Protein Alignment Aldh7A1 and Aldh4a1

DIOPT Version :10

• Sequence 1: NP_649099.1
• Gene: Aldh7A1 / 40097
• FlyBaseID: FBgn0036857
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_780647.3
• Gene: Aldh4a1 / 212647
• MGIID: 2443883
• Length: 562
• Species: Mus musculus
• Alignment Length: 477
• Identity: 114/477 - (23%)
• Similarity: 198/477 - (41%)
• Gaps: 77/477 - (16%)

  Fly    75 IAKVRQGNVQELEHTIGLAVEAYKQWRQVPAPVRGEIVRQIGDELR--KYKEPLGKLVSLEVGKI 137
            :||....:...|...|..|:.|.|:|...|...|.::..:..|.|.  :..|.|.|.:   ||
Mouse    90 VAKFCYADKALLNRAIDAALAARKEWDLKPMADRAQVFLKAADMLSGPRRAEVLAKTM---VG-- 149

  Fly   138 YSEGQGEVQEFIDICDYAVGLSRIYSGQLINSE---------RADHSILEAWRPL-GVVGVISAY 192
              :|:..:|..||.....:...|..:...:..|         ..:|::   :|.| |.|..||.:
Mouse   150 --QGKTVIQAEIDAAAELIDFFRFNAKFAVELEGEQPISVPPSTNHTV---YRGLEGFVAAISPF 209

  Fly   193 NFPNAVFGWNAAIALTTGNSVLWKGAPSTPLVSVATTKIVAEVLRRNNLPP--VVTLCQGGTDVG 255
            || .|:.|..|......||.||||.:.:..|.|.|    |..:||...|||  :..:...|...|
Mouse   210 NF-TAIGGNLAGAPALMGNVVLWKPSDTAMLASYA----VYRILREAGLPPNIIQFVPADGPTFG 269

  Fly   256 QTLVADKRVNLVSFTGSCQTGRDVGVEVQ------RRFGKVILELGGNNALIIDESANVKMALDA 314
            .|:.:.:.:..::||||..|.:.:..:|.      |.|.::..|.||.|...:..||:|...:..
Mouse   270 DTVTSSEHLCGINFTGSVPTFKHLWRQVAQNLDRFRTFPRLAGECGGKNFHFVHSSADVDSVVSG 334

  Fly   315 ALFGCIGTSGQRCTTTRRIIVHEKLHDQFVKELVGKYKQLISKIGHQLEAQTLVGPVHTQQNVEN 379
            .|.......||:|:...|:.|.:.|..|....|:.::.::  |:|...|            :...
Mouse   335 TLRSAFEYGGQKCSACSRLYVPKSLWPQIKGRLLEEHSRI--KVGDPAE------------DFGT 385

  Fly   380 YKAAIAEAKSLGG--------------TVAFGGNVIQRDGFYVEPTVITGLPHDASVVHRETFAP 430
            :.:|:.:||:...              ::..||...:..|:||||.:|........::..|.|.|
Mouse   386 FFSAVIDAKAFARIKKWLEHARSSPSLSILAGGQCNESVGYYVEPCIIESKDPQEPIMKEEIFGP 450

  Fly   431 I--VYIL---KAKNVDQAIEWNNEVEQGLSSAIFTEN---IGQAFKWIGAKGSDCGIVNINTTTN 487
            :  ||:.   |.:...|.::  :....||:.|:|.::   :.:|.:.:   .:..|...||..:.
Mouse   451 VLTVYVYPDDKYRETLQLVD--STTSYGLTGAVFAQDKAIVQEATRML---RNAAGNFYINDKST 510

  Fly   488 GAEIG-GAFGGEKATGGGRESG 508
            |:.:| ..|||.:|:|...:.|
Mouse   511 GSVVGQQPFGGARASGTNDKPG 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh7A1	NP_649099.1	ALDH_F7_AASADH	51..526	CDD:143448	114/477 (24%)
Aldh4a1	NP_780647.3	ALDH_F4-17_P5CDH	31..552	CDD:143441	114/477 (24%)