| Sequence 1: | NP_001097646.1 | Gene: | Shal / 40129 | FlyBaseID: | FBgn0005564 | Length: | 571 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_742039.1 | Gene: | Kcnk2 / 170899 | RGDID: | 621448 | Length: | 426 | Species: | Rattus norvegicus |
| Alignment Length: | 197 | Identity: | 41/197 - (20%) |
|---|---|---|---|
| Similarity: | 68/197 - (34%) | Gaps: | 81/197 - (41%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 309 GLRILGYTLKSCASELG-------------FLVFSLA---------MAIIIFATVMFYA-----E 346
Fly 347 KNVNGTNFTSIPAAFWYTIVTMTTLGYGDMVPETIAGK----------------IVGGVCSLSGV 395
Fly 396 L--------VIALPVPVIVSNFS-----------------------RIYHQNQRADKRKAQRKAR 429
Fly 430 LA 431 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Shal | NP_001097646.1 | BTB_POZ_Shal-like | 6..144 | CDD:349727 | |
| Ion_trans | 188..415 | CDD:459842 | 34/179 (19%) | ||
| DUF3399 | 471..535 | CDD:463381 | |||
| Kcnk2 | NP_742039.1 | Important for GNG4 binding and L-glutamate release in astrocytes. /evidence=ECO:0000269|PubMed:23021213 | 17..38 | ||
| Important for GNG4 binding and L-glutamate release in astrocytes. /evidence=ECO:0000269|PubMed:23021213 | 51..61 | ||||
| Ion_trans_2 | <138..196 | CDD:462301 | 3/14 (21%) | ||
| Selectivity filter 1. /evidence=ECO:0000305|PubMed:26919430 | 157..162 | ||||
| Ion_trans_2 | 234..312 | CDD:462301 | 20/84 (24%) | ||
| Selectivity filter 2. /evidence=ECO:0000305|PubMed:26919430 | 266..271 | 2/4 (50%) | |||
| Interaction with AKAP5. /evidence=ECO:0000250|UniProtKB:P97438 | 313..326 | 3/12 (25%) | |||
| Essential for chloroform and halothane sensitivity. /evidence=ECO:0000250|UniProtKB:P97438 | 337..385 | 9/34 (26%) | |||
| Blue background indicates that the domain is not in the aligned region. | |||||