Protein Alignment l(3)76BDm and l(3)76BDm

DIOPT Version :10

• Sequence 1: NP_649135.2
• Gene: l(3)76BDm / 40140
• FlyBaseID: FBgn0260655
• Length: 1319
• Species: Drosophila melanogaster
• Sequence 2: XP_308792.5
• Gene: l(3)76BDm / 1270120
• VectorBaseID: AGAMI1_003634
• Length: 1342
• Species: Anopheles gambiae
• Alignment Length: 1361
• Identity: 640/1361 - (47%)
• Similarity: 885/1361 - (65%)
• Gaps: 79/1361 - (5%)

  Fly     1 MLHLTGQSYNARDIIRNIFSPLIGVLSSPQADEICHRNNLSFVELLQPFAKLPNDAHFRDVSGTS 65
            |:|||||:|:.::||:|||||::|.:.|.||:|:|.:|||||||:||||.||.:||||||::|||
Mosquito     1 MIHLTGQNYSTKEIIQNIFSPMVGAIVSQQAEELCQKNNLSFVEMLQPFLKLSSDAHFRDIAGTS 65

  Fly    66 VSVRGLRLNFCDVDWRPPQTILARKMLNESVTNA-HNDKTRLATI-AGIDLELPTSEPWFEQWRE 128
            ||::|||:|..||:|||||||||:|||||:||.| ..||.|...: .|..:::|.||||||||||
Mosquito    66 VSIKGLRINVVDVNWRPPQTILAKKMLNEAVTTAPGGDKMRAIKLDDGSFVDIPVSEPWFEQWRE 130

  Fly   129 TFLTVQFPADHEFTRHLLSCLLVLSSADPQIVETAHKLGQRVQQMQSITPQKLPKWFHPTEVLNS 193
            ||||||||||||||||||..|:|:||.||..:|||.:|.:::|.||:|||.:||||| .::.||.
Mosquito   131 TFLTVQFPADHEFTRHLLCSLIVVSSIDPNPIETASQLTKKIQMMQNITPPRLPKWF-ASDALNC 194

  Fly   194 YVVLHEASQGDLSKAQQGFELLKSTFGDSKCFLVSINSMDSQGAAEVPDHWATFIKRQPKSDPNL 258
            ||:||:...||:.||||.||.||||:|:.||||:.|||.... ..:.||.|..::|:..:|:|:.
Mosquito   195 YVMLHDGCSGDIGKAQQAFEGLKSTYGEHKCFLLQINSHGGP-PTDCPDPWVRYLKKHQRSEPST 258

  Fly   259 PSTDLSAPKSPQEAVSVISMP--AMQMSQLL---EGVSAQDSDLA-------------MLHPLSP 305
            .|...||||:||:..||..||  .:|.|.||   .|:|:..|.|:             :.|||||
Mosquito   259 ASDVDSAPKTPQDMGSVTGMPTTVVQSSNLLVHGGGISSSGSSLSSETPPSGIVVGEVIAHPLSP 323

  Fly   306 MQESATE-AINSKFSISSESIASQTINPNVWGNELEADAPHGGCLTSRDIDNLRHFVQDYAVRAL 369
            :||:..| ...|..:.|.:|::.||||||||..|.:.:..||..||:.|:|||:|||||:|||||
Mosquito   324 VQETGIELQETSSLTSSIDSLSLQTINPNVWPIESDIEVAHGSFLTAGDLDNLKHFVQDFAVRAL 388

  Fly   370 IPYIEHLVAILAEGVTNKKGVSKSLLSATKRWFVTSKPGAGANNQNAVIYTNESAELQTRKLGDL 434
            |||:|.||.:|.:.::||||||:||||||||||||:|||.. .|||||:|||||.||||||||||
Mosquito   389 IPYVERLVGVLNDSISNKKGVSRSLLSATKRWFVTNKPGVN-TNQNAVVYTNESTELQTRKLGDL 452

  Fly   435 YFMFGHYNLAFQSYHQAKRDFNADSAWQYYAGALEMAALSAFMLGTAQRKTYDYMEDAIVCYLTV 499
            ||||.||:||||:||||||||||||||||||||||||||:|.|.|||.||||||||:||:.||..
Mosquito   453 YFMFSHYSLAFQAYHQAKRDFNADSAWQYYAGALEMAALAAHMQGTASRKTYDYMEEAILTYLNS 517

  Fly   500 CKLQQFATRATLLSMECLKTARLYSEVAKQLIRMTNEESDLRSALLLEQAAYCFLVTQPPMHRKY 564
            |||.||||||||||||||:.|:.|:|.||||||||:|:||||||||||||:||||:..||.:|||
Mosquito   518 CKLPQFATRATLLSMECLRAAKQYNEAAKQLIRMTSEDSDLRSALLLEQASYCFLLANPPQYRKY 582

  Fly   565 AFHIVLAGNRYSRAGQRKHAYRCYRQAYQVFQKREWSLAEDHIQYTVAKQAYMLKQLEEASRSFA 629
            |.|.||||:|:|:.|||||::|.|:||||||:.|.|||||||||||:.:||..||:|:|||....
Mosquito   583 ALHCVLAGHRFSKVGQRKHSFRTYKQAYQVFENRGWSLAEDHIQYTIGRQASNLKKLDEASLCLE 647

