Protein Alignment Aldh7A1 and ALDH16A1

DIOPT Version :10

• Sequence 1: NP_649099.1
• Gene: Aldh7A1 / 40097
• FlyBaseID: FBgn0036857
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_699160.2
• Gene: ALDH16A1 / 126133
• HGNCID: 28114
• Length: 802
• Species: Homo sapiens
• Alignment Length: 464
• Identity: 114/464 - (24%)
• Similarity: 206/464 - (44%)
• Gaps: 39/464 - (8%)

  Fly    54 SGQW---QGRGPSVTSYDPGTGQPIAKVRQGNVQELEHTIGLAVEAYKQWRQVPAPVRGEIVRQI 115
            :|:|   :.|. ||...||.||:.:|...|...:::...:..|..|:|.|...|..||.:.:.::
Human    45 NGKWLKPEHRN-SVPCQDPITGENLASCLQAQAEDVAAAVEAARMAFKGWSAHPGVVRAQHLTRL 108

  Fly   116 GDELRKYKEPLGKLVSLEVGKIYSE-GQGEVQEFIDICDYAVGLSRIYSGQLINSERADHSILEA 179
            .:.::|::..|..|.||..|:...| ..|:||       .|..|...::.|....|.|    |..
Human   109 AEVIQKHQRLLWTLESLVTGRAVREVRDGDVQ-------LAQQLLHYHAIQASTQEEA----LAG 162

  Fly   180 WRPLGVVGVISAYNFPNAVFGWNAAIALTTGNSVLWKGAPSTPLVSVATTKIVAEVLRRNNLPPV 244
            |.|:||:|:|....|......|....||..|.:|:....|::| ..:...::..|:   ...|.:
Human   163 WEPMGVIGLILPPTFSFLEMMWRICPALAVGCTVVALVPPASP-APLLLAQLAGEL---GPFPGI 223

  Fly   245 VTLCQGGTDVGQTLVADKRVNLVSFTGSCQTGRDVGVEVQRRFGKVILELGGNNALIIDESANVK 309
            :.:..|...:...|.:...:..|:|.|:.:.||.:...:.....::.|.||..:.|::.::|:|
Human   224 LNVLSGPASLVPILASQPGIRKVAFCGAPEEGRALRRSLAGECAELGLALGTESLLLLTDTADV- 287

  Fly   310 MALDAALFGCIGTS-GQRCTTTRRIIVHEKLHDQFVKELVGKYKQLISKIGHQLEAQTLVGPVHT 373
               |:|:.|.:..: ..|.....|:::.|.:.|:.::.|..:..:|.|  |..|:....:| ...
Human   288 ---DSAVEGVVDAAWSDRGPGGLRLLIQESVWDEAMRRLQERMGRLRS--GRGLDGAVDMG-ARG 346

  Fly   374 QQNVENYKAAIAEAKSLGGTVAFGGNVIQRDGFYVEPTVITGLPHDASVVHRETFAPIVYILKAK 438
            ....:..:..:.||:|.|..|...|:|.....|| .||:::.||..:.....|...|:|.....:
Human   347 AAACDLVQRFVREAQSQGAQVFQAGDVPSERPFY-PPTLVSNLPPASPCAQVEVPWPVVVASPFR 410

  Fly   439 NVDQAIEWNNEVEQGLSSAIFTENIGQAFKWIGAKGSDCGIVNINTTTNGAEIGGAFGGEKATGG 503
            ...:|:...|...:|.|:::::|.:|||.: :| .|...|.|.||.       .|.......|||
Human   411 TAKEALLVANGTPRGGSASVWSERLGQALE-LG-YGLQVGTVWINA-------HGLRDPSVPTGG 466

  Fly   504 GRESGSDAW 512
            .:|||. :|
Human   467 CKESGC-SW 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh7A1	NP_649099.1	ALDH_F7_AASADH	51..526	CDD:143448	114/464 (25%)
ALDH16A1	NP_699160.2	ALDH-SF	19..492	CDD:448367	114/464 (25%)
		AdhE	525..>767	CDD:440636