Protein Alignment CG14085 and 2210408I21Rik

DIOPT Version :10

• Sequence 1: NP_649101.2
• Gene: CG14085 / 40099
• FlyBaseID: FBgn0036859
• Length: 874
• Species: Drosophila melanogaster
• Sequence 2: XP_036014072.1
• Gene: 2210408I21Rik / 72371
• MGIID: 1919621
• Length: 1290
• Species: Mus musculus
• Alignment Length: 887
• Identity: 176/887 - (19%)
• Similarity: 314/887 - (35%)
• Gaps: 259/887 - (29%)

  Fly    72 PSGLLHTEKEMNE--GDFSSVTVKTSD-----------------PDKFVQLVTKSADLLLEHIHR 117
            |.|.:..|:|..:  ..|.|..::..|                 .:..|:..:|.|..:||.:..
Mouse   469 PEGHIFPEEEQPKRVAKFCSDIIEKLDTMLLLALACRDDSPQEIKENLVEAYSKVATAVLERLQE 533

  Fly   118 LSQESLDHADLSVLTATIGAASLVKNSLSVYMQAATTTICPPKGDEKGGALKLSFKQYSQMSEAL 182
            ..:|....|.|..|.:.:.:|:.|....:.|......|...|       ...:..::|.:....:
Mouse   534 RGKEVPSRAPLKNLHSILSSATYVSQRFTHYDNLMKETTKKP-------IFLVPVQRYQEFINTV 591

  Fly   183 AERLLDLHCRLLLLYIMQDADCLHWEDTQPFFESERGSYTVQMWWHYMRGSQTDLWNSVPPKMAQ 247
            ..::.|...|:..:.|:|||:..||:|.:.|:|.||.|:.:|||.::......|||..:|||:||
Mouse   592 QFQVTDYCARVCAMSILQDAESHHWDDYKAFYEGERCSFAIQMWHYFSLALHHDLWTILPPKLAQ 656

  Fly   248 KIFAGMLNETLSVLTVRYTQIVTSVARSTLHLVDICNMLLCIAELLPHICESGEAYVGLQLSNQS 312
            :|.|.||.::|.:|..||.:...|..|:....:|:..:|:....:|..||.||:..:.....|..
Mouse   657 EILAEMLEKSLGLLASRYARAHPSPKRTAQIRLDVMAILIFTENMLWSICSSGQEILNPHKFNNH 721

  Fly   313 VIIRDIHAKCKELFYCLLLRGSPLGVLSKVFRKGLDNMEMFSSRHGL------PSAWIIFALPRY 371
            .|.: ||..|..||..|.:..|||..|.|.|:.|:|.    |..:.|      |..| |..:.::
Mouse   722 KIFK-IHTHCNNLFTTLAILTSPLTELYKTFQHGVDE----SPSNSLTPLFNQPLHW-ISCMSQF 780

  Fly   372 FP---KEQSCQWVTEFSDLSTNTAISLDLRVLLAFPEADWSYLLKILLMRDAYLTGIIMR----- 428
            :|   :..|...:|...          .|::||:.|...|:.||..||.....:..|:::
Mouse   781 YPSLLRPPSVGGLTAQG----------QLKLLLSQPCCKWNLLLDTLLHSGGLIPRILLKSSKQA 835

  Fly   429 ------------------------HLMQYLPSSENFKNVAKISFTSAEGAPQKCEAFLCRGECFN 469
                                    ||     ||:.|.||    |.|.....|..: ||     ||
Mouse   836 AGMESKQSAGGSLVGAIFEVLYHCHL-----SSQTFGNV----FMSHMEEEQLWD-FL-----FN 885

  Fly   470 VTDSIAGDIDPVG---QSNYQIVLSLTYLVV-----AVGKAVDIKSCLIKTLEEHAIAGWSDCLD 526
            :         ||.   :|..:::..|...::     .|.:.:.|..|. :..|.:.
Mouse   886 I---------PVSSFTESQPEVIHCLRLALMDSVKDTVQQIISIMRCR-RNSETNL--------- 931

  Fly   527 KRQVWNQKRTPWLEAIMHFMYPVLDCVVDMLVNAVENGASMY------------------QAMSL 573
                 |:.|.|                 |.|:.::..|.:..                  ||:|:
Mouse   932 -----NKPRVP-----------------DHLLQSIPQGWNYIPRDSRGKESNKGITELAAQAVSI 974

  Fly   574 ALTCVSEIWDCLPEGLYKIASLLQDIIPVSTRPLGDSVLLQVVFAALYTELIKTAEMYEQAKDLD 638
            .|:.:..:..|||..:.....|.:..:..:...|..:.||      ::..:|....::|....::
Mouse   975 VLSKLPTVIACLPPTIKYFFFLSERKMSKNLAELKKAGLL------VWNLIIIICRIFEDGNTVE 1033

  Fly   639 K--------------AAICYSISEAICSIDEDDKHTDQIELFLKQAK-----------ESINLDT 678
            :              ..||..:...:.......:.|.::.|.:::.|           .::::..
Mouse  1034 RLTGSSLDRWSKEKLGLICLCLESILGKQSNPSQLTQKVILSIERQKPNWMEQQLLKARTLSIQC 1098

  Fly   679 DFGGTAGSNNRGAGGMSAVSTIKMDDLALTNAESDRLSHSPPNNYAMELDVGIADYIAEVLVSDV 743
            .|  |....|.|:.|.:|:...:..    |||....|.|.|.
Mouse  1099 AF--TRMEENSGSEGEAALELTEQK----TNAMVLDLCHKPG----------------------- 1134

  Fly   744 LTTNIGKQALKVVYNYLKFNKDWLLEQLGTGDNDPSPFQGIQGQNIKEAKTSVLRSM-------- 800
                 |.:.|:.:|:.::.|:::|.|||             ...|..|.|..::|.:
Mouse  1135 -----GSKYLQQIYHIMQLNEEYLKEQL-------------FAMNGSEEKPLLIRPLKVALRDED 1181

  Fly   801 -----------FFIGNTPFDQLLTGSLKIDYVSWLQMPLSLN 831
                       ..:..:..||:.|.:...|:.:.|...|.||
Mouse  1182 QPPAFNPFHVHKVVSESMLDQVATVTWCCDWSNLLPNYLGLN 1223

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14085	NP_649101.2	DUF4495	99..430	CDD:464363	91/368 (25%)
2210408I21Rik	XP_036014072.1	DUF4495	515..832	CDD:464363	91/339 (27%)