Protein Alignment: Ltn1 and ltn1

• Sequence 1: NP_730427.1
• Gene: Ltn1
• FlyBaseID: FBgn0262517
• Length: 1747
• Species: Drosophila melanogaster
• Sequence 2: XP_012812767.1
• Gene: ltn1
• XenbaseID: XB-GENE-1217544
• Length: 1779
• Species: Xenopus tropicalis
• Alignment Length: 1915
• Identity: 503/1916 (26%)
• Similarity: 856/1916 (45%)
• Gaps: 305/1916 (16%)

  Fly     1 MGGKTKQAPRTKNNAKPSSSSRTAELLGSST---PIFVGF-SAQTDGGGLVPFAPGFASAEQMPD 61
            ||||.||  |||.||:||||.|.||||...:   |.|:|| |:|:|..    :.|....||::
 Frog     1 MGGKNKQ--RTKGNARPSSSGRAAELLAKESGTIPGFIGFGSSQSDHS----YVPAVQGAEEV-- 57

  Fly    62 SFDAAISPQTQIILRKLSKKDPMTKKKALQELHELIEQSDVEVLKNILPLWPKYYLNLASDPEHT 126
              |:.:....:::||||||:|.:||.||:||...:.::.::|.::.:||.||:.|..::.|.:..
 Frog    58 --DSLVDADFRLVLRKLSKRDAITKLKAMQEFGFMCKEREMETVRGVLPYWPRIYCKISLDLDRR 120

  Fly   127 VREQTQTVLQLLMAKCKKAMAPYLKLLVPVWLGSRFDTYAPAASIASQSFRDTFAGNANRSREVC 191
            |||.||...:.|:.|.||.:||:||.|:..||.::.|||:||||.|..:|...|.  |::..|..
 Frog   121 VREATQQAFEQLILKVKKYLAPHLKSLMGFWLIAQCDTYSPAASSARVAFEAAFP--AHKQPEAL 183

  Fly   192 MHCQVEILEYATRNLTFHTAATLSIGKSLTPEDAEQKYQRVIISSLKLLSFFMGQTAQTEELSQV 256
            ..|:.||:.....:|...|..|||..:::..||.|.||.||:..||..|...:....::|. |.:
 Frog   184 AFCKEEIMNVLLDHLLKETPDTLSDTQAVPIEDRESKYFRVVTCSLLALKRLLCMLPRSEN-SSL 247

  Fly   257 KEGFGTLVAHQKFWSFAKHKVPAIKAAWFECIYHILQSVALLDVITPQKTQLTNLCFQFIDDADP 321
            :|....|::..|||.::||...:|::|:||.:..:.|...  ||:..:.::|.......|||:|.
 Frog   248 QERLAHLLSQSKFWKYSKHSTSSIRSAFFELMSALCQCSP--DVLRAEASRLCPAVLLSIDDSDA 310

  Fly   322 VVAPHIWGCVLLLQSNYVDWFVPLNIRKTLLPKLSSLLQNGFNRNAQAICPNLLPFLSKVTQASL 386
            ||.|.:|..||...:...|.:..:|.:|.:||||.|:|:.|....|..|.||||||:|:|....:
 Frog   311 VVCPALWEAVLYTITTIEDCWEHVNAQKGVLPKLWSVLREGGRGLATVIFPNLLPFISRVPTNII 375

  Fly   387 QDLDIYDFYQRFFDDMKLAVTKKFDPPLSKSDCIVIHNAYFECLRFLMQQINNNKQREQKEEEFS 451
            :...  |||..||:.:...::.: ....|.::|..|.:||.|||||.||:....::..:|.::..
 Frog   376 KTPT--DFYSNFFNSLGQGLSSE-RAVASPAECSAIISAYMECLRFAMQENAGEEEENKKVQQIL 437

  Fly   452 FS-----LLDNNVLEPIAWLLKSDSTHVKIFFQHSSALVAFWDRQINNR-LDN--GDLYAKLLNK 508
            .|     |:|:::.:|     |..::  .:|.|....|.: |:::..:: ||:  ..::|.||.:
 Frog   438 ISDQLMPLIDSSLKDP-----KLQNS--PLFSQVEETLYS-WEKKAESQGLDDKLSRIHATLLRE 494

  Fly   509 FWIRIFELVTQDLSAEEVNEQLLGHVLLLVQDLHMANPSL-----ESPSVKFVEGPNEKIEKSEP 568
            ||..:..:....:...|..|:.|..|..|:|.|...|..|     :...::|   ..|..::|:.
 Frog   495 FWENLAHICVSHVDVIEAGEKNLAGVSGLLQVLQNPNCLLKVNKKKKAKIRF---KGEDDDESDA 556

