Protein Alignment Aldh7A1 and aldh1l2

DIOPT Version :10

• Sequence 1: NP_649099.1
• Gene: Aldh7A1 / 40097
• FlyBaseID: FBgn0036857
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: XP_002661418.2
• Gene: aldh1l2 / 100333269
• ZFINID: ZDB-GENE-100426-6
• Length: 923
• Species: Danio rerio
• Alignment Length: 484
• Identity: 136/484 - (28%)
• Similarity: 237/484 - (48%)
• Gaps: 36/484 - (7%)

  Fly    61 GPSVTSYDPGTGQPIAKVRQGNVQELEHTIGLAVEAYKQ--WRQVPAPVRGEIVRQIGDELRKYK 123
            |.:..:.:|..|..|.||...:|.:::..:..|.||:..  |.::....||:::.::.|.:.:::
Zfish   457 GKTYNTVNPTDGSVICKVSYASVADVDKAVSAAKEAFDNGPWGKMNPRDRGQLLYRLADLMEEHQ 521

  Fly   124 EPLGKLVSLEVGKIYSEG-QGEVQEFIDICDYAVGLSRIYSGQL--INSERADHSI-LEAWRPLG 184
            |.|..:.:::.|.:|:.. :..|...|....|..|......|..  ||..|.:.:: .....|||
Zfish   522 EELATIETIDSGAVYTLALKTHVGMSIQTFRYFAGWCDKIQGSTIPINQARPNRNLTFTKKEPLG 586

  Fly   185 VVGVISAYNFPNAVFGWNAAIALTTGNSVLWKGAPSTPLVSVATTKIVAEVLRRNNLPP-VVTLC 248
            |..::..:|:|..:..|.:|..|..||:::.|.|..|||.::.    .||:..:..:|. |:.:.
Zfish   587 VCAIVIPWNYPLMMLAWKSAACLAAGNTLVLKPAQVTPLTALK----FAELTIKAGIPKGVINIV 647

  Fly   249 QG-GTDVGQTLVADKRVNLVSFTGSCQTGRDVGVE-VQRRFGKVILELGGNNALII----DESAN 307
            .| |..|||.:.....:..:.||||...|:.:... ......||.|||||.:.|||    |....
Zfish   648 PGSGGLVGQRMSEHPDIRKLGFTGSTPIGKQIMKSCAVSNLKKVSLELGGKSPLIIFSDCDMDKA 712

  Fly   308 VKMALDAALFGCIGTSGQRCTTTRRIIVHEKLHDQFVKELVGKYKQLISKIGHQLEAQTLVGP-- 370
            |:|.:.:..|    ..|:.|....|:.|.|.:||::::.:|.:.|::  |||..|:..|..||
Zfish   713 VRMGMSSVYF----NKGENCIAAGRLFVEESIHDEYIRRVVEEIKKM--KIGDPLDRSTDHGPQN 771

  Fly   371 --VHTQQNVENYKAAIAEAKSLGGTVAFGGNVIQRDGFYVEPTVITGLPHDASVVHRETFAPIVY 433
              .|..:.||..:..:.|    |.|:.:||..:.|.||::||||.|.:.....:...|:|.|::.
Zfish   772 HKAHMDKLVEYCEIGVKE----GATLVYGGRQVDRPGFFMEPTVFTDVEDHMFIAKEESFGPVMV 832

  Fly   434 ILKAK--NVDQAIEWNNEVEQGLSSAIFTENIGQAFKWIGAKGSDCGIVNINTTTNGAEIGGAFG 496
            :.|.|  :||..:...|:.|.||:|.:||.:|.:|. ::..: .:.|.|.|| |.|..::...||
Zfish   833 VSKFKDGDVDGVLSRANDTEFGLASGVFTRDINKAM-YVSER-LEAGTVFIN-TYNKTDVAAPFG 894

  Fly   497 GEKATGGGRESGSDAWKQYCKRATITVNH 525
            |.|.:|.|::.|.||..:|.:...:||.:
Zfish   895 GFKQSGFGKDLGEDALHEYLRTKAVTVEY 923

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh7A1	NP_649099.1	ALDH_F7_AASADH	51..526	CDD:143448	136/484 (28%)
aldh1l2	XP_002661418.2	FMT_core_FDH_N	23..225	CDD:187716
		FDH_Hydrolase_C	228..327	CDD:187731
		PP-binding	346..407	CDD:425746
		ALDH_F1L_FTFDH	438..923	CDD:143458	136/482 (28%)