Protein Alignment Shal and kcnq1.1

DIOPT Version :10

• Sequence 1: NP_001097646.1
• Gene: Shal / 40129
• FlyBaseID: FBgn0005564
• Length: 571
• Species: Drosophila melanogaster
• Sequence 2: XP_073762763.1
• Gene: kcnq1.1 / 557498
• ZFINID: ZDB-GENE-061214-5
• Length: 669
• Species: Danio rerio
• Alignment Length: 274
• Identity: 74/274 - (27%)
• Similarity: 121/274 - (44%)
• Gaps: 60/274 - (21%)

  Fly   172 WRAFENPHTSTSALVFYYVTGFFIAVS-VMANVVETVPCGHRPGRAGTLPCGERYKIV----FFC 231
            |:.|           .|:.|.|.|.:| ::.:|:.|:               :.|:.:    .|.
Zfish   102 WKCF-----------VYHFTVFLIVLSCLILSVLSTI---------------DEYQALANKTLFW 140

  Fly   232 LDTACVMIFTAEYLLRLFAAPDRCKFV---------RSVMSIIDVVAIMPYYIGLGITDNDDV-- 285
            ::...||.|..||::||::|..|.|:|         |..:|:||::.::...|.|....|..|
Zfish   141 MELVLVMFFGVEYVVRLWSAGCRSKYVGILGRLRFARKPISVIDLIVVVASIIVLAFGSNGQVFA 205

  Fly   286 SGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASEL------GFLVFSLAMAIIIFATVMFY 344
            :.|...:|..::.|:....|.....|:||..:.....||      |||.       :||::...|
Zfish   206 TSAVRGVRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLG-------LIFSSYFVY 263

  Fly   345 -AEKNV----NGTNFTSIPAAFWYTIVTMTTLGYGDMVPETIAGKIVGGVCSLSGVLVIALPVPV 404
             |||:.    ..:.|.|...|.|:.:||:||:||||.||:|..||.:....|:..:...|||..:
Zfish   264 LAEKDAVDDHGNSGFGSYADALWWGVVTVTTIGYGDKVPQTWIGKTIASCFSVFAISFFALPAGI 328

  Fly   405 IVSNFSRIYHQNQR 418
            :.|.|:....|.||
Zfish   329 LGSGFALKVQQKQR 342

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shal	NP_001097646.1	BTB_POZ_Shal-like	6..144	CDD:349727
		Ion_trans	188..415	CDD:459842	69/253 (27%)
		DUF3399	471..535	CDD:463381
kcnq1.1	XP_073762763.1	None