Protein Alignment Aldh7A1 and ALD2

DIOPT Version :10

• Sequence 1: NP_649099.1
• Gene: Aldh7A1 / 40097
• FlyBaseID: FBgn0036857
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_013893.1
• Gene: ALD2 / 855206
• SGDID: S000004780
• Length: 506
• Species: Saccharomyces cerevisiae
• Alignment Length: 529
• Identity: 142/529 - (26%)
• Similarity: 244/529 - (46%)
• Gaps: 69/529 - (13%)

  Fly    32 IDQPEYSFLKELGLERDNPGVYSGQWQGRGPSVTSYDPGTGQPIAKVRQGNVQELEHTIGLAVEA 96
            |.|.:.|..:.|||..:|....|..    |.::.:.:|.||:||...:..|.::::..:..|..|
Yeast    10 IPQLKISLKQPLGLFINNEFCPSSD----GKTIETVNPATGEPITSFQAANEKDVDKAVKAARAA 70

  Fly    97 YKQ-WRQVPAPVRGEIVRQIGDELRKYKEPLGKLVSLEVGKIY-SEGQGEVQEFIDICDYAVGLS 159
            :.. |.:..:..||..:..:...:.:.::.|..|.:|:.||.| |..:|::.:.:.:..|..|
Yeast    71 FDNVWSKTSSEQRGIYLSNLLKLIEEEQDTLAALETLDAGKPYHSNAKGDLAQILQLTRYFAG-- 133

  Fly   160 RIYSGQLINSERADHS------------ILEAWRPLGVVGVISAYNFPNAVFGWNAAIALTTGNS 212
                    ::::.|..            .|:.  |.|||..|..:|:|.|:..|....||..||:
Yeast   134 --------SADKFDKGATIPLTFNKFAYTLKV--PFGVVAQIVPWNYPLAMACWKLQGALAAGNT 188

  Fly   213 VLWKGAPSTPLVSVATTKIVAEVLRRNNLPP-VVTLCQG-GTDVGQTLVADKRVNLVSFTGSCQT 275
            |:.|.|.:|.|    :....|.::::...|| ||.:..| |:.|||.|.:...::.:|||||.:.
Yeast   189 VIIKPAENTSL----SLLYFATLIKKAGFPPGVVNIVPGYGSLVGQALASHMDIDKISFTGSTKV 249

  Fly   276 GRDVGVEV--QRRFGKVILELGGNNALIIDESANVKMALDAALFGCIGTSGQRCTTTRRIIVHEK 338
            |..| :|.  |.....|.||.||.:..::.|.|::..|:|....|....|||.||...|:.|...
Yeast   250 GGFV-LEASGQSNLKDVTLECGGKSPALVFEDADLDKAIDWIAAGIFYNSGQNCTANSRVYVQSS 313

  Fly   339 LHDQFV---KELVGKYKQLISKIGHQLEAQTLVGPVHTQQNVENYKAAIAEAK------------ 388
            ::|:||   ||...|...:..|. ...:.:.:||||.:....:..|:.|...|
Yeast   314 IYDKFVEKFKETAKKEWDVAGKF-DPFDEKCIVGPVISSTQYDRIKSYIERGKREEKLDMFQTSE 377

  Fly   389 -SLGGTVAFGGNVIQRDGFYVEPTVITGLPHDASVVHRETFAPIVYILKAKNVDQAIEWNNEVEQ 452
             .:||.          .|:::.||:.|.:|..:.::..|.|.|:|.:.|..|.|.|::..|:...
Yeast   378 FPIGGA----------KGYFIPPTIFTDVPQTSKLLQDEIFGPVVVVSKFTNYDDALKLANDTCY 432

  Fly   453 GLSSAIFTENIGQAFKWIGAKGSDCGIVNINTTTNGAEIGGAFGGEKATGGGRESGSDAWKQYCK 517
            ||:||:||:::.:|..:  |:....|.|.|| ::|..::...|||.|.:|.|||.|......|.:
Yeast   433 GLASAVFTKDVKKAHMF--ARDIKAGTVWIN-SSNDEDVTVPFGGFKMSGIGRELGQSGVDTYLQ 494

  Fly   518 RATITVNHS 526
            ...:.:|.|
Yeast   495 TKAVHINLS 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh7A1	NP_649099.1	ALDH_F7_AASADH	51..526	CDD:143448	134/508 (26%)
ALD2	NP_013893.1	ALDH_ALD2-YMR170C	14..502	CDD:143462	138/522 (26%)