Protein Alignment Gem2 and smi-1

DIOPT Version :9

• Sequence 1: NP_001262034.1
• Gene: Gem2 / 40087
• FlyBaseID: FBgn0036850
• Length: 245
• Species: Drosophila melanogaster
• Sequence 2: NP_001022847.1
• Gene: smi-1 / 189726
• WormBaseID: WBGene00004886
• Length: 254
• Species: Caenorhabditis elegans
• Alignment Length: 270
• Identity: 62/270 - (22%)
• Similarity: 104/270 - (38%)
• Gaps: 62/270 - (22%)

  Fly    16 EIC-EPDSSF-----DPQKPPESGEEYLMHMFYERKRCPAVV-------------TKRSSKIRNN 61
            |.| .|...|     |...|..|..:||..|..||:....||             .|:..:...:
 Worm     4 EACLGPSDDFEADDVDMTSPAMSAAQYLRQMQAERRGTKNVVRIAQKSPDSTSPEAKKQKQWLES 68

  Fly    62 TGNTTLEMLDNPELPPFKCLLPTPEWRDEQVKSFQAARSQVLVLRKELANNNYDQSGEPPLTSDQ 126
            .|...::.::.|.  |   |:|:.|||.|:.:.|:..|:::.:..::.:....|:...|    ::
 Worm    69 VGYQEVKKIETPS--P---LIPSEEWRQEKCRKFEETRAKMALKIEKFSPMRIDRLNSP----EE 124

  Fly   127 EKWKEFCRNQ------------------QPLLSTLLHLTQNDLELLLEMLSKW-----LQDPNTT 168
            |:|.|....:                  .|.|..:..:.:..|..|:|.|..|     |..|
 Worm   125 EEWHEILLEKCLPEFQDIAGNFLNHTGTPPALRMVFSIPKRHLSQLIEYLVDWSIEEGLNRP--- 186

  Fly   169 VDLLHDVWLARWLYATLVCLHLPLEPHVFSTLRYIARTCIHLRNQLKEDEVQRAAPYNLLLTLTV 233
                    :..|:|:.|..:.|||...|.|.||.:.:.|..||::|..|....|..::|.:|:..
 Worm   187 --------IREWIYSLLAVIDLPLVQDVVSALRRLVKECRSLRSELSIDRKSEANEFSLFITIIT 243

  Fly   234 QVFAQNDFKD 243
            ..|.|.|..|
 Worm   244 IFFGQKDLAD 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gem2	NP_001262034.1	SIP1	18..239	CDD:282754	58/262 (22%)
smi-1	NP_001022847.1	SIP1	14..249	CDD:282754	55/254 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167901
Domainoid	1	1.000	65	1.000	Domainoid score	I6662
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I3925
Isobase	1	0.950	-	0	Normalized mean entropy	S3221
OMA	1	1.010	-	-		QHG55374
OrthoDB	1	1.010	-	-		D1235594at2759
OrthoFinder	1	1.000	-	-		FOG0005780
OrthoInspector	1	1.000	-	-		oto20165
orthoMCL	1	0.900	-	-		OOG6_104791
Panther	1	1.100	-	-	LDO	PTHR12794
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4058
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	13	12.890