Protein Alignment Aldh7A1 and Aldh5a1

DIOPT Version :10

• Sequence 1: NP_649099.1
• Gene: Aldh7A1 / 40097
• FlyBaseID: FBgn0036857
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_766120.1
• Gene: Aldh5a1 / 214579
• MGIID: 2441982
• Length: 523
• Species: Mus musculus
• Alignment Length: 515
• Identity: 142/515 - (27%)
• Similarity: 239/515 - (46%)
• Gaps: 46/515 - (8%)

  Fly    14 PRRLVTQTASYSSSSSYLIDQPEYSFLKELGLERD---NPGVYSGQWQGRGPSVTSYDPGTGQPI 75
            |||      ||:|...              ||..|   ......|:|.....:...|||.:|..:
Mouse    31 PRR------SYASGPG--------------GLHADLLRGDSFVGGRWLPAPATFPVYDPASGAKL 75

  Fly    76 AKVRQGNVQELEHTIGLAVEAYKQWRQVPAPVRGEIVRQIGDELRKYKEPLGKLVSLEVGKIYSE 140
            ..|....|.|....:..|.:|:..|:.|....|..::|:..|.:.:.|:.|.|:::.|.||...|
Mouse    76 GTVADCGVPEARAAVRAAYDAFNSWKGVSVKERSLLLRKWYDLMIQNKDDLAKIITAESGKPLKE 140

  Fly   141 GQGEV---QEFIDICDYAVGLSRIYSGQLINSERADHSILEAWRPLGVVGVISAYNFPNAVFGWN 202
            .|||:   ..|::.  ::....||| |.:|.:...|...|...:|:||..:|:.:|||:|:....
Mouse   141 AQGEILYSALFLEW--FSEEARRIY-GDIIYTSAKDKRGLVLKQPVGVAAIITPWNFPSAMITRK 202

  Fly   203 AAIALTTGNSVLWKGAPSTPLVSVATTKIVAEVLRRNNLPP----VVTLCQG-GTDVGQTLVADK 262
            ...||..|.:|:.|.|..||..::|    :|::..:..:|.    |:...:. ..:||:.|..|.
Mouse   203 VGAALAAGCTVVVKPAEDTPYSALA----LAQLANQAGIPAGVYNVIPCSRNKAKEVGEVLCTDP 263

  Fly   263 RVNLVSFTGSCQTGRDVGVEVQRRFGKVILELGGNNALIIDESANVKMALDAALFGCIGTSGQRC 327
            .|:.:|||||..||:.:.........:|.:||||....|:.:||||..|:..|:......:||.|
Mouse   264 LVSKISFTGSTATGKILLHHAANSVKRVSMELGGLAPFIVFDSANVDQAVAGAMASKFRNAGQTC 328

  Fly   328 TTTRRIIVHEKLHDQFVKELVGKYKQLISKIGHQLEAQTLVGPVHTQQNVENYKAAIAEAKSLGG 392
            ..:.|.:|...:||.||.:.....|:.: ::|:..|..|..||:..::.||..:..:.:|.:.|.
Mouse   329 VCSNRFLVQRGIHDSFVTKFAEAMKKSL-RVGNGFEEGTTQGPLINEKAVEKVEKQVNDAVAKGA 392

  Fly   393 TVAFGGNVIQRDGFYVEPTVITGLPHDASVVHRETFAPIVYILKAKNVDQAIEWNNEVEQGLSSA 457
            ||..||...|..|.:.|||:::.:..|...:..|||.|:..::|....::|:...|..|.||:..
Mouse   393 TVVTGGKRHQSGGNFFEPTLLSNVTRDMLCITEETFGPLAPVIKFDKEEEAVAIANAAEVGLAGY 457

  Fly   458 IFTENIGQAFKWIGAKGSDCGIVNINTTTNG--AEIGGAFGGEKATGGGRESGSDAWKQY 515
            .::::..|.  |..|:..:.|:|.:|   .|  :.:...|||.|.:|.|||.......:|
Mouse   458 FYSQDPAQI--WRVAEQLEVGMVGVN---EGLISSVECPFGGVKQSGLGREGSKYGIDEY 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh7A1	NP_649099.1	ALDH_F7_AASADH	51..526	CDD:143448	133/475 (28%)
Aldh5a1	NP_766120.1	SSADH	66..516	CDD:188167	131/460 (28%)