DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3902 and acds-10

DIOPT Version :9

Sequence 1:	NP_649069.2	Gene:	CG3902 / 40059	FlyBaseID:	FBgn0036824	Length:	414	Species:	Drosophila melanogaster
Sequence 2:	NP_504508.1	Gene:	acds-10 / 178962	WormBaseID:	WBGene00019599	Length:	985	Species:	Caenorhabditis elegans

Alignment Length:	441	Identity:	117/441 - (26%)
Similarity:	190/441 - (43%)	Gaps:	58/441 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 VRMLANAARQQ------SAAMSSATGLPPPLTFLTDDEKMMK--ETVAKLAQEQIQPLVKKM--- 63
            ||.||....|.      |.:....|.:|..::.     |..|  |.|.::.|..:.||.:::
Worm   552 VRKLAAEGMQMISKVHASKSYGQLTIIPSGMSL-----KAQKYYEIVREIIQNDVIPLEQELLEY 611

  Fly    64 --DFEHKF---DPSVVKAVFENGLMGI-------EIDTELG-GSG---------CNFMTNIVVVE 106
              :..|::   .|.:.|...::..:|.       .||.|.. |.|         |..|...:...
Worm   612 YEEGPHRWTIPHPKIEKLKEKSKSLGAWNLFISEHIDPEQKYGKGLTNVEYAHICELMGRSIFAP 676

  Fly   107 ELSKIDPAVAAFVDIHNTLVNSLMIKFGNAEQKAKYL-PKLAQEYAGSFALTEPG-AGSDAFSLK 169
            |:..........:::        :||:|:.|||:|:| |.|..|....||:|||. |.|||.:::
Worm   677 EVFNCQAPDTGNMEV--------LIKYGSEEQKSKWLTPLLNGEIKSCFAMTEPDVASSDATNIQ 733

  Fly   170 TVAKKDGSHYVINGSKMWISNSD-----VAGVFLIFANAKPEDGYRGITTFIVDRETPGLIVNKP 229
            ....:.|:.|:||..|.:|||:.     :| :|:...:..........:..:|..:|.|:.:.:.
Worm   734 GSIVRVGNEYIINARKWFISNASHPKCRIA-IFMGQVSGAKRSRNLQQSMILVPMQTEGVKIIRN 797

  Fly   230 EDKLGIR--ASGTCQLTFDNVRVPEENILGTFGHGYKYAAGFLNEGRIGIAAQMVGLAQGTFDAT 292
            ....|.:  ..|..::||.|||||..|:|...|.|::.|.|.|..|||..|.:::|.|:...|..
Worm   798 THVFGSQDAPGGHPEITFTNVRVPVGNMLLGEGKGFEIAQGRLGPGRIHHAMRLIGHAERAIDVI 862

  Fly   293 IPYLLERKQFGDAIYNFQSMQHQIATVATEIEAARLMTYNAARLQEQGVP--FQKEAAMAKYYAS 355
            ...||.|..||..:..|.|::.::|....|:|.|||:...||.:.:...|  .:.|.||.|..|.
Worm   863 KDRLLTRIAFGRKLVQFDSLRKELALSRCEVEQARLLVLKAAHMIDTVGPKEAKSEIAMIKVVAP 927

  Fly   356 EVAQRAAIKCVDWMGGVGFTRDFPQEKYYRDVKIGAIYEGTTNMQLSTIAK 406
            .:|.....:.:...|..|.|...|...:|...:...|.:|...:.|.||||
Worm   928 NMAISILDRAMQQQGARGLTPFTPLASFYVWARSLRIADGPDAVHLETIAK 978

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3902	NP_649069.2	CaiA	37..414	CDD:224871	109/408 (27%)
CG3902	NP_649069.2	SCAD_SBCAD	39..410	CDD:173847	109/406 (27%)
acds-10	NP_504508.1	HAD-1A3-hyp	2..212	CDD:274054
		HAD_like	<96..200	CDD:304363
		PLN02876	250..982	CDD:215473	117/441 (27%)
		ACAD10_11_N-like	250..503	CDD:270703
		ACAD_FadE2	585..982	CDD:173844	109/403 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910