|
Fly 2 SCSQNETAAAKVLETQRAQE-------------SGSENEETDSIT-------------DQSSQSK 40
||.:| .|.|..||..... |..:|:...|:. |:..:|.
Human 572 SCGKN--TAKKEFETSNGDSLLGLPEGALISKCSREKNKPQRSLVCGSKVKLCYIGAGDEEKRSD 634
Fly 41 SIKSATQFSVQRSDTDGLRMRISAIRPTLGVVATKKPPKSRKMSTQDTESGCSEAKNR------- 98
||...|......||.|.:.....:....|.: |. :...||:..|..||.
Human 635 SISICTTSDDGSSDLDPIEHSSESDNSVLEI------PD----AFDRTENMLSMQKNEKIKYSRF 689
Fly 99 -AVSKKVKVKRKKLASSS------GISKSDKVSKSKKSQISAFSSDSEDDLPLK--VHQQR---- 150
|.:.:||.|:|.|.|:| |.:||.:.. ::.||::. .||... ||:.:
Human 690 AATNTRVKAKQKPLISNSHTDHLMGCTKSAEPG-TETSQVNL------SDLKASTLVHKPQSDFT 747
Fly 151 ----APRVLLSAIIQA--------------AQSASKPTLDIGISSSDNELPNLV-------QAAI 190
:|:..||:.|.: ..|.||......|.....|.|.:. :.::
Human 748 NDALSPKFNLSSSISSENSLIKGGAANQALLHSKSKQPKFRSIKCKHKENPVMAEPPVINEECSL 812
Fly 191 KRVESDTEDTTVEGSFRKAAKDKNLPQYQSTLLQDFMEKTQMLGQTVNAKLAEEKVAKAKEETLV 255
|...|||:.:.: .|..|:.|...| .||.:..||| ::.:.:
Human 813 KCCSSDTKGSPL-ASISKSGKVDGL-----KLLNNMHEKT-------------------RDSSDI 852
Fly 256 QTAVPRKRRGRPKKVVPTVPAPGNSGPAINES-ADSGVISTTSTTQSTTPSPKMQNENAVPTGSL 319
:|||.:......|:: |..::.|. :||| ::.||..:...:|.....:
Human 853 ETAVVKHVLSELKEL---------SYRSLGEDVSDSG---------TSKPSKPLLFSSASSQNHI 899
Fly 320 PIASSSKPKIDMAYL----------DKRMYATERVLYPPPRSKRRQNNKKTACS-------SSNK 367
||....|....:..| .:.|.|...|.|..|.......|.....| |::.
Human 900 PIEPDYKFSTLLMMLKDMHDSKTKEQRLMTAQNLVSYRSPGRGDCSTNSPVGVSKVLVSGGSTHN 964
Fly 368 EELQLDPLWREIDVNKKFRLRSMSVGAASGTGASTTICSKVLAAKSGYVSDYGSVRHQRSSHNHN 432
.|.:.| .:.:....|.:|..:.:..::.|:..|.:||
Human 965 SEKKGD--------------GTQNSANPSPSGGDSALSGELSASLPGLLSD-------------- 1001
Fly 433 SGYKSD--ASCKSRYSTKSCMSRRSRAKSCGYRSDCKESGK----------------SGLRMRRK 479
|.| ||.||| ..|::|| :|| || |.|.| ..|:..||
Human 1002 ---KRDLPASGKSR---SDCVTRR----NCG-RS--KPSSKLRDAFSAQMVKNTVNRKALKTERK 1053
Fly 480 RRASML------------------LKSSADDTVEDQDILQLAGLSLGQSSEESNEYISKPSLKSL 526
|:.:.| |:..|:|. ..:|.||: :|..:.|..::.|.....|.
Human 1054 RKLNQLPSVTLDAVLQGDRERGGSLRGGAEDP-SKEDPLQI----MGHLTSEDGDHFSDVHFDSK 1113
Fly 527 PTTSASKKYGEINRYVTTGQYF--GRGGSL-SATNPDN--------FISK----MMNQRKETP-- 574
...|...|..| .|..| |:|..| |..|.:| .:.| .:|||:..|
Human 1114 VKQSDPGKISE------KGLSFENGKGPELDSVMNSENDELNGVNQVVPKKRWQRLNQRRTKPRK 1172
Fly 575 ------APSKSSCKIK----------------SRRSSAAS-----------------------MC 594
....|.|..: ..|:.:|| :|
Human 1173 RMNRFKEKENSECAFRVLLPSDPVQEGRDEFPEHRTPSASILEEPLTEQNHADCLDSAGPRLNVC 1237
Fly 595 SSYVSGVSRMRRRHRRKSF------------SHNKSLNIDSKLLTE-----------------IE 630
....:.:..|.:.....|. |..|.|...||.|.| ::
Human 1238 DKSSASIGDMEKEPGIPSLTPQAELPEPAVRSEKKRLRKPSKWLLEYTEEYDQIFAPKKKQKKVQ 1302
Fly 631 IITSTFNSRCRIQDDRLTGSSGKEKLLADANKLQATLAAP-----------SPAQQLTLNGGG-- 682
......:|||..:.....|.|..:....|.|.|.:|...| .|..|..|.||.
