FBgn0260655
• Length: 1319
• Species: Drosophila melanogaster
• Sequence 2: NP_010393.3
• Gene: TRS85 / 851686
• SGDID: S000002515
• Length: 698
• Species: Saccharomyces cerevisiae
• Alignment Length: 797
• Identity: 136/797 - (17%)
• Similarity: 249/797 - (31%)
• Gaps: 286/797 - (35%)

  Fly    11 ARDIIRNIFSPLIGVLSSPQAD---------------------------------------EIC- 35
            |:.||.|..:|:|.|.|:|..|                                       |:|
Yeast    27 AKRIISNAIAPVITVTSTPLFDKHIQETYKVDSLYMLLRFFGGCVSDRDQANEAKVGQHEHEVCD 91

  Fly    36 ---------HRNNLSFVELLQPFAKLPNDAHFRDVSGTSVSVRGLRLNFCDVDWRPPQTILARKM 91
                     ...||....|.:..::..:::.|:..|..|..:|..         ||...::..:.
Yeast    92 ASDSTDSIPKNKNLEVPNLSKKGSRSRSNSLFQRDSTQSQYIRFT---------RPLGDLIETRD 147

  Fly    92 LNESVTNAHN-----DKTRLATIAGIDLELPTS---------------------EPWFEQWRETF 130
            .|:.:.|.|:     |.......|..|..:|.:                     .|:     |||
Yeast   148 ANDMLFNYHSLEVFLDNYLKLVAANTDEMVPHNLLKKSIYHSFFSLAISSTNNLSPY-----ETF 207

  Fly   131 LTVQFPADHEFTRHLLSCLLVLSSADPQIVETAHKLGQRVQQMQSITPQKLPKWFHPTEVLNSYV 195
                        .|.:..|:.|..::.::.|.|..|....:.:...| :..|.:.:..|:|..::
Yeast   208 ------------NHPILSLIALDISNGEVYEDARDLLVNFKNLNHNT-ENFPIFMNTNEMLPVFL 259

  Fly   196 VLH-EASQGDLSKAQQ-GFELLKSTFGDSKCFLVSINSMDSQGAAEVPDHWA-TFIKRQPKSDPN 257
            :.: :.||.:..|.|. ..:|.|..|.:|  .|:::              |. :||     .|.|
Yeast   260 LCYNDDSQEEFEKCQALAKKLKKQLFVES--ILLAL--------------WKDSFI-----YDEN 303

  Fly   258 LPSTDLSAPKSPQEAVSVISMPAMQMSQLLEGVSAQDSDLAMLHPLSPMQESATEA-INSKFSIS 321
                            |||.:....||.|.|         .:....:|.|.:.:.| |||.:
Yeast   304 ----------------SVIQLHQPVMSSLEE---------ILFFLQAPTQTTLSLALINSIY--- 340

  Fly   322 SESIASQTINPNVWGNELEADAPHGGCLTSRDIDNLRHFVQDYAVRALIPYIEHLVAILAEGVTN 386
                                             |.|.:.|.|    .:||:::..|:...|.:..
Yeast   341 ---------------------------------DMLDYLVYD----LMIPFMKRKVSFWEETILQ 368

  Fly   387 KKGVSKSLLSATK--RWFVTSKPGAGANNQNAV--------IYTNESAELQTRKLGDLYFMFGHY 441
            .:   |||.:..|  :.|:...|..|.:..|::        .:.:.|:|...|||.|...|...:
Yeast   369 PR---KSLFNGAKFFKKFMNKNPVNGNHQHNSLTRDSQGNEYFASSSSEFLMRKLADWSMMLSDF 430

  Fly   442 NLAFQSYHQAKRDFNADSAWQYYAGALEMAALSAFM----LGTAQRKTYD---YMEDAIVCYLTV 499
            ..|:.:|.....|.  |:..:|.|..:|..|:|..|    :.|.:....|   .:|.|:..|...
Yeast   431 KTAYSTYESLMDDL--DAFPKYLASCIEWCAVSLLMGAQSIVTVKMIKNDINPLIERALATYENC 493

  Fly   500 CKLQQ-----------------FATRATLLSME---CLKTARLYSEVAKQLIRMTNEESDL---R 541
            .::|:                 :.||..:|:.|   .|......:..|.|.:....:|..|   .
Yeast   494 SRIQRGKGKESNSLDVTEPVRSYETRCMILASELFLSLSNTWTSTPYAIQYLETILDECKLGPCS 558

  Fly   542 SALLLEQAAYCFLVTQPP-----------------------------------------MHRKYA 565
            ..::.|:.:.|:.:...|                                         ..||.|
Yeast   559 QIMVWERLSDCYNLRVDPRIKHRVGAMKKDAKDTEDLRGEHKYSTDHFTDEDILSEGLTRRRKAA 623

  Fly   566 FHIVLAGNRYSRAGQRKHAYRCYRQAYQVFQKREWSLAEDHIQYTVAKQAYMLKQLEEASRSFAH 630
            |..::|..:::...|.:....|.:.....:.:.:: |..:.:..:..|....||.::.|.
Yeast   624 FFRLIAAKKWAEQKQWRQVSWCLKDIESTYSEIKF-LHGNGLILSKLKNQLNLKDVDSAP----- 682

  Fly   631 LLRPGSLQSAQQQTSFL 647
              ||......:...||:
Yeast   683 --RPSEKNLTRTSVSFI 697

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(3)76BDm	NP_649135.2	TRAPPC-Trs85	160..608	CDD:463688	93/532 (17%)
TRS85	NP_010393.3	TRAPPC-Trs85	225..666	CDD:463688	93/533 (17%)