Protein Alignment Aldh7A1 and ALD4

DIOPT Version :10

• Sequence 1: NP_649099.1
• Gene: Aldh7A1 / 40097
• FlyBaseID: FBgn0036857
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_015019.1
• Gene: ALD4 / 854556
• SGDID: S000005901
• Length: 519
• Species: Saccharomyces cerevisiae
• Alignment Length: 516
• Identity: 149/516 - (28%)
• Similarity: 243/516 - (47%)
• Gaps: 32/516 - (6%)

  Fly     4 QLRNISKLALPRRLVTQTASYSSSSSYLIDQPEYSFLKELGLERDNPGVYSGQWQGRGPSVTSYD 68
            |||..|.|.:       |......:....:||       .||..:|..|.|.|    ..:....:
Yeast    20 QLRYFSHLPM-------TVPIKLPNGLEYEQP-------TGLFINNKFVPSKQ----NKTFEVIN 66

  Fly    69 PGTGQPIAKVRQGNVQELEHTIGLAVEAYK--QWRQVPAPVRGEIVRQIGDELRKYKEPLGKLVS 131
            |.|.:.|..:.:|...::|..:..|..|:.  .|..:....||:.:.::.:.:.:.|:.:..:.:
Yeast    67 PSTEEEICHIYEGREDDVEEAVQAADRAFSNGSWNGIDPIDRGKALYRLAELIEQDKDVIASIET 131

  Fly   132 LEVGKIYSEGQGEVQEFIDICDYAVGLSRIYSGQLINSERADHSILEAWRPLGVVGVISAYNFPN 196
            |:.||..|..:|:|...|:....:.|.:....|::|::.|...|..:. :||||.|.|..:|||.
Yeast   132 LDNGKAISSSRGDVDLVINYLKSSAGFADKIDGRMIDTGRTHFSYTKR-QPLGVCGQIIPWNFPL 195

  Fly   197 AVFGWNAAIALTTGNSVLWKGAPSTPLVSVATTKIVAEVLRRNNLPP-VVTLCQG-GTDVGQTLV 259
            .::.|..|.||.|||:|:.|.|.||||.::..:|.:.:.    .:|| |:.:..| |..||:.:.
Yeast   196 LMWAWKIAPALVTGNTVVLKTAESTPLSALYVSKYIPQA----GIPPGVINIVSGFGKIVGEAIT 256

  Fly   260 ADKRVNLVSFTGSCQTGRDVGVEVQRRFGKVILELGGNNALIIDESANVKMALDAALFGCIGTSG 324
            ...::..|:||||..|||.:.........||.|||||.:..|:...|.:|.|:...:.|....||
Yeast   257 NHPKIKKVAFTGSTATGRHIYQSAAAGLKKVTLELGGKSPNIVFADAELKKAVQNIILGIYYNSG 321

  Fly   325 QRCTTTRRIIVHEKLHDQFVKELVGKYKQLISKIGHQLEAQTLVGPVHTQQNVENYKAAIAEAKS 389
            :.|....|:.|.|.::|:|::|.....:.:  |:|...:..|..|...:|..:......:...|:
Yeast   322 EVCCAGSRVYVEESIYDKFIEEFKAASESI--KVGDPFDESTFQGAQTSQMQLNKILKYVDIGKN 384

  Fly   390 LGGTVAFGGNVIQRDGFYVEPTVITGLPHDASVVHRETFAPIVYILKAKNVDQAIEWNNEVEQGL 454
            .|.|:..||..:...|::::|||...:..|..:|..|.|.|:|.:.|.|:.|:.|...|:.|.||
Yeast   385 EGATLITGGERLGSKGYFIKPTVFGDVKEDMRIVKEEIFGPVVTVTKFKSADEVINMANDSEYGL 449

  Fly   455 SSAIFTENIGQAFKWIGAKGSDCGIVNINTTTNGAEIGGAFGGEKATGGGRESGSDAWKQY 515
            ::.|.|.||..|.|  .|...:.|.|.|| |.|.......|||..|:|.|||...||.:.|
Yeast   450 AAGIHTSNINTALK--VADRVNAGTVWIN-TYNDFHHAVPFGGFNASGLGREMSVDALQNY 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh7A1	NP_649099.1	ALDH_F7_AASADH	51..526	CDD:143448	138/469 (29%)
ALD4	NP_015019.1	ALDH_F1-2_Ald2-like	42..514	CDD:143410	143/487 (29%)