Human 1303 EQVHKVSSRCEEESLLARGRSSAQNKQVDENSLISTKEEPPVLEREAPFLEGPLAQSELGGGHAE 1367
Fly 683 -PASTLSKPLKRGLKKRKLSEPLVDFAMLSASASGTPNGSGSSNGNTKRRHKKS----QSND--- 739
|..|||.|:...:..| |.::...|.....| |..:||:.|.: :|||
Human 1368 LPQLTLSVPVAPEVSPR----PALESEELLVKTPG--------NYESKRQRKPTKKLLESNDLDP 1420
Fly 740 SSSPDDHKLPLKKRHYLLTPGERPPAEVAFANGKLNAEAWAAAAAAAKSTASTKSQAQFNARSVK 804
...|....|.|.|:.| ||........:|.|::.|: .|...:.|
Human 1421 GFMPKKGDLGLSKKCY---------------------EAGHLENGITESCATSYSK-DFGGGTTK 1463
Fly 805 SALTPKKR-------------HLLEQPTSVSGAGSSASNSPLRIVVD-NNSISGGKLLDISPSSL 855
....|:|| .:....:|....||.....|.|.... ..::..| ::..|...
Human 1464 IFDKPRKRKRQRHAAAKMQCKKVKNDDSSKEIPGSEGELMPHRTATSPKETVEEG--VEHDPGMP 1526
Fly 856 CSLKQQ-RRGGAAKQKVSAAKDLVQLQSPAGSYPPPGVFEPSVELEIQIPLSKLNESVITKAEVE 919
.|.|.| .|||.|..|.:..:: ..||.|.::.:|:..
Human 1527 ASKKMQGERGGGAALKENVCQN----------------------------CEKLGELLLCEAQCC 1563
Fly 920 SPL-LSALDIKEDTKKEVGQRVVETLLHKTGGNLLLKRKRKKINRTGFPTVRRKKRKVSVEQQTT 983
... |..|.:.|..:.:.......|.:|.. .:.|:..:.:.|...|...:...:..|::...
Human 1564 GAFHLECLGLTEMPRGKFICNECRTGIHTC---FVCKQSGEDVKRCLLPLCGKFYHEECVQKYPP 1625
Fly 984 AVIDEHEPEFDPDDEPLQSLR-------ETRSSNNVNVQAAPNPPLDCERVPQAGEARETFVART 1041
.|:.. :..| ...::|..||.|:....:.|.|.|.|..|.:..:|..
Human 1626 TVMQN------------KGFRCSLHICITCHAANPANVSASKGRLMRCVRCPVAYHANDFCLAAG 1678
Fly 1042 NQKAPRLSVVALERLQRPQTPARGRPRGRKPKNREQAEAA--------------PQPPPKSEPEI 1092
::.....|::..... ||.|| .:|.|....: ...|.....|.
Human 1679 SKILASNSIICPNHF----TPRRG------CRNHEHVNVSWCFVCSEGGSLLCCDSCPAAFHREC 1733
Fly 1093 RPAKKRGRQPKQPVLEEPPPTPPPQQKKNKMEPNIRLPDGIDPNTNFSCKIRLKRRKNLEAGTQP 1157
. ||.:|:| |:.| .:.:||.:|
Human 1734 L--------------------------------NIDIPEG-----NWYC-------NDCKAGKKP 1754
Fly 1158 KKEKPVQPVTVEEI---PPEIPVSQEEIDAEAEAKRLDSIPTEHDPLPASESHNP----GPQDYA 1215
...:.|. |.|... |.||...: ::|:..|.:.......| |..||.
Human 1755 HYREIVW-VKVGRYRWWPAEICHPR-------------AVPSNIDKMRHDVGEFPVLFFGSNDYL 1805
Fly 1216 SCSE-----------SSEDKASTTSLRKLSKVKKTYLVAGLFSNHYKQSLMPPPAKVNKKPGLEE 1269
...: ||:|| :..|: ...||::|....|:..: |:.
