Protein Alignment CG14085 and Kiaa0825

DIOPT Version :10

• Sequence 1: NP_649101.2
• Gene: CG14085 / 40099
• FlyBaseID: FBgn0036859
• Length: 874
• Species: Drosophila melanogaster
• Sequence 2: XP_017446642.1
• Gene: Kiaa0825 / 294603
• RGDID: 1560883
• Length: 1303
• Species: Rattus norvegicus
• Alignment Length: 854
• Identity: 181/854 - (21%)
• Similarity: 310/854 - (36%)
• Gaps: 201/854 - (23%)

  Fly   101 VQLVTKSADLLLEHIHRLSQESLDHADLSVLTATIGAASLVKNSLSVYMQAATTTICPPKGDEKG 165
            |:...|.|..:||.:.....|....|.|..|...:.:|..:......|......|...|
  Rat   547 VEACCKVATAVLERLRERGTEVPSRAPLKNLHIILSSAVYISQWFMHYDNLMKETAKKP------ 605

  Fly   166 GALKLSFKQYSQMSEALAERLLDLHCRLLLLYIMQDADCLHWEDTQPFFESERGSYTVQMWWHYM 230
             ...:..::|.:....:..:|.|...|:....|:|||:..||||.:.|:|.||.|:.:|||.::.
  Rat   606 -IFLVPVQRYQEFISTVQFQLTDYCIRVCATSILQDAESHHWEDYKAFYEGERCSFAIQMWHYFS 669

  Fly   231 RGSQTDLWNSVPPKMAQKIFAGMLNETLSVLTVRYTQIVTSVARSTLHLVDICNMLLCIAELLPH 295
            .....|||..:|||:||:|.|.:|.::|.:|..||.:...|..|:....:||..:|:|..::|..
  Rat   670 WALHHDLWTILPPKLAQEILAELLEKSLGLLASRYARAHPSPRRTAQIRLDITAILICTEKMLWS 734

  Fly   296 ICESGEAYVGLQLSNQSVIIRDIHAKCKELFYCLLLRGSPLGVLSKVFRKGLDN--MEMFSSRHG 358
            :|.|.:..:.....|...|.: ||..|..||..|.:..|||..|.|.|:.|.|.  ...|:....
  Rat   735 VCTSEQEILNPHKYNHHKIFK-IHIHCNNLFTTLAILTSPLTELYKTFQDGRDESASNAFTPLFN 798

  Fly   359 LPSAWIIFALPRYFPKEQSCQWVTEF--SDLSTNTAISL----DLRVLLAFPEADWSYLLKILLM 417
            .|..||            ||  :::|  |.|...:|..|    .|::||:.|....:.||:.||.
  Rat   799 QPLHWI------------SC--LSQFHPSLLRPPSARELTAQGQLKLLLSQPCCKGNLLLETLLH 849

  Fly   418 RDAYLTGIIMRHLMQ-------------------------YLPSSENFKNVAKISFTSAEGAPQK 457
            .|..:..|:::...|                         :| |.:.|.||    |||.....|.
  Rat   850 GDGLIARILLKSAKQAAGMESKQSAGCSVVGTIFEVLYWCHL-SPQTFGNV----FTSHMEEEQL 909

  Fly   458 CEAFLCRGECFNVTDSIAGDIDPVGQSNYQIVLSLTYLVV-----AVGKAVDIKSCLIKTLEEHA 517
            .: |||     |:..|...:..|      :::..|...::     .|.:.:.:..|
  Rat   910 WD-FLC-----NIPVSAFTESQP------EVIRCLRLALIDSVKDTVQQIISMVKC--------- 953

  Fly   518 IAGWSDC---LDKRQV-----------WN--QKRTPWLEAIMHFMYPVLDCVVDMLVNAVENGAS 566
               |.:.   |:|..|           ||  .:.:.|.|:...|.                  ..
  Rat   954 ---WRNSETKLNKPPVPDHLLQSIPREWNYIPRDSTWKESNKGFT------------------RL 997

  Fly   567 MYQAMSLALTCVSEIWDCLPEGLYKIASLLQDIIPVSTRPLGDSVLLQVVFAALYTELIKTAEMY 631
            ..||:|:.|:.:..:..|||..:.....|.:..:..:...|..:.||......:...:.:.....
  Rat   998 AAQAVSIVLSKLPTVIACLPPTIKYFFFLSERKMSKNVAELKKAGLLVWNLIVIICRIFEDGNTV 1062

  Fly   632 EQ--AKDLDK------AAICYSISEAICSIDEDDKHTDQIELFLKQAK-----------ESINLD 677
            |:  ...||:      ..||..:...:.......:.|.::.|.::|..           .::|::
  Rat  1063 ERLTGSSLDRWSKEKLGLICLCLESILGEQSSPSQLTQKVILHIEQQSPNWIEHQLLKARTLNIE 1127

  Fly   678 TDFGGTAGSNNRGAGGMSAVSTIKMDDLALTNAESDRLSHSPPNNYAMELDVGIADYIAEVLVSD 742
                 .|.....|:.|....:.:::.: ..|||....|.|.|.
  Rat  1128 -----CASMPVEGSSGSEGDAVLELTE-QKTNAMVLDLCHKPG---------------------- 1164

  Fly   743 VLTTNIGKQALKVVYNYLKFNKDWLLEQL---GTGDNDPSPFQGIQGQNIKEAKTSVLRSMFF-- 802
                  |.:.|:.:|:.::.|:::|.|||   ...:..|.|.     |.:|||    ||:..:
  Rat  1165 ------GSKYLQQIYHIMQLNEEYLKEQLLAMNGSEEKPFPI-----QPLKEA----LRNGEYQP 1214

  Fly   803 -----------IGNTPFDQLLTGSLKIDYVSWLQMPLSLNPERTCLHLNRRCDFQEDAKLSLPEV 856
                       ...:..||..|.:...|:.:.|...|.|:.......|..|.:.::|..|...|.
  Rat  1215 PAFDPFHVHKVFSESMLDQAATATWYWDWSNLLPNYLGLDKMTFGPLLKNRWEMRKDETLEKNEK 1279

  Fly   857 AMVAGITKI 865
            .|:..:.:|
  Rat  1280 MMLEHLKQI 1288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14085	NP_649101.2	DUF4495	99..430	CDD:464363	94/336 (28%)
Kiaa0825	XP_017446642.1	DUF4495	545..861	CDD:464363	94/335 (28%)