Protein Alignment ash1 and set-13

DIOPT Version :10

• Sequence 1: NP_524160.2
• Gene: ash1 / 40133
• FlyBaseID: FBgn0005386
• Length: 2226
• Species: Drosophila melanogaster
• Sequence 2: NP_494371.1
• Gene: set-13 / 173626
• WormBaseID: WBGene00019690
• Length: 402
• Species: Caenorhabditis elegans
• Alignment Length: 496
• Identity: 104/496 - (20%)
• Similarity: 169/496 - (34%)
• Gaps: 157/496 - (31%)

  Fly  1128 RLPDGIDPNTN-----FSCKIRLKRRKN------LEAGTQPKKEKPVQPVTVEEIPPEIPVSQEE 1181
            ||....|.|.:     ||.|:..:..::      :...||||.|:          .|.|||::..
 Worm    12 RLTTFTDSNISPTSLIFSSKMSSRTLRSSSSSNAISTKTQPKTEE----------APLIPVTKGP 66

  Fly  1182 IDAEAEAKRLDSIPTEHDPLPASESHNPGPQDYASCSESSEDKASTTSLRKLSKVKKTYLVAGLF 1246
            : ....:...|....:|...|::....   ..:.:......:|::..::|:..|::
 Worm    67 V-IRMTSNMADKAQNDHSMWPSTSKFE---SIWGNVLGERVNKSTIAAIREGMKIE--------- 118

  Fly  1247 SNHYKQSLMPPPAKVNK-----KPGLEEQVGPASLLPPPPYCEKYLRRTEMDFELPYDIWWAYTN 1306
                           ||     :||.:....||        |..:...:.:......||   .|.
 Worm   119 ---------------NKVTCGCRPGQDCSTNPA--------CRCFQTASRLREHFGSDI---LTR 157

  Fly  1307 SKLPTRNV-VPSWNYRKIRTNVYAESVRPNLA--GFDHPTCNCKNQGEKSCLDNCLNRMVYTECS 1368
            .| |.:.| ...|:             ||..|  |    :|.||.|    |..|.|..:    |.
 Worm   158 GK-PVKTVDTMYWD-------------RPMFACSG----SCGCKGQ----CNLNALQDI----CE 196

  Fly  1369 PSNCPAGEKCRNQKIQRHAVAPGVERFMTADKGWGVRTKLPIAKGTYILEYVGEVV------TEK 1427
                   :..:..||.|           |..||:.|.:...|.||:.:||:.||:.      :..
 Worm   197 -------DPAKKFKITR-----------TDGKGFCVYSARVIKKGSPVLEFSGEITDYLAIKSNA 243

  Fly  1428 EFKQRMASIYLNDTHHYC--LHLDGGLV----------------IDGQRMGSDCRFVNHSCEPNC 1474
            :.:|....:|.|:| ..|  ...:..|.                |:....|:..||.:|.|:.|.
 Worm   244 DIEQYSIMLYNNET-KLCDFFSKEENLSSKYKKILWSAYRSKAWINPLNRGNCARFFSHGCKANM 307

  Fly  1475 EMQKWSVNGLS----RMVLFAKRAIEEGEELTYDYNFSLFNPSEGQPCRCNTPQCRGVIGGKSQR 1535
            |:.:....|.|    ::|||||..|:.|.|||::|..|......|..|.|..  |      |.:.
 Worm   308 ELGRVFQGGFSPADMKIVLFAKEIIKPGTELTFNYGPSYKEIFLGNKCLCEA--C------KKEA 364

  Fly  1536 VKPLPAVEAKPSGEGLSGRNGRQRKQ--KAKKHAQRQAGKD 1574
            ||.|.....:..      :|.|...:  ..||..::..||:
 Worm   365 VKKLENAVKRIL------KNSRDPSEPPSKKKSVKKLDGKE 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ash1	NP_524160.2	PHA03247	<1018..1281	CDD:223021	28/168 (17%)
		AWS	1340..1388	CDD:197795	11/47 (23%)
		SET_ASH1L	1391..1531	CDD:380951	43/167 (26%)
		Bromo_ASH1	1680..1787	CDD:99955
		PHD_ASH1L	1858..1900	CDD:277023
		BAH_polybromo	1929..2073	CDD:240068
set-13	NP_494371.1	SET	200..348	CDD:214614	42/159 (26%)