DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rept and pont

DIOPT Version :9

Sequence 1:	NP_001262040.1	Gene:	rept / 40092	FlyBaseID:	FBgn0040075	Length:	481	Species:	Drosophila melanogaster
Sequence 2:	NP_652608.1	Gene:	pont / 53439	FlyBaseID:	FBgn0040078	Length:	456	Species:	Drosophila melanogaster

Alignment Length:	453	Identity:	205/453 - (45%)
Similarity:	300/453 - (66%)	Gaps:	15/453 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 EVRDVTRIERIGAHSHIRGLGLDDVLEARLVSQGMVGQKDARRAAGVVVQMVREGKIAGRCILLA 72
            ||:...|.:||.||||::|||||:|..|...:.|:||||.||.|||:||.:::..|:|||.:|||
  Fly     5 EVKSTVRTQRIAAHSHVKGLGLDEVGAAVHSAAGLVGQKAAREAAGIVVDLIKSKKMAGRALLLA 69

  Fly    73 GEPSTGKTAIAVGMAQALGTETPFTSMSGSEIYSLEMSKTEALSQALRKSIGVRIKEETEIIEGE 137
            |.|.|||||||:.:||.||.:.||..|.|||::|.|:.|||.|.:..|:|||:||:|..|:.|||
  Fly    70 GPPGTGKTAIALAIAQELGNKVPFCPMVGSEVFSNEIKKTEVLMENFRRSIGLRIRETKEVYEGE 134

  Fly   138 VVE---IQIERPASGTGQKVGKVT--LKTTEMETNYDLGNKIIECFMKEKIQAGDVITIDKASGK 197
            |.|   ::.|.|..|.|:.:..|.  |||.:......|...|.:...|||::.||||.|:..||.
  Fly   135 VTELTPVETENPMGGYGKTISNVVIGLKTAKGTKQLKLDPSIFDALQKEKVEVGDVIYIEANSGA 199

  Fly   198 VNKLGRSFTRARDYDATGAQTRFVQCPEGELQKRKEVVHTVTLHEIDVINSRTHG-------FLA 255
            |.:.|||.|.|.::|....:  :|..|:|::.|:|||:..||||::||.|:|..|       ...
  Fly   200 VKRQGRSDTFATEFDLETEE--YVPLPKGDVHKKKEVIQDVTLHDLDVANARPQGGQDVLSMMGQ 262

  Fly   256 LFSGDTGEIKQEVRDQINNKVLEWREEGKAEINPGVLFIDEVHMLDIECFSFLNRALESDMAPVV 320
            |......||..::|.:||..|.::.::|.||:.||||||||:||||:|.|::|:::|||.:||:|
  Fly   263 LMKPKKTEITDKLRMEINKVVNKYIDQGIAELVPGVLFIDEIHMLDLETFTYLHKSLESPIAPIV 327

  Fly   321 VMATNRGITRIRG-TNYRSPHGIPIDLLDRMIIIRTVPYSEKEVKEILKIRCEEEDCIMHPDALT 384
            :.|||||...||| |:..||||||:|||||::||||:.||..::::|:|:|.:.|...:..:|.|
  Fly   328 IFATNRGRCVIRGTTDIVSPHGIPLDLLDRLLIIRTLLYSTADMEQIIKLRAQTEGLQLEENAFT 392

  Fly   385 ILTRIATDTSLRYAIQLITTANLVCRRRKATEVNTEDVKKVYSLFLDENRSSKILKEYQDDYM 447
            .|:.|.|.::||||:||:|.|:.:|:.....:::.:|::.|:|||||..||||.|.|..:.:|
  Fly   393 RLSEIGTSSTLRYAVQLLTPAHQMCKVNGRNQISKDDIEDVHSLFLDAKRSSKHLSEKNNKFM 455

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rept	NP_001262040.1	TIP49	17..408	CDD:283678	187/403 (46%)
		P-loop_NTPase	69..>113	CDD:304359	25/43 (58%)
		AAA	<267..358	CDD:99707	52/91 (57%)
pont	NP_652608.1	TIP49	14..413	CDD:283678	186/400 (47%)
		P-loop_NTPase	40..>80	CDD:304359	25/39 (64%)
		P-loop_NTPase	66..>110	CDD:304359	25/43 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464701
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1224
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D273414at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11093
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850