  Fly   630 HLLRPGSLQSAQQQTSFLKEYIQTQNELVKRSPE-LGLLPH-ALPQVVQSSVRVLTLVQSPSAVA 692
            |||||.|:|:|.|||.||:||:.|:..|..:..| ...:|. |||::||:..:||.....|.:..
Mosquito   648 HLLRPSSMQTATQQTLFLREYLSTKKALQAKGGEGANDIPSIALPKIVQTMTKVLVTSPPPVSNP 712

  Fly   693 PHVPATNIDINSNLTADEPIWNKIEEMLVITAANNKPFVFKPSRYLYTKQQPALETPVAVQGEPI 757
            .||.||||:|.:..| ||.:|||:|||||.:||.....||:||:.|::.:.||.|.|.:|.||||
Mosquito   713 LHVAATNINITATPT-DENVWNKMEEMLVQSAAERPVMVFRPSKSLFSTEAPATENPRSVHGEPI 776

  Fly   758 ELAVTLSNSVQCRIALSEIDLLWKLTLDNDEVLSNA------CTYEESSDSANKIAVGAAIKTSC 816
            |:|..|.|:::..:....|:|||:...:..|:.||.      .:.||.|:..|.:|      :|.
Mosquito   777 EVAFNLENTIKPAVLFENINLLWEFRRETGEIFSNRPLFLGDVSLEERSEIENVVA------SSF 835

  Fly   817 MASIKLAEQAEETLHFKLTPKLTGRLSILGVVCRVA----AGADPAASLLGTLQFETQKIRPHN- 876
            :|.:...|...:||..||||:.||:|.|||:|.:::    ||:..|.||.|...||.|.||..:
Mosquito   836 VALVTFGEHETKTLVLKLTPRSTGQLRILGIVGKISAAQPAGSGEAPSLWGKQLFEAQPIRVGSA 900

  Fly   877 -----------AKQSSQTVMDNRLTIKLVPQLPAMNVSFTPVPNRLLAGEIVPVHVTLRNMGIAP 930
                       |..|:....|.:|.|:::|..||::|||:..|:.:||||::|:.:.:.|.|::.
Mosquito   901 GGKDGNKPVAAAAASAVAAFDRKLEIEILPPAPALHVSFSRAPSEVLAGEVIPLKMNMTNAGVSV 965

  Fly   931 IEEIYLGCDNPRCVSLLDQHSQMPLAMMSSLRNLSNDKLVKDKEIRGQRVYRLLNRPGLAALDAQ 995
            :.:||:..||||.|.|....:.:||::...|:||:|:.:.:|:|.|.|.|.|.........:...
Mosquito   966 LNDIYVCIDNPRYVLLNPSEADIPLSIRRDLQNLANENVGRDREARKQYVCRAFREADGNFIAPN 1030

  Fly   996 QVQTISLWVQAPHQAGPFTLRLLFYYSLPTVANSP-IKYRLVRHIWQLQVESCLQADSTCVVSNA 1059
            :.:|.:||:|||:..|...::|:.||::|  .:.| :|:|||||.|...|...|..|:.|.:||.
Mosquito  1031 ETKTATLWLQAPYSKGQKDIKLMIYYAMP--QDYPKLKHRLVRHTWNFNVNDSLLVDANCNLSNP 1093

  Fly  1060 VTNELGLDVNVRNQHAVEG---TEVYINSISLYSTEFKLNPDRLHIMNSMGVSPGQAGAQCLKSS 1121
            ...|||:||||:|.:.|..   ||:.||.:.||.:.::|..:|:..:.:.|.:..|:|.. ||::
Mosquito  1094 TKRELGVDVNVKNLNQVHHPLMTEIVINELYLYCSAYELQQNRVVYIKTPGHTKLQSGGG-LKTN 1157

  Fly  1122 ICCNFQCRLLEKETQEEYKDIPSIKTLLHSRLSHLKILPAQHAQQVEQHMPPIHDPHSFLTNEET 1186
            ...:.:|.|..:.....|..  :.:..:..:||.:.:..::.|.:..  :|.:....|||...||
Mosquito  1158 ETVSLRCNLQRRTADVAYDG--NFQGYVSQKLSTVTVRASEPAAKAT--LPALEAAGSFLLKNET 1218

  Fly  1187 VYFNTNI--STEEFNASVADYVPHATLVLSWSALVAREEGQRLACGLHFIKLYKLFETGHCPAAP 1249
            .:.....  |.||||..|.....|.||.::|||.:......|.|.|.||::|..|::|.:||  |
Mosquito  1219 KFIRVYEPGSNEEFNQIVNQRDSHMTLCVNWSATINDNGASRKAYGQHFVQLRNLYDTVYCP--P 1281

  Fly  1250 TASFLRRRHSSDDTLDNRREFPLPEGALNNEDAWQPLADADEEDYWEPNENYVGQRCLLED 1310
            :....:...:....:         .|..::.|...|:.:.|.:..|..|::||.|||.||:
Mosquito  1282 SERLQQITFTGQSNV---------YGIFDDLDKVMPVENDDIDSGWGVNQSYVAQRCFLEE 1333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(3)76BDm	NP_649135.2	TRAPPC-Trs85	160..608	CDD:463688	284/466 (61%)
l(3)76BDm	XP_308792.5	None