DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Gem2 and gemin2

DIOPT Version :9

Sequence 1:	NP_001262034.1	Gene:	Gem2 / 40087	FlyBaseID:	FBgn0036850	Length:	245	Species:	Drosophila melanogaster
Sequence 2:	NP_001017608.1	Gene:	gemin2 / 550271	ZFINID:	ZDB-GENE-030131-3756	Length:	253	Species:	Danio rerio

Alignment Length:	267	Identity:	72/267 - (26%)
Similarity:	112/267 - (41%)	Gaps:	52/267 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 QLQALEICEPDSSFDPQKPPESGEEYLMHMFYERKRCPAVVTKR--SSKIRNNTGNTTLE-MLDN 72
            :|..::.|:.: .:...:||.:.:|||..:..|...||.||..:  ..|::..:.|.::. .|..
Zfish     3 RLLPVDSCDTE-EYTLTEPPRNPQEYLRFVQREASLCPDVVVAQIDPKKLKKQSVNVSITGCLAA 66

  Fly    73 PE--LPPFKCLLPTPEWRDEQVKSFQAARSQVLVLRKELANNNYDQSGEPPLTSDQEKWKEFCRN 135
            ||  .|.||       |:.:||..|...|..|...|:.......|.:...|.|.|::.||.||..
Zfish    67 PEGFSPSFK-------WQQQQVSRFSEVRQSVNKHRQHWKAQFLDDNVVMPKTEDEDGWKRFCLG 124

  Fly   136 QQ-------------------------PLLSTLLHLTQNDLELLLEMLSKWLQD----PNTTVDL 171
            :.                         |.||.:..|:|:.:..:||.|..|.::    |.
Zfish   125 ENVCLEIQLKEEDGVNPGLDYVKTGFPPFLSIVSKLSQSTVSAVLEYLINWFEERAFVPQ----- 184

  Fly   172 LHDVWLARWLYATLVCLHLPLEPHVFSTLRYIARTCIHLRNQLKEDEVQRAAPYNLLLTLTVQVF 236
                 |.|||||.|.||..||.|...|.:|.:||.|..:|..|:..:..|.:..||::.:..:.|
Zfish   185 -----LGRWLYALLACLEKPLLPEAHSLIRQLARRCSAVRANLESKDDDRLSALNLMICIVARYF 244

  Fly   237 AQNDFKD 243
            .|||..|
Zfish   245 EQNDLAD 251

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gem2	NP_001262034.1	SIP1	18..239	CDD:282754	67/254 (26%)
gemin2	NP_001017608.1	SIP1	10..247	CDD:282754	67/254 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170596842
Domainoid	1	1.000	91	1.000	Domainoid score	I7730
eggNOG	1	0.900	-	-		E1_28H7D
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37827
Inparanoid	1	1.050	98	1.000	Inparanoid score	I5023
OMA	1	1.010	-	-		QHG55374
OrthoDB	1	1.010	-	-		D1235594at2759
OrthoFinder	1	1.000	-	-		FOG0005780
OrthoInspector	1	1.000	-	-		oto39349
orthoMCL	1	0.900	-	-		OOG6_104791
Panther	1	1.100	-	-	LDO	PTHR12794
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6261
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.770