Protein Alignment Aldh7A1 and adhE

DIOPT Version :10

• Sequence 1: NP_649099.1
• Gene: Aldh7A1 / 40097
• FlyBaseID: FBgn0036857
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_415757.1
• Gene: adhE / 945837
• ECOCYCID: EG10031
• Length: 891
• Species: Escherichia coli
• Alignment Length: 540
• Identity: 105/540 - (19%)
• Similarity: 201/540 - (37%)
• Gaps: 135/540 - (25%)

  Fly    82 NVQELEHTIGLAVEAYKQWRQVPAPVRGEIVRQIGDELRKYKEPLGKLVSLEVGKIYSEGQGEVQ 146
            ||.||...:....:|.:::.........:|.|.........:.||.|:...|      .|.|.|:
E. coli     5 NVAELNALVERVKKAQREYASFTQEQVDKIFRAAALAAADARIPLAKMAVAE------SGMGIVE 63

  Fly   147 EFIDICDYAVGLSRIYSGQLINSERADHSILEAWR---------------------PLGVV-GVI 189
            :                 ::|.:..|...|..|::                     |:|:: |::
E. coli    64 D-----------------KVIKNHFASEYIYNAYKDEKTCGVLSEDDTFGTITIAEPIGIICGIV 111

  Fly   190 SAYNFPNAVFGWNAAIALTTGNSVLWKGAPSTPLVSVATTKIVAEVLRRNNLPP--VVTLCQGGT 252
            ...| |.:...:.:.|:|.|.|::::...|.....:.....||.:.......|.  :..:.|...
E. coli   112 PTTN-PTSTAIFKSLISLKTRNAIIFSPHPRAKDATNKAADIVLQAAIAAGAPKDLIGWIDQPSV 175

  Fly   253 DVGQTLVADKRVNLVSFTGSCQTGRDVGVEVQRRFGKVILELG-GNNALIIDESANVKMALDAAL 316
            ::...|:....:||:..||    |..: |:.....||..:.:| ||..::|||:|::|.|:.:.|
E. coli   176 ELSNALMHHPDINLILATG----GPGM-VKAAYSSGKPAIGVGAGNTPVVIDETADIKRAVASVL 235

  Fly   317 FGCIGTSGQRCTTTRRIIVHEKLHDQFVKELVGKYKQLISKIGHQLEAQTLVGPVHTQQNVENYK 381
            ......:|..|.:.:.::|.:.::|. |:|....:...:.: |.:|:|   |..|..:....|
E. coli   236 MSKTFDNGVICASEQSVVVVDSVYDA-VRERFATHGGYLLQ-GKELKA---VQDVILKNGALN-- 293

  Fly   382 AAIAEAKSLGGTVAFGGNVIQRDGFYV---------EPTVITGLPHDASVVHRETFAPIVYILKA 437
            |||.      |..|:  .:.:..||.|         |.||:    .::.....|..:|.:.:.:|
E. coli   294 AAIV------GQPAY--KIAELAGFSVPENTKILIGEVTVV----DESEPFAHEKLSPTLAMYRA 346

  Fly   438 KNVDQAIEWNNEVEQ-------GLSSAIFTENIGQAFK--WIGAKGSDCGIVNINTTTNGAEIG- 492
            |:.:.|:|   :.|:       |.:|.::|:...|..:  :.|.|.....|: |||..:...||
E. coli   347 KDFEDAVE---KAEKLVAMGGIGHTSCLYTDQDNQPARVSYFGQKMKTARIL-INTPASQGGIGD 407

  Fly   493 --------------GAFGGEKATGG------------GRESGSDAWKQ-----YCKRAT------ 520
                          |::||...:..            .:.:.:..|.:     |.:|.:
E. coli   408 LYNFKLAPSLTLGCGSWGGNSISENVGPKHLINKKTVAKRAENMLWHKLPKSIYFRRGSLPIALD 472

  Fly   521 --ITVNHSGELACAQGVVFN 538
              ||..|...|......:||
E. coli   473 EVITDGHKRALIVTDRFLFN 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh7A1	NP_649099.1	ALDH_F7_AASADH	51..526	CDD:143448	101/526 (19%)
adhE	NP_415757.1	PRK13805	1..862	CDD:237515	105/540 (19%)