Human 1806 WTHQARVFPYMEGDVSSKDK----------------MGKGV-DGTYKKALQEAAARFEE---LKA 1850
Fly 1270 QVGPASLLPPPPYCEKYLRRTEMDFELPYDIWWAYTNSKLPTRNVVPSWNYRKI-----RTNVYA 1329
| |.||:.:.|.: |.|.| |.:.:.|: |..::.
Human 1851 Q--------------KELRQLQEDRK----------NDKKP-----PPYKHIKVNRPIGRVQIFT 1886
Fly 1330 ESVRPNLAGFDHPTCNCKNQGEKSC-LDN-CLNRMVYTECSPSNCPAGEKCRNQKIQRHAVAPGV 1392
..:. :.|.||||...|..| :|: |:|||:..||.|:.||||.:|:||...:... |.|
Human 1887 ADLS------EIPRCNCKATDENPCGIDSECINRMLLYECHPTVCPAGGRCQNQCFSKRQY-PEV 1944
Fly 1393 ERFMTADKGWGVRTKLPIAKGTYILEYVGEVVTEKEFKQRMASIYLND-THHYCLHLDGGLVIDG 1456
|.|.|..:|||:|||..|.||.::.|||||::.|:|.:.|:.....:| |:.|.|.||...:||.
Human 1945 EIFRTLQRGWGLRTKTDIKKGEFVNEYVGELIDEEECRARIRYAQEHDITNFYMLTLDKDRIIDA 2009
Fly 1457 QRMGSDCRFVNHSCEPNCEMQKWSVNGLSRMVLFAKRAIEEGEELTYDYNFSLFNPSEGQPCRCN 1521
...|:..||:||.|:||||.|||||||.:|:.|||...|:.|.|||::||.......: ..|:|.
Human 2010 GPKGNYARFMNHCCQPNCETQKWSVNGDTRVGLFALSDIKAGTELTFNYNLECLGNGK-TVCKCG 2073
Fly 1522 TPQCRGVIGGKSQRVKPLPAVEAKPSGEGLSGRNGRQRKQKAKKHAQRQAGKDISSAVAVAKLQP 1586
.|.|.|.:| .:|..:.:: .::|:||..::|.|| .:.|.
Human 2074 APNCSGFLG-------------VRPKNQPIA------TEEKSKKFKKKQQGK--------RRTQG 2111
Fly 1587 LSEKEKKLVRQFNTFLVRNFEKIRRCKAKRA-----SDAAATASSPALGTTNG---------DIP 1637
...|| |:...|...:..::..||.... :|.......|| | ||.
Human 2112 EITKE----REDECFSCGDAGQLVSCKKPGCPKVYHADCLNLTKRPA-----GKWECPWHQCDIC 2167
Fly 1638 GRRPST-----PSS------------PSLAAQISAL----CSPRNIKTRGLTQAVHDP-ELEKMA 1680
|:..:: ||| ..|..::|.. |.|..::...:.:.|..| .|....
Human 2168 GKEAASFCEMCPSSFCKQHREGMLFISKLDGRLSCTEHDPCGPNPLEPGEIREYVPPPVPLPPGP 2232
Fly 1681 KMAVVLRDICSAMETLKMSDLLTTVSSKKKKPIKT----TLSGK-LGSTAATSKVEFRSIQAQVE 1740
...:..:....|.:..|||| |.|..| :||.| |..|.....:..|
Human 2233 STHLAEQSTGMAAQAPKMSD---------KPPADTNQMLSLSKKALAGTCQRPLLPER------- 2281
Fly 1741 QGHYKTPQEFDDHMQQLFVEAKQQHGDDEGKEKALQSLKDSYEQQKIASYVQLVEILGDSESLQS 1805
|.|..|...|...:.:...|.....:..:.|.:.......:| |....| |
Human 2282 ------PLERTDSRPQPLDKVRDLAGSGTKSQSLVSSQRPLDRPPAVA---------GPRPQL-S 2330
Fly 1806 FKPKEVLSSEEEPGKIA-------------VKKSPGAK-------ERDSPIVPLKVTPPPLLPIE 1850
.||..|.|....|...: :.||.||. |:.|....|::.||..|.|.
Human 2331 DKPSPVTSPSSSPSVRSQPLERPLGTADPRLDKSIGAASPRPQSLEKTSVPTGLRLPPPDRLLIT 2395
Fly 1851 ASP 1853
:||
Human 2396 SSP 2398
| 
