Protein Alignment rept and SPATA5

DIOPT Version :9

• Sequence 1: NP_001262040.1
• Gene: rept / 40092
• FlyBaseID: FBgn0040075
• Length: 481
• Species: Drosophila melanogaster
• Sequence 2: XP_016863314.1
• Gene: SPATA5 / 166378
• HGNCID: 18119
• Length: 917
• Species: Homo sapiens
• Alignment Length: 586
• Identity: 110/586 - (18%)
• Similarity: 192/586 - (32%)
• Gaps: 210/586 - (35%)

  Fly    28 GLDDVLEA-RLVSQGMVGQKDARRAAGVVVQMVREGKIAGRCILLAGEPSTGKTAIAVGMAQALG 91
            ||...|:| |.:.:..:.|.:..::.|:.         |.|.:||.|.|.||||.||..:|..:|
Human   357 GLSSQLKAIREIIELPLKQPELFKSYGIP---------APRGVLLYGPPGTGKTMIARAVANEVG 412

  Fly    92 TETPFTSMSGSEIYSLEMSKTEA---------------------LSQALRKSIGVRIKEE----- 130
            ...  :.::|.||.|....:|||                     |.....|..|.:.:.|
Human   413 AYV--SVINGPEIISKFYGETEAKLRQIFAEATLRHPSIIFIDELDALCPKREGAQNEVEKRVVA 475

  Fly   131 ----------TEIIEGEVV-----------------------EIQIERPASGTGQKVGKVTLK-- 160
                      :|:.||:|:                       ||:|..|.:.....:.:..|:
Human   476 SLLTLMDGIGSEVSEGQVLVLGATNRPHALDAALRRPGRFDKEIEIGVPNAQDRLDILQKLLRRV 540

  Fly   161 ---TTEME-------------------TNYDLGNKIIECFM-----------------------K 180
               .||.|                   .|...|.:|::..|                       |
Human   541 PHLLTEAELLQLANSAHGYVGADLKVLCNEAAGTRILKAHMYVSAFATGLTQTPQGLCALRRILK 605

  Fly   181 EKIQAGDVITIDKASGKVNKLGRSFTRA-RDYDATGAQTRFVQCPE------GELQ----KRKEV 234
            ::....||    |.:|.|....:.|.:| .|...:..:...:..|.      |.|:    |.::.
Human   606 KQPNLPDV----KVAGLVKITLKDFLQAMNDIRPSAMREIAIDVPNVSWSDIGGLESIKLKLEQA 666

  Fly   235 VHTVTLHEIDVI----------------------------NSRTHGFLA-----LFSGDTGEIKQ 266
            |.....|....|                            |.....|||     |.:...||.::
Human   667 VEWPLKHPESFIRMGIQPPKGVLLYGPPGCSKTMIAKALANESGLNFLAIKGPELMNKYVGESER 731

  Fly   267 EVRDQINNKVLEWREEGKAE-INPGVLFIDEVHMLDIECFSFLNRALESDMAPVVVMATNRGITR 330
            .||:...          ||. :.|.::|.||:..|.:|..|.|.....:|.....::....||.:
Human   732 AVRETFR----------KARAVAPSIIFFDELDALAVERGSSLGAGNVADRVLAQLLTEMDGIEQ 786

  Fly   331 IRGTNYRSPHGIPIDLLDRMII-------IRTVPYSEKEV-KEILKIR---------CEEEDCIM 378
            ::.....:....| |.:|:.::       |..||..:... :||.|::         .:.::.|:
Human   787 LKDVTILAATNRP-DRIDKALMRPGRIDRIIYVPLPDAATRREIFKLQFHSMPVSNEVDLDELIL 850

  Fly   379 HPDA-----LTILTRIATDTSLRYAIQLITTANLVCRRRKATEVNT------EDVKKVYSLFLDE 432
            ..||     :..:.|.|...:|...||    |||:.:|.....::|      |.:::.|..:.::
Human   851 QTDAYSGAEIVAVCREAALLALEEDIQ----ANLIMKRHFTQALSTVTPRIPESLRRFYEDYQEK 911

  Fly   433 N 433
            :
Human   912 S 912

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rept	NP_001262040.1	TIP49	17..408	CDD:283678	105/553 (19%)
		P-loop_NTPase	69..>113	CDD:304359	16/43 (37%)
		AAA	<267..358	CDD:99707	20/98 (20%)
SPATA5	XP_016863314.1	CDC48_N	65..133	CDD:389870
		CDC48	<323..913	CDD:273521	110/586 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910