Protein Alignment Aldh7A1 and alh-2

DIOPT Version :10

• Sequence 1: NP_649099.1
• Gene: Aldh7A1 / 40097
• FlyBaseID: FBgn0036857
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_503467.2
• Gene: alh-2 / 187001
• WormBaseID: WBGene00000108
• Length: 514
• Species: Caenorhabditis elegans
• Alignment Length: 477
• Identity: 132/477 - (27%)
• Similarity: 224/477 - (46%)
• Gaps: 31/477 - (6%)

  Fly    61 GPSVTSYDPGTGQPIAKVRQGNVQELEHTIGLAVEAYK---QWRQVPAPVRGEIVRQIGDELRKY 122
            |.:....:|..|:.:|||.:||..:::..:..|.:|:|   :||::.|..||.::.::.|.:.:.
 Worm    48 GKTFEFVNPANGKLLAKVAEGNRDDVDIAVEAAKKAFKIGSEWRRMDASHRGVLLNRLADLMERD 112

  Fly   123 KEPLGKLVSLEVGKIYSEGQGEVQEFIDICDYAVGLSRIYSGQLINSE------RADHSILEAWR 181
            :..|..|.||:.||.|.|...     ||: ..::...|.|:|....:.      ..|:.......
 Worm   113 RVILASLESLDNGKPYKEAYN-----IDL-PISIKTFRYYAGYADKNHGKTIPVGGDYFTYTRHE 171

  Fly   182 PLGVVGVISAYNFPNAVFGWNAAIALTTGNSVLWKGAPSTPLVSVATTKIVAEVLRRNNLPP-VV 245
            |:||.|.|..:|||..:..|..|.||..||:|:.|.|..|||.::.    ||.:::....|. ||
 Worm   172 PVGVCGQIIPWNFPLLMQAWKLAPALAMGNTVVMKVAVKTPLSALH----VASLIKEAQFPEGVV 232

  Fly   246 TLCQG-GTDVGQTLVADKRVNLVSFTGSCQTGRDV-GVEVQRRFGKVILELGGNNALIIDESANV 308
            .:..| |||.|:.:.:...|:.|:||||.:.|:.: ....:....||.|||||.:..|:...|::
 Worm   233 NIIPGRGTDAGEAIASHMDVDKVAFTGSTEVGKTIMKAAAESNVKKVTLELGGKSPNIVFADADL 297

  Fly   309 KMALDAALFGCIGTSGQRCTTTRRIIVHEKLHDQFVKELVGKYKQLISK--IGHQLEAQTLVGPV 371
            :.|:..:........||.|:...|..|..|::|:|    |.|.|:|:.|  ||...:..|..||.
 Worm   298 EEAVRQSHHALFFNQGQCCSAGSRTFVEGKIYDEF----VAKAKELVEKTVIGDPFDENTTQGPQ 358

  Fly   372 HTQQNVENYKAAIAEAKSLGGTVAFGGNVIQRDGFYVEPTVITGLPHDASVVHRETFAPIVYILK 436
            ..:..||.....|...|..|..:..||......|::|:||:...:.....:...|.|.|::.:::
 Worm   359 IDESQVETIMKYIESGKKEGAQLVTGGVKHGDQGYFVKPTIFANVNDQMKIAQEEIFGPVMIVIR 423

  Fly   437 AKNVDQAIEWNNEVEQGLSSAIFTENIGQAFKWIGAKGSDCGIVNINTTTNGAEIGGAFGGEKAT 501
            ..::::.||..|....||::.:.|.::.:|.:......:....||.....:.|   ..|||.|.:
 Worm   424 FDSMEELIEKANNTIYGLAAGVVTNDLNKALQVANTIRAGSVWVNCYDVFDPA---APFGGFKQS 485

  Fly   502 GGGRESGSDAWKQYCKRATITV 523
            |.|||.|......|.:..|:|:
 Worm   486 GIGRELGEYGLAAYTEVKTVTI 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh7A1	NP_649099.1	ALDH_F7_AASADH	51..526	CDD:143448	132/477 (28%)
alh-2	NP_503467.2	ALDH_F1-2_Ald2-like	34..507	CDD:143410	131/475 (28%)