Protein Alignment rept and ruvb-1

DIOPT Version :10

• Sequence 1: NP_524156.1
• Gene: rept / 40092
• FlyBaseID: FBgn0040075
• Length: 481
• Species: Drosophila melanogaster
• Sequence 2: NP_505567.2
• Gene: ruvb-1 / 179388
• WormBaseID: WBGene00007784
• Length: 476
• Species: Caenorhabditis elegans
• Alignment Length: 445
• Identity: 186/445 - (41%)
• Similarity: 277/445 - (62%)
• Gaps: 23/445 - (5%)

  Fly    14 RIERIGAHSHIRGLGLD-DVLEARLVSQGMVGQKDARRAAGVVVQMVREGKIAGRCILLAGEPST 77
            :|:||.||||::|||:| :..||...:.|.|||..||.||.:||.|:|...:|||.:|:||.|:|
 Worm    29 QIKRIAAHSHVKGLGIDTETQEAHYEAAGFVGQAPARTAASIVVDMIRLKCMAGRAVLIAGPPAT 93

  Fly    78 GKTAIAVGMAQALGTETPFTSMSGSEIYSLEMSKTEALSQALRKSIGVRIKEETEIIEGEVVEIQ 142
            ||||||:.|:|.||...||..:..||::|.|:.|||.|.::.|::||:|:||..::.||||.|:.
 Worm    94 GKTAIALAMSQELGDGVPFVPLVASEVFSNEVKKTEVLMRSFRRAIGLRVKETKDVYEGEVTELS 158

  Fly   143 IERPA--SGTGQKVGK--VTLKTTEMETNYDLGNKIIECFMKEKIQAGDVITIDKASGKVNKLGR 203
            ....:  ||.|:.:..  ::|||.:......|...|.:..:|::::.||||.|:..||.|.::||
 Worm   159 PVEASDNSGMGKTISHLVLSLKTAKGSKQLKLDPSIYDSILKQRVEVGDVIYIEANSGIVKRVGR 223

  Fly   204 SFTRARDYDATGAQTRFVQCPEGELQKRKEVVHTVTLHEIDVINSRTHGFLALFSGDTG------ 262
            ....|.::|....:  ||..|:|:::|.|::|..|:||::|:.|:|..|    ..||..
 Worm   224 CDVYASEFDLEADE--FVPMPKGDVRKSKDIVQNVSLHDLDIANARPQG----RQGDVSNIVSQL 282

  Fly   263 ------EIKQEVRDQINNKVLEWREEGKAEINPGVLFIDEVHMLDIECFSFLNRALESDMAPVVV 321
                  |:...:|.:||..|.|:.|.|.||:.|||||||||||||:|||::|.|||||.||||||
 Worm   283 MTPKKTEVTDRLRSEINKVVNEYIESGVAELMPGVLFIDEVHMLDVECFTYLYRALESPMAPVVV 347

  Fly   322 MATNRGITRIRGTNYRSPHGIPIDLLDRMIIIRTVPYSEKEVKEILKIRCEEEDCIMHPDALTIL 386
            .|||||.|.:||...::|||||.::|||::||.|:.|:|:::::||..|.|.|:......|..:|
 Worm   348 FATNRGTTTVRGLGDKAPHGIPPEMLDRLMIIPTMKYNEEDIRKILVHRTEAENVQFEEKAFDLL 412

  Fly   387 TRIATDTSLRYAIQLITTANLVCRRRKATEVNTEDVKKVYSLFLDENRSSKILKE 441
            :::..:.|||||:|||..|.|..:......:..|||.:...||:|...|.|..:|
 Worm   413 SKVGAEKSLRYALQLIAPARLCAQTCGREVIEVEDVDRCTKLFMDRGESLKKAEE 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rept	NP_524156.1	TIP49	17..361	CDD:399217	158/360 (44%)
		TIP49_C	366..431	CDD:436097	22/64 (34%)
ruvb-1	NP_505567.2	TIP49	32..387	CDD:399217	158/360 (44%)
		TIP49_C	392..457	CDD:436097	22/64 (34%)