Protein Alignment SmydA-2 and Smyd4-1

DIOPT Version :10

• Sequence 1: NP_649084.1
• Gene: SmydA-2 / 40075
• FlyBaseID: FBgn0036839
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_610500.2
• Gene: Smyd4-1 / 35985
• FlyBaseID: FBgn0033427
• Length: 751
• Species: Drosophila melanogaster
• Alignment Length: 537
• Identity: 111/537 - (20%)
• Similarity: 195/537 - (36%)
• Gaps: 121/537 - (22%)

  Fly    10 ALCQAKASQLCAACRNVVYCSREHQKEHWKKGHRSECQCFEIATN-----------------EVL 57
            |.|..|..::.:...::.|..:...||.:::......|..|:..|                 |:|
  Fly   155 AFCAWKLKKIASLEEHLDYLGQLQLKESFEQQLEDLKQKLELLKNQPREQETQGKVVDKSLGEIL 219

  Fly    58 ------GRHLRATRDIKIGEQILKEAPLVLGPKVASAPLCLGCHRNLLAPGKPRGNYHKCSSCSW 116
                  ||::.|...|..|..|..|......| :....:|..|...|::...|      |.:|..
  Fly   220 TDPGPRGRYMVAKEAISKGNVIFSERASCFVP-LEQLLICQQCAATLMSAPIP------CPNCHQ 277

  Fly   117 PL--CGKECED--SVHHKAEC--------QLMSGSNFQSK--INYVPG-EEERKESAYCVIMLLR 166
            .:  |.::|.:  |..||.||        :|:..|:...:  :.|:|. ....:|......|...
  Fly   278 RVVYCSRKCREAHSAIHKFECAAYRKDILRLLGISHLALRLLLTYIPYIRPHLQEMTSAKGMWEE 342

  Fly   167 CMHLKDKDPDA-----FLKLYNLEDHLKERLETPL-YQVLRANLI------------TFIKTVLG 213
            .|:|..|..::     :|:...:...|.:.::..| |.:|.|||:            .|......
  Fly   343 IMNLSRKPEESENAPEYLRSLRMVSQLDQAIDEELNYHILCANLLQLYLKEHTDFYDQFHSLPAS 407

  Fly   214 MKDWP---EMDILRIAAILDTN---------------TFEVRQPRERRKIRAL------------ 248
            ::||.   ...|||.|..|..|               .|.:.||...:|.|.|
  Fly   408 IEDWQLIISALILRFAGQLLANGHVGDALLGVGMEPKEFVMLQPELWQKPRHLKRGQLHNLSHSD 472

  Fly   249 ------YPGAAMISHDCVPNMRHRFDDDMNIVFLAKRKIAKGEILSISYTQPLRST--IQRRVHL 305
                  .|..::.:|.|.|::|.:| |..::|..|.:.|.:||.:...||...|::  :||...|
  Fly   473 PITAINLPYLSLCNHACEPSIRTKF-DGCSVVNYAAKDILEGEEIFNCYTMDYRNSLKLQRSHPL 536

  Fly   306 RQAKCFDCSCARC--QDPEELGSFAGAQTCLK--CKAGKIISLNPLLNSAPWKCQLCNFKRSAKD 366
            :....|:|:||:|  .||::.........|.|  |:...:.......|:..|..: ||.::....
  Fly   537 KAIYKFECTCAKCTRTDPDQNYLSFHRYRCEKPNCRQEFLPDAKVQQNNLRWWLR-CNAEKPITC 600

  Fly   367 VVTSDAELQ------QELESLDKTTPVALEEFIYRHRADL------HETNTHILQAKYALTQLYG 419
            .|..  |||      :.|..:..:...:..:.:::...||      |.:...|:..:......|.
  Fly   601 TVCH--ELQHFAWYNEFLGLIGSSADSSKRQALFKAFDDLDKWLVDHHSLKRIMAEELVTACFYE 663

  Fly   420 SAPGFAMEELSGESLNR 436
            ...|.:::|...|.|.|
  Fly   664 IDGGTSLDEFEYEDLAR 680

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SmydA-2	NP_649084.1	zf-MYND	9..46	CDD:460312	6/35 (17%)
		SET_SMYD	<227..318	CDD:380997	30/125 (24%)
Smyd4-1	NP_610500.2	SET	217..>252	CDD:394802	10/35 (29%)
		zf-MYND	258..298	CDD:460312	11/45 (24%)
		SET	<359..549	CDD:394802	45/190 (24%)