Protein Alignment: CG14085 and 2210408I21Rik

• Sequence 1: NP_649101.2
• Gene: CG14085
• FlyBaseID: FBgn0036859
• Length: 874
• Species: Drosophila melanogaster
• Sequence 2: NP_001139148.1
• Gene: 2210408I21Rik
• MGIID: 1919621
• Length: 1272
• Species: Mus musculus
• Alignment Length: 933
• Identity: 184/934 (20%)
• Similarity: 326/934 (35%)
• Gaps: 286/934 (31%)

  Fly    72 PSGLLHTEKEMNE--GDFSSVTVKTSD-----------------PDKFVQLVTKSADLLLEHIHR 117
            |.|.:..|:|..:  ..|.|..::..|                 .:..|:..:|.|..:||.:..
Mouse   469 PEGHIFPEEEQPKRVAKFCSDIIEKLDTMLLLALACRDDSPQEIKENLVEAYSKVATAVLERLQE 533

  Fly   118 LSQESLDHADLSVLTATIGAASLVKNSLSVYMQAATTTICPPKGDEKGGALKLSFKQYSQMSEAL 182
            ..:|....|.|..|.:.:.:|:.|....:.|......|...|       ...:..::|.:....:
Mouse   534 RGKEVPSRAPLKNLHSILSSATYVSQRFTHYDNLMKETTKKP-------IFLVPVQRYQEFINTV 591

  Fly   183 AERLLDLHCRLLLLYIMQDADCLHWEDTQPFFESERGSYTVQMWWHYMRGSQTDLWNSVPPKMAQ 247
            ..::.|...|:..:.|:|||:..||:|.:.|:|.||.|:.:|||.::......|||..:|||:||
Mouse   592 QFQVTDYCARVCAMSILQDAESHHWDDYKAFYEGERCSFAIQMWHYFSLALHHDLWTILPPKLAQ 656

  Fly   248 KIFAGMLNETLSVLTVRYTQIVTSVARSTLHLVDICNMLLCIAELLPHICESGEAYVGLQLSNQS 312
            :|.|.||.::|.:|..||.:...|..|:....:|:..:|:....:|..||.||:..:.....|..
Mouse   657 EILAEMLEKSLGLLASRYARAHPSPKRTAQIRLDVMAILIFTENMLWSICSSGQEILNPHKFNNH 721

  Fly   313 VIIRDIHAKCKELFYCLLLRGSPLGVLSKVFRKGLDNMEMFSSRHGL------PSAWIIFALPRY 371
            .|.: ||..|..||..|.:..|||..|.|.|:.|:|.    |..:.|      |..| |..:.::
Mouse   722 KIFK-IHTHCNNLFTTLAILTSPLTELYKTFQHGVDE----SPSNSLTPLFNQPLHW-ISCMSQF 780

  Fly   372 FP---KEQSCQWVTEFSDLSTNTAISLDLRVLLAFPEADWSYLLKILLMRDAYLTGIIMR----- 428
            :|   :..|...:|...          .|::||:.|...|:.||..||.....:..|:::
Mouse   781 YPSLLRPPSVGGLTAQG----------QLKLLLSQPCCKWNLLLDTLLHSGGLIPRILLKSSKQA 835

  Fly   429 ------------------------HLMQYLPSSENFKNVAKISFTSAEGAPQKCEAFLCRGECFN 469
                                    ||     ||:.|.||    |.|.....|..: ||     ||
Mouse   836 AGMESKQSAGGSLVGAIFEVLYHCHL-----SSQTFGNV----FMSHMEEEQLWD-FL-----FN 885

  Fly   470 VTDSIAGDIDPVG---QSNYQIVLSLTYLVV-----AVGKAVDIKSCLIKTLEEHAIAGWSDCLD 526
            :         ||.   :|..:::..|...::     .|.:.:.|..|. :..|.:.
Mouse   886 I---------PVSSFTESQPEVIHCLRLALMDSVKDTVQQIISIMRCR-RNSETNL--------- 931

  Fly   527 KRQVWNQKRTPWLEAIMHFMYPVLDCVVDMLVNAVENGASMY------------------QAMSL 573
                 |:.|.|                 |.|:.::..|.:..                  ||:|:
Mouse   932 -----NKPRVP-----------------DHLLQSIPQGWNYIPRDSRGKESNKGITELAAQAVSI 974

  Fly   574 ALTCVSEIWDCLPEGLYKIASLLQDIIPVSTRPLGDSVLLQVVFAALYTELIKTAEMYEQAKDLD 638
            .|:.:..:..|||..:.....|.:..:..:...|..:.||      ::..:|....::|....::
Mouse   975 VLSKLPTVIACLPPTIKYFFFLSERKMSKNLAELKKAGLL------VWNLIIIICRIFEDGNTVE 1033

  Fly   639 K--------------AAICYSISEAICSIDEDDKHTDQIELFLKQAK-----------ESINLDT 678
            :              ..||..:...:.......:.|.::.|.:::.|           .::::..
Mouse  1034 RLTGSSLDRWSKEKLGLICLCLESILGKQSNPSQLTQKVILSIERQKPNWMEQQLLKARTLSIQC 1098

  Fly   679 DFGGTAGSNNRGAGGMSAVSTIKMDDLALTNAESDRLSHSPPNNYAMELDVGIADYIAEVLVSDV 743
            .|  |....|.|:.|.:|:...:..    |||....|.|.|.
Mouse  1099 AF--TRMEENSGSEGEAALELTEQK----TNAMVLDLCHKPG----------------------- 1134

  Fly   744 LTTNIGKQALKVVYNYLKFNKDWLLEQLGTGDNDPSPFQGIQGQNIKEAKTSVLRSM-------- 800
                 |.:.|:.:|:.::.|:::|.|||             ...|..|.|..::|.:
Mouse  1135 -----GSKYLQQIYHIMQLNEEYLKEQL-------------FAMNGSEEKPLLIRPLKVALRDED 1181

  Fly   801 -----------FFIGNTPFDQLLTGSLKIDYVSWLQMPLSLN----------------------P 832
                       ..:..:..||:.|.:...|:.:.|...|.||                      .
Mouse  1182 QPPAFNPFHVHKVVSESMLDQVATVTWCCDWSNLLPNYLGLNKMTFGALFKNRWEMRKDETLEEK 1246

  Fly   833 ERTCL-HLNRRCDFQE----DAK 850
            |:..| ||.:.|..|:    |:|
Mouse  1247 EKMMLEHLKQNCTIQDFSTSDSK 1269

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14085	NP_649101.2	DUF4495	99..430	CDD:291567	92/369 (25%)
2210408I21Rik	NP_001139148.1	DUF4495	515..832	CDD:291567	91/340 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E1_2CA28
Hieranoid	1	1.000
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000				FOG0007219
OrthoInspector	1	1.000				T1085100
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100			LDO	PTHR33960
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R5691
TreeFam	1	0.960
	7	6.990