Protein Alignment Aldh7A1 and ALD5

DIOPT Version :10

• Sequence 1: NP_649099.1
• Gene: Aldh7A1 / 40097
• FlyBaseID: FBgn0036857
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_010996.2
• Gene: ALD5 / 856804
• SGDID: S000000875
• Length: 520
• Species: Saccharomyces cerevisiae
• Alignment Length: 463
• Identity: 132/463 - (28%)
• Similarity: 225/463 - (48%)
• Gaps: 21/463 - (4%)

  Fly    68 DPGTGQPIAKVRQGNVQELEHTIGLAVEAYK-QWRQVPAPVRGEIVRQIGDELRKYKEPLGKLVS 131
            :|...:.|..|.:....:::..:..|.:|:: :|..|...||.:.:..:.|.:.|::|.|..:.|
Yeast    65 NPSNEEKITTVYKAMEDDVDEAVAAAKKAFETKWSIVEPEVRAKALFNLADLVEKHQETLAAIES 129

  Fly   132 LEVGKIYSEGQGE---VQEFIDIC-DYAVGLSRIYSGQLINSERADHSILEAWRPLGVVGVISAY 192
            ::.||.....:|:   |.:::..| .:|   .:|| |.:|::.: :|.......||||.|.|..:
Yeast   130 MDNGKSLFCARGDVALVSKYLRSCGGWA---DKIY-GNVIDTGK-NHFTYSIKEPLGVCGQIIPW 189

  Fly   193 NFPNAVFGWNAAIALTTGNSVLWKGAPSTPLVSVATTKIVAEVLRRNNLPP-VVTLCQG-GTDVG 255
            |||..::.|....||.|||:|:.|.|.:|||.::..:::..|.    .:|. ||.:..| |..||
Yeast   190 NFPLLMWSWKIGPALATGNTVVLKPAETTPLSALFASQLCQEA----GIPAGVVNILPGSGRVVG 250

  Fly   256 QTLVADKRVNLVSFTGSCQTGRDVGVEVQRRFGKVILELGGNNALIIDESANVKMALDAALFGCI 320
            :.|.|...|..::||||..|||.:.........||.|||||.:..|:...|::..|:....||..
Yeast   251 ERLSAHPDVKKIAFTGSTATGRHIMKVAADTVKKVTLELGGKSPNIVFADADLDKAVKNIAFGIF 315

  Fly   321 GTSGQRCTTTRRIIVHEKLHDQFVKELVGKYKQLISKIGHQLEAQTLVGPVHTQQNVENYKAAIA 385
            ..||:.|....||.:.:.::::.:::|....:.|  |:|...:.:...|...:.:.:......:.
Yeast   316 YNSGEVCCAGSRIYIQDTVYEEVLQKLKDYTESL--KVGDPFDEEVFQGAQTSDKQLHKILDYVD 378

  Fly   386 EAKSLGGTVAFGGNVIQRDGFYVEPTVITGLPHDASVVHRETFAPIVYILKAKNVDQAIEWNNEV 450
            .|||.|..:..||......|::|:|||...:..|..:|..|.|.|||.:.|...||:.|...|:.
Yeast   379 VAKSEGARLVTGGARHGSKGYFVKPTVFADVKEDMRIVKEEVFGPIVTVSKFSTVDEVIAMANDS 443

  Fly   451 EQGLSSAIFTENIGQAFKWIGAKGSDCGIVNINTTTNGAEIGGAFGGEKATGGGRESGSDAWKQY 515
            :.||::.|.|.:|.:|..  .:|....|.|.|||..|..: ...|||...:|.|||.|..|...|
Yeast   444 QYGLAAGIHTNDINKAVD--VSKRVKAGTVWINTYNNFHQ-NVPFGGFGQSGIGREMGEAALSNY 505

  Fly   516 CKRATITV 523
            .:..::.:
Yeast   506 TQTKSVRI 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh7A1	NP_649099.1	ALDH_F7_AASADH	51..526	CDD:143448	132/463 (29%)
ALD5	NP_010996.2	ALDH_F1-2_Ald2-like	41..513	CDD:143410	132/461 (29%)