Protein Alignment Shal and Kcnc4

DIOPT Version :10

• Sequence 1: NP_001097646.1
• Gene: Shal / 40129
• FlyBaseID: FBgn0005564
• Length: 571
• Species: Drosophila melanogaster
• Sequence 2: XP_038959057.1
• Gene: Kcnc4 / 684516
• RGDID: 1589169
• Length: 663
• Species: Rattus norvegicus
• Alignment Length: 476
• Identity: 169/476 - (35%)
• Similarity: 249/476 - (52%)
• Gaps: 96/476 - (20%)

  Fly    41 EKLLINVSGRRFETWRNTLEKYPDTLLGSNEREFFYDED-----------------------CKE 82
            ||::|||.|.|.||:|:||...|.|.|.     :..|.|                       | |
  Rat    36 EKIIINVGGTRHETYRSTLRTLPGTRLA-----WLADPDGGGRPESDGGGAGSSGSSGGGGGC-E 94

  Fly    83 YFFDRDPDIFRHILNYYRTGKLHYPKHECLTSYDEELAFFGIMPDVIGDCCYEDYRDRKRENAER 147
            :||||.|.:|.::||||||||||.|...|...::|||.|:||....:..||:..||..:  :||.
  Rat    95 FFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELTFWGIDETDVEPCCWMTYRQHR--DAEE 157

  Fly   148 LMDDKLS------------ENGDQN----LQQL----------------TNMRQKMWRAFENPHT 180
            .:|...|            |.||..    ||:|                ...:.:||..||:|::
  Rat   158 ALDIFESPDGGGGGAGPGDEAGDDERELALQRLGPHEGGSGPGAGSGGCRGWQPRMWALFEDPYS 222

  Fly   181 STSALVFYYVTGFFIAVSVMANVVET---------VPCGHRPGRAGTLPCGERYK------IVFF 230
            |.:|.|..:.:.|||.||:....:||         |...||.|...::    |::      .:..
  Rat   223 SRAARVVAFASLFFILVSITTFCLETHEAFNIDRNVTEIHRVGNITSV----RFRREVETEPILT 283

  Fly   231 CLDTACVMIFTAEYLLRLFAAPDRCKFVRSVMSIIDVVAIMPYYIGLGITDND-----DVSGAFV 290
            .::..|||.||.|:|:|:...||...||:::::|||.|||:|:|:.:|::...     ||.|...
  Rat   284 YIEGVCVMWFTLEFLVRIVCCPDTLDFVKNLLNIIDFVAILPFYLEVGLSGLSSKAARDVLGFLR 348

  Fly   291 TLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLVFSLAMAIIIFATVMFYAE--------- 346
            .:|..|:.||||.:||..|||:||:||::..:|...|:..||:.::||||:::|||
  Rat   349 VVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGARPSDP 413

  Fly   347 KNVNGTNFTSIPAAFWYTIVTMTTLGYGDMVPETIAGKIVGGVCSLSGVLVIALPVPVIVSNFSR 411
            :..:.|:|.:||..||:.:|||||||||||.|:|.:|.:||.:|:|:|||.||:||||||:||..
  Rat   414 RGNDHTDFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGM 478

  Fly   412 IYHQNQRADKRKAQRKARLAR 432
            .|.......|...:||..:.|
  Rat   479 YYSLAMAKQKLPKKRKKHVPR 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shal	NP_001097646.1	BTB_POZ_Shal-like	6..144	CDD:349727	47/125 (38%)
		Ion_trans	188..415	CDD:459842	100/255 (39%)
		DUF3399	471..535	CDD:463381
Kcnc4	XP_038959057.1	Potassium_chann	1..29	CDD:431870
		BTB_KCNC2_4	35..159	CDD:349722	49/130 (38%)
		Ion_trans	226..484	CDD:459842	102/261 (39%)