Protein Alignment Lon and lon1

DIOPT Version :9

• Sequence 1: NP_730435.2
• Gene: Lon / 40138
• FlyBaseID: FBgn0036892
• Length: 1024
• Species: Drosophila melanogaster
• Sequence 2: NP_593035.1
• Gene: lon1 / 2541875
• PomBaseID: SPAC22F3.06c
• Length: 1067
• Species: Schizosaccharomyces pombe
• Alignment Length: 1038
• Identity: 445/1038 - (42%)
• Similarity: 628/1038 - (60%)
• Gaps: 131/1038 - (12%)

  Fly    24 NRPIQSSLMQYCRDRSLRLQRLHGANLMVQRFYS--RKRDDSNGDIIMGPDLMSDQ-------DT 79
            |..:.|:..:..:|.....|.|..::...:..||  :.....|.:..:|.:...|:       :.
pombe    83 NESLPSTDKKKKKDNDDFKQNLKSSSNKTEEKYSATQASKSKNDEFELGGEENEDEMPLNGEFNK 147

  Fly    80 HLPATVAVPDVWPHVPLLAMRKNPLFPRFMKIVEVSNPIIMDLLRRKVKLNQPYVGVFLKKTDG- 143
            ::||..:||||:|.:..|.:.:.||||.|.|.:...||.:.:.::..:|..|||:|.||.|.:.
pombe   148 NVPAKYSVPDVYPQLLALPIARRPLFPGFYKAIVTKNPSVSEAIKELIKKRQPYIGAFLLKDENT 212

  Fly   144 EEELITNLNDVYNLGTFAQIQEL--QDLGDK--LRMVVVAHRRIRITGQVVEDVPPPKPVKMTTL 204
            :.::|||::.||.:|.||||..:  ...|.:  |..|:..|||||||     ::.|||
pombe   213 DTDVITNIDQVYPVGVFAQITSIFPAKSGSEPALTAVLYPHRRIRIT-----ELIPPK------- 265

  Fly   205 HYPLFNIKLQIPAED-QSTDQADAAPIKSRSDPARKPRGRIPRSRTGKSRESAAAEELIQNQTLE 268
                         || .|...:|||.::                 |.||      ..|..|..::
pombe   266 -------------EDADSAASSDAAELE-----------------TDKS------SNLSSNGEVK 294

  Fly   269 PPLK--SGKVESSSLPKPPTEEKIVEPETGAKENVNQSAPSAQPVLIVEVENV-KQPIYKQTEEV 330
            ..||  :||.|         .||.||......:|..        |.:|.|||| .:|..:|...:
pombe   295 SDLKQDNGKEE---------PEKEVESTPSILQNFK--------VSLVNVENVPNEPFKRQDPVI 342

  Fly   331 KALTQEIIKTLRDIITMNPLYRESLQ--QMLHQNQRVVDNPIYLCDLGASLSAGEPAELQKILEE 393
            ||:|.||:...:||..::||:||.:.  .:...:..|.|.|..|.|..|::||.:..|||::||.
pombe   343 KAVTSEIMNVFKDIANVSPLFREQIANFSISQTSGNVFDEPAKLADFAAAVSAADHRELQEVLEA 407

  Fly   394 TDIPERLQLALTLLKKELELSRLQQKIGREVEEKVKQQHRKYILQEQLKVIKKELGIEKDDKDAI 458
            |:|.:|||.||.:|||||..::||.||.:|:|:|:.|:|::|:|.||||.||:|||.|.|.|:|:
pombe   408 TNIGDRLQKALYVLKKELLNAQLQHKINKEIEQKITQRHKEYLLTEQLKQIKRELGQELDSKEAL 472

  Fly   459 GEKYREKLKDKVVPEAIMTVIDEELTKLNFLESHSSEFNVTRNYLDWLTSLPWGVISTENLCLEK 523
            ..:::::.:...:|:.:..|.::||:|...||..::|||:|||||||:|.||||..|.||..|:.
pombe   473 VTEFKKRTESLSMPDHVKKVFNDELSKFQHLEPMAAEFNITRNYLDWITQLPWGKRSVENFDLDH 537

  Fly   524 ATETLNDDHYGMEDIKKRILEFIAVSSLKGSTQGKILCFHGPPGVGKTSIAKSIARALNREYFRF 588
            |.|.|:.||||::|:|.|:||.:||..|:|:.||||:|..|||||||||:.||||.|||||:|||
pombe   538 AKEVLDRDHYGLKDVKDRVLELVAVGKLRGTMQGKIMCLVGPPGVGKTSVGKSIASALNREFFRF 602