  Fly   569 TTPVKKAQEAAAFI-----------------QKELKQLVIKLVRICLDKANKGSGSGTSSSRYIE 616
            .:.|.::|..:.||                 |:.|:.||.||..:.:...     |...|.:::.
 Frog   557 VSHVSESQPMSKFIMETCSSSGRDPGIAQLRQERLEDLVCKLAELSMVYI-----SEQRSQQHLM 616

  Fly   617 QIRTLTKMFNDAAFYKSLTDDGDLASALN----------------------KFVSLLGQLSCQAC 659
            .:..|...|.....::.|..........|                      |.:......|.:..
 Frog   617 FLAALLSTFPSIRVFQVLLQQSSEEDPKNLNSPDHDVTPRHKNPAVQFLYAKLIFWFNDKSLEES 681

  Fly   660 ESVVEIVFEIL----------PLLETGKRFEYIENTLMKLPQHGVQN--------------LLLH 700
            :.:|:|::.:|          .||:...:..:..:..:.:.|....:              :|..
 Frog   682 DFLVDILYSVLFCCTDSSERKHLLDDMTKMNFKWSVFLYIIQKACTDPEKYSLASDWLKGEVLGE 746

  Fly   701 RL--LSYPLCAEAAVRQMLSGPETCE----MIARIAEE------VVVDNDREK-LNLLHKCFFQT 752
            ||  |:..||....:.:.......|.    :::.:..|      ::.|...|| :|.||..
 Frog   747 RLICLANDLCTSGLMDKATPSEAYCSKKWALLSLVLSEHVHNEYLIADAYVEKIINKLHSA---- 807

  Fly   753 DTGDILINAKTVDKILLSMCGPLEQPVVDDAVEVCGSFIAQIMPVICSNNNSSLHV--RQHIFLK 815
                 |:.|:.     ||..|.|||.|         |||..:.....|:....|.:  .:.:.|.
 Frog   808 -----LMKARN-----LSKAGHLEQSV---------SFICDVGSNFFSSIKGCLQMPSAEDLLLT 853

  Fly   816 LFKFSLEHRPEDYLSEDTLWEITTCWQDGLSS-----KDIEIDDDMLKCCAGIVEELANSAELKA 875
            :|:...:.....::||..|.::...|..||.|     |::....:.||..|..|::...::.|..
 Frog   854 IFQLCAQASDTSHMSESLLLKLKNTWLAGLHSLVCQYKNMPQGSNFLKQSAQWVKDQIQTSHLNV 918

  Fly   876 DTLDGMAEAMAKFVICSTENIEDEYKRLERIDETLTALLETPLKTTDKVQQFENHCVLLEALHGS 940
            .:|..:        ||:   ::|.|..:  :|.:|:........|...:...|....:..||
 Frog   919 KSLQSL--------ICT---VDDLYSTI--LDSSLSGFSLLAEHTASMMPSAETWQKMRHAL--- 967

  Fly   941 VTAGVPFENACLSRNEILPLLQ-RSTLNFSTIYKLVYQFPPPQDTNDPEDELTEDYCDPNADVLK 1004
                   .:..||:    |||: |.::|..|....:..|        |:..|....|  .|.:|.
 Frog   968 -------SSQWLSK----PLLEGRLSMNTETSGTDLKSF--------PKTWLPSHLC--TASLLS 1011

  Fly  1005 KWNEPLIAELLQCIRVAGTAECWLEMSVLQSS-------TEELVLILSEKVQSFMGNSSDL---V 1059
            |    :...||:..:.....|..:::::..:.       .|||     ||..:.:|...::   :
 Frog  1012 K----MALRLLEKEKSLKEEEIGVKINITVAEMLYSLQWCEEL-----EKPPTLIGECCEMLCSL 1067

  Fly  1060 AIVKERLQQAAVQQSSVIDCRLLSYLRFCPQYAAFEESASILLHE---------DLSENL----- 1110
            .:..|::...:|....:::   |.|.|.....:.:..:|:..:|:         .|:|:.
 Frog  1068 GVSHEKVMDLSVHLPGLLE---LLYNRSKEDGSLWSLTANRFIHKRGAGPSELLPLTEDTEKYFP 1129

  Fly  1111 VTQGALKTYVIALQFLLPKLSQKAI--------TLS-SAIMGTEPPEIWVKAAVFHALLLNNFEG 1166
            ||.|:|.|......|:.|:|.::.:        |.| ||:..|:       ....:..::|:..|
 Frog  1130 VTLGSLHTIQSLSAFMCPELKEELVIQCTARLMTCSASAVSCTD-------GGFGYLAIINSCLG 1187

