Protein Alignment Aldh7A1 and ALD3

DIOPT Version :10

• Sequence 1: NP_649099.1
• Gene: Aldh7A1 / 40097
• FlyBaseID: FBgn0036857
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_013892.1
• Gene: ALD3 / 855205
• SGDID: S000004779
• Length: 506
• Species: Saccharomyces cerevisiae
• Alignment Length: 520
• Identity: 140/520 - (26%)
• Similarity: 244/520 - (46%)
• Gaps: 51/520 - (9%)

  Fly    32 IDQPEYSFLKELGLERDNPGVYSGQWQGRGPSVTSYDPGTGQPIAKVRQGNVQELEHTIGLAVEA 96
            |.|.:.|..:.|||..:|....|..    |.::.:.:|.||:||...:..|.::::..:..|..|
Yeast    10 IPQLKISLKQPLGLFINNEFCPSSD----GKTIETVNPATGEPITSFQAANEKDVDKAVKAARAA 70

  Fly    97 YKQ-WRQVPAPVRGEIVRQIGDELRKYKEPLGKLVSLEVGK-IYSEGQGEVQEFIDICDYAVG-L 158
            :.. |.:..:..||..:..:...:.:.::.|..|.:|:.|| .:|..:.::.:.|::..|..| :
Yeast    71 FDNVWSKTSSEQRGIYLSNLLKLIEEEQDTLAALETLDAGKPFHSNAKQDLAQIIELTRYYAGAV 135

  Fly   159 SRIYSGQLI--NSERADHSILEAWRPLGVVGVISAYNFPNAVFGWNAAIALTTGNSVLWKGAPST 221
            .:...|:.|  ...:..:::..   |.|||..|..:|:|.|:.......||..||:|:.|.|.:|
Yeast   136 DKFNMGETIPLTFNKFAYTLKV---PFGVVAQIVPWNYPLAMACRKMQGALAAGNTVIIKPAENT 197

  Fly   222 PLVSVATTKIVAEVLRRNNLPP-VVTLCQG-GTDVGQTLVADKRVNLVSFTGSCQTGRDVGVEV- 283
            .|    :....|.::::...|| ||.:..| |:.||:.|.....::.:|||||.:.|..| :|.
Yeast   198 SL----SLLYFATLIKKAGFPPGVVNVIPGYGSVVGKALGTHMDIDKISFTGSTKVGGSV-LEAS 257

  Fly   284 -QRRFGKVILELGGNNALIIDESANVKMALDAALFGCIGTSGQRCTTTRRIIVHEKLHDQFV--- 344
             |.....:.||.||.:..::.|.|::..|::....|....|||.||...|:.|...::|:||
Yeast   258 GQSNLKDITLECGGKSPALVFEDADLDKAIEWVANGIFFNSGQICTANSRVYVQSSIYDKFVEKF 322

  Fly   345 KELVGKYKQLISKIGHQLEAQTLVGPVHTQQNVENYKAAIAEAKS-------------LGGTVAF 396
            ||...|...:..|. ...:.:.:||||.:....:..|:.|...|.             :||.
Yeast   323 KETAKKEWDVAGKF-DPFDEKCIVGPVISSTQYDRIKSYIERGKKEEKLDMFQTSEFPIGGA--- 383

  Fly   397 GGNVIQRDGFYVEPTVITGLPHDASVVHRETFAPIVYILKAKNVDQAIEWNNEVEQGLSSAIFTE 461
                   .|:::.||:.|.:|..:.::..|.|.|:|.:.|..|.|.|::..|:...||:||:||:
Yeast   384 -------KGYFIPPTIFTDVPETSKLLRDEIFGPVVVVSKFTNYDDALKLANDTCYGLASAVFTK 441

  Fly   462 NIGQAFKWIGAKGSDCGIVNINTTTNGAEIGGAFGGEKATGGGRESGSDAWKQYCKRATITVNHS 526
            ::.:|..:  |:....|.|.|| .||..|....|||.|.:|.|||||......|.:..::.|:.|
Yeast   442 DVKKAHMF--ARDIKAGTVWIN-QTNQEEAKVPFGGFKMSGIGRESGDTGVDNYLQIKSVHVDLS 503

  Fly   527  526
            Yeast   504  503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh7A1	NP_649099.1	ALDH_F7_AASADH	51..526	CDD:143448	132/499 (26%)
ALD3	NP_013892.1	ALDH-SF	14..502	CDD:448367	137/513 (27%)