  Fly   589 SVGGMTDVAEIKGHRRTYVGAMPGKLIQCLKKTKIENPLVLIDEVDKIGKGYQGDPSSALLELLD 653
            ||||:|||||||||||||:||||||::|.|||.:.||||:||||:||:||.:||||:||||||||
pombe   603 SVGGLTDVAEIKGHRRTYIGAMPGKIVQALKKVQTENPLILIDEIDKVGKSHQGDPASALLELLD 667

  Fly   654 PEQNANFLDHYLDVPVDLSRVLFICTANVIDTIPEPLRDRMELIEMSGYVAEEKIAIARQYLMPQ 718
            .|||:.|||:|:|:|:|:|.|||:||||.|||||.||.||||:||:||||:.||:.||:.||:||
pombe   668 SEQNSAFLDYYMDIPLDVSSVLFVCTANTIDTIPPPLLDRMEVIELSGYVSAEKVNIAKGYLIPQ 732

  Fly   719 AMKDCGLTDKHINISEDALNMLIRSYCRESGVRNLQKHIEKVIRKVAFRVVK------------- 770
            |...|||.|.::|||:||:..||..|..|||||||:|.|||:.||.:|.:||
pombe   733 AKAACGLKDANVNISDDAIKGLISYYAHESGVRNLKKSIEKIFRKTSFSIVKEIDDELNSKEKST 797

  Fly   771 -----------------KEGEHFP------VNAD----NLTTFLGKQIFSSDRMYATTPVGVVMG 808
                             ||....|      ||.:    :||.:||..|::|.|:|.|||.|||||
pombe   798 GKSGKKTSPQSSEDAANKEASSVPLKVPDKVNIEIEEKDLTKYLGPPIYTSQRLYDTTPPGVVMG 862

  Fly   809 LAWTAMGGSSLYIETSRRHIRQGAKTDPNTVAGSLHITGNLGDVMKESAQIALTVARNFLYSLEP 873
            |.||.|||.|:|:||..::|.....|.      ||..||.||||||||::|:.:.:::||....|
pombe   863 LGWTPMGGVSMYVETIVKNILSSNSTP------SLERTGQLGDVMKESSEISYSFSKSFLSKHFP 921

  Fly   874 NNLFLEQEHIHLHVPEGATPKDGPSAGITIITALVSLATGKPVRQDIAMTGEVSLKGKVLPVGGI 938
            ||.|.|...:|:|.|||:..|||||||||:.|:|:|||...||....|||||::|.||:|.:||:
pombe   922 NNKFFEHARLHMHCPEGSISKDGPSAGITMATSLLSLALDTPVPATTAMTGELTLTGKILRIGGL 986

  Fly   939 KEKTIAARRSGVNCLILPVDNKKDFEELPTYITDGLEVHFATTYEDVYKIAFTDVTETTTNNV 1001
            :|||:||:.||:..::.|..|..|:|:||.|:.:||.......|:||:|..|:::.....||:
pombe   987 REKTVAAKLSGMKEILFPKSNLADWEQLPDYVKEGLTGVPVAWYDDVFKRVFSNIDAEKCNNL 1049

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lon	NP_730435.2	LON	93..>148	CDD:197740	17/55 (31%)
		lon	95..990	CDD:273258	425/945 (45%)
		P-loop_NTPase	530..>581	CDD:304359	31/50 (62%)
		AAA	560..702	CDD:278434	105/141 (74%)
		ChlI	778..991	CDD:304493	102/216 (47%)
lon1	NP_593035.1	LON	161..>217	CDD:197740	17/55 (31%)
		lon	163..1038	CDD:273258	425/945 (45%)
		AAA	574..716	CDD:278434	105/141 (74%)
		ChlI	832..1035	CDD:304493	99/208 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	225	1.000	Domainoid score	I531
eggNOG	1	0.900	-	-		E1_COG0466
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3521
Inparanoid	1	1.050	777	1.000	Inparanoid score	I77
OMA	1	1.010	-	-		QHG55281
OrthoFinder	1	1.000	-	-		FOG0002884
OrthoInspector	1	1.000	-	-		oto102128
orthoMCL	1	0.900	-	-		OOG6_100411
Panther	1	1.100	-	-	LDO	PTHR43718
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R662
SonicParanoid	1	1.000	-	-		X2242
TreeFam	1	0.960	-	-
	14	13.860