  Fly  1167 DVNEQTDRNIIVSAVQFMTSIGERQASQKDLLHYNVEIQRQPYESVINTVEFIKLLTEVLKRFPY 1231
            . :....:.|:...::.|.|..:   .|:|:..::..:|......:...||.|:.|:.:||....
 Frog  1188 S-DSDLCQEILPGVLKVMLSWKD---DQEDIFLFSSNVQDSSQSLIGLNVEMIRFLSILLKYLAS 1248

  Fly  1232 ELSI---KNWDAIRIGLSSWVLSVSKSIAQYQDPKTSLFIVAVYELFAALIDFIRSEKQKSSTEL 1293
            .:|.   .:||.|...:.:|:.|..:|.|.|..|...||..|..:|...:..:..|....::..|
 Frog  1249 SVSSLVDVDWDFIMCSMLAWLESACESSAAYHIPLVRLFACASCDLATEISHYFESVATSTTMSL 1313

  Fly  1294 LKNMIDEWDSLFAKEVNLVLFKSYYLLTHEVSVDPGFQACYEALLEQITPVIER----------L 1348
            ..|::.||...|::.:..::......:..|      ::|...:.:..:...:.|          |
 Frog  1314 PANLMSEWKEFFSEGIYSLMLPMLVRIAEE------YKASETSHMSHVLKSLGRTLGYISKEQLL 1372

  Fly  1349 DYSFVYSFC---KSNSNITLDHLCNFLFKQLYSVQHSVRLSAVHSLRQL---TPHFVADDIELNE 1407
            ::.....|.   |:|...:|..|.|.|...|...:.||:::..|.|.::   .|.|..:|::...
 Frog  1373 NHKLPAKFVAGQKTNLTDSLQSLLNTLAPLLLYRERSVQITVYHLLDKIMADLPGFDDEDLKSYG 1437

  Fly  1408 KQSESLDASTTICKWHFLNRFEDYLTRYDALITKYLEEFTFKLSELDDLEPIDRH--NALSYLFL 1470
            .:.|....|........|...||       |:...|:|  ..:.|...:||:...  ..|.||..
 Frog  1438 DEDEEPALSPPAALMSVLAIQED-------LVESILKE--IPVGEFAVIEPLKEEFCFVLGYLLT 1493

  Fly  1471 WDCIINACAKSPVALRAVYTNWLNDNKYEENFLHFLFRAMPVD-ILKNHGAKVHSNG-------- 1526
            |..|:.....:...|||:|:.:|...|.....|:.||:.||.: :|....:.:.|..
 Frog  1494 WKLILTFFKAASSQLRALYSQYLRKTKSLNKLLYNLFKLMPHNPVLPGQASDMPSKEPKTFFTEE 1558

  Fly  1527 ---VYKELTWSQQKDRHLPLERYACHLYTEVLRKLPAVVRRWWNATQSRQKNFIDNLTTNYVSSL 1588
               ..|.....||:..||     ||.:|...|:.|||:||.|||..:.|..|.:|..||.||||:
 Frog  1559 LQLAVKGTATVQQEVPHL-----ACCVYHMTLKDLPAMVRLWWNGCEKRIFNVVDRFTTKYVSSV 1618

  Fly  1589 ICSEELKAIANRKEKHENMQVTVHSSTREVLAVYAIDEARMELVITLAPNYPLGAVKVECGKQIG 1653
            :.|:|:.::....:..:.|.|...|:||||:|.|::|:..:||:|.|..|||||::.||.|:::|
 Frog  1619 LSSQEISSVQLSTQVFDGMTVKARSTTREVIATYSVDDICIELIIQLPQNYPLGSITVESGRRVG 1683

  Fly  1654 GRASS-RNVGMQLTIFLTHQNGTIYDGLTMWKNNLDKKFEGVEECYVCYTVIHQETCQLPKLTCK 1717
            ..... ||..:||..:||||||:|.:||.:||||:||:|||||:|.:|::|||.....|||..|:
 Frog  1684 VAVQQWRNWMLQLNTYLTHQNGSIMEGLALWKNNVDKRFEGVEDCMICFSVIHGSNYSLPKKACR 1748

  Fly  1718 TCKKKFHGPCLYKWFTTSSKSTCPICRNVF 1747
            |||||||..|||||||:|:|||||:||..|
 Frog  1749 TCKKKFHSECLYKWFTSSNKSTCPLCRETF 1778

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ltn1	NP_730427.1	RING	<1724..1744	CDD:302633	15/20 (75%)
ltn1	XP_012812767.1	zf-RING_2	1726..1775	CDD:290367	31/49 (63%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C369929226
eggNOG	1	0.900				E1_COG5219
Hieranoid	1	1.000
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	481	1.000	Inparanoid score	I1340
OMA	1	1.010
OrthoDB	1	1.010				D19753at2759
OrthoFinder	1	1.000				FOG0003544
OrthoInspector	1	1.000				T1061055
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R672
TreeFam	1	0.960
	10	9.890