Protein Alignment Aldh7A1 and ALDH3A1

DIOPT Version :10

• Sequence 1: NP_649099.1
• Gene: Aldh7A1 / 40097
• FlyBaseID: FBgn0036857
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: XP_047291551.1
• Gene: ALDH3A1 / 218
• HGNCID: 405
• Length: 570
• Species: Homo sapiens
• Alignment Length: 322
• Identity: 75/322 - (23%)
• Similarity: 150/322 - (46%)
• Gaps: 27/322 - (8%)

  Fly   208 TTGNSVLWKGAPSTPLVSVATTKIVAEVLRRNNLPPVVTLCQGGTDVGQTLVADKRVNLVSFTGS 272
            :.||||:.|.:..:..::.....|:.:.|.: :|.||:   .||......|:.: |.:.:.:|||
Human   247 SAGNSVVLKPSELSENMASLLATIIPQYLDK-DLYPVI---NGGVPETTELLKE-RFDHILYTGS 306

  Fly   273 CQTGRDVGVEVQRRFGKVILELGGNNALIIDESANVKMALDAALFGCIGTSGQRCTTTRRIIVHE 337
            ...|:.:.....:....|.|||||.:...:|::.::.:|.....:|....|||.|.....|:...
Human   307 TGVGKIIMTAAAKHLTPVTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNSGQTCVAPDYILCDP 371

  Fly   338 KLHDQFVKELVGKYKQLISKIGHQLEAQTLVGPVHTQQNVENYKAAIAEAKSLGGTVAFG--GNV 400
            .:.:|.|::|....|:.   .|...:.....|.:.:.::.:.....|.     |..||:|  |:.
Human   372 SIQNQIVEKLKKSLKEF---YGEDAKKSRDYGRIISARHFQRVMGLIE-----GQKVAYGGTGDA 428

  Fly   401 IQRDGFYVEPTVITGLPHDASVVHRETFAPIVYILKAKNVDQAIEWNNEVEQGLSSAIFTENIGQ 465
            ..|   |:.||::|.:...:.|:..|.|.|::.|:..:::::||::.|:.|:.|:..:|:.| .:
Human   429 ATR---YIAPTILTDVDPQSPVMQEEIFGPVLPIVCVRSLEEAIQFINQREKPLALYMFSSN-DK 489

  Fly   466 AFKWIGAKGSDCGI----VNINTTTNGAEIGGAFGGEKATGGGRESGSDAWKQYCKRATITV 523
            ..|.:.|:.|..|:    |.::.|.:..    .|||...:|.|...|..:::.:..|.:..|
Human   490 VIKKMIAETSSGGVAANDVIVHITLHSL----PFGGVGNSGMGSYHGKKSFETFSHRRSCLV 547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh7A1	NP_649099.1	ALDH_F7_AASADH	51..526	CDD:143448	75/322 (23%)
ALDH3A1	XP_047291551.1	ALDH-SF	<248..564	CDD:448367	75/321 (23%)