Protein Alignment CG6865 and HGFAC

DIOPT Version :10

• Sequence 1: NP_001246825.1
• Gene: CG6865 / 40050
• FlyBaseID: FBgn0036817
• Length: 285
• Species: Drosophila melanogaster
• Sequence 2: NP_001284368.1
• Gene: HGFAC / 3083
• HGNCID: 4894
• Length: 662
• Species: Homo sapiens
• Alignment Length: 274
• Identity: 80/274 - (29%)
• Similarity: 128/274 - (46%)
• Gaps: 46/274 - (16%)

  Fly    26 QPCSVRN-------PKIVGGSEAERNEMPYMVSLMRRGGHFCGGTIISERWILTAGHCICNGLQQ 83
            |.|..|:       |:|:|||.:.....|::.::. .|..||.|:::...|:::|.||..:
Human   399 QACGRRHKKRTFLRPRIIGGSSSLPGSHPWLAAIY-IGDSFCAGSLVHTCWVVSAAHCFSH---- 458

  Fly    84 FMKPAQ--IQGVVGLHSIREYLNGIGNGPDALRVDFKNIVPHPQYDC-NDVKHDIALLELVQP-- 143
              .|.:  :..|:|.|    :.|...:......::  ..:|:..|.. |...||:.|:.|.:.
Human   459 --SPPRDSVSVVLGQH----FFNRTTDVTQTFGIE--KYIPYTLYSVFNPSDHDLVLIRLKKKGD 515

  Fly   144 --IRFSSHIQPSCV---GS--EEGHRSLEQEYGTVSGWGWTHENQAENDRSDVLRKATVKIWNNE 201
              ...|..:||.|:   ||  ..||:.      .::|||...||  .:..|..||:|.|.:..:.
Human   516 RCATRSQFVQPICLPEPGSTFPAGHKC------QIAGWGHLDEN--VSGYSSSLREALVPLVADH 572

  Fly   202 ACERSYRSLGKSNTIGETQLCAGYENGQIDSCWADSGGPLMSKEH---HLVGVVSTGIGCARPGL 263
            .|. |....|..  |....|||||.:.:.|:|..||||||..:::   :|.|::|.|.||.|...
Human   573 KCS-SPEVYGAD--ISPNMLCAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDGCGRLHK 634

  Fly   264 PGIYTRVSKYVSWM 277
            ||:||||:.||.|:
Human   635 PGVYTRVANYVDWI 648

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6865	NP_001246825.1	Tryp_SPc	34..276	CDD:214473	75/256 (29%)
HGFAC	NP_001284368.1	PRK14954	<32..>100	CDD:184918
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	64..102
		FN2	102..148	CDD:128373
		EGF_CA	162..197	CDD:238011
		FN1	200..240	CDD:238018
		EGF_CA	245..278	CDD:238011
		Kringle	286..367	CDD:395005
		Tryp_SPc	415..650	CDD:238113	76/258